“a marked trend”

Furthermore, a marked trend of increased Smad7 expression was found in HFD-P compared to CT-P mice ( Figure 7 E).

Lymphoma incidence showed a marked trend towards lower rates with increasing deprivation, entirely due to Hodgkin lymphoma (HL).

( 9 ) found a marked trend toward antimicrobial drug resistance among Mexican isolates.

As text quality improves, AI content shows a marked trend toward reduced colloquialism and increased clarity, logical coherence, and linguistic formality.

Notably, higher nuclear YAP1/TAZ expression correlated with patient age and showed a marked trend toward association with extrapleural tumour location.

Disability is more closely correlated with a reduction of CMAP amplitudes indicative of axonal loss. 43 The lower limb motor and sensory potentials show a marked trend to become unexcitable over time, 45 so that the studies may not meet EFNS/PNS demyelinating criteria, with the percentage of patients meeting the criteria reported as ranging from 20.9 to 91%. 29 30 42 45 In the study reporting 20.9% however, at least 1 nerve in all patients showed demyel

A marked trend towards an earlier age at menarche has been observed over the last 150 years [9].

46 , 47 Moreover, as rural livelihoods became increasingly unsustainable owing to environmental degradation, there was a marked trend of out-migration from environmentally stressed rural areas toward urban centers or even across national borders. 25 In addition, under the SSP5-8.5 scenario, the ecological water demand for the Aral Sea was greater than that under SSP2-4.5, 12 further limiting the water resources available for agricultural irrigation.

After each treatment, a marked trend in QTc interval prolongation was observed, lasting for four chemotherapy cycles.

It is worth noting that our study is part of a marked trend toward a greater need for PC in developing countries.

The findings of this study reveal a marked trend of research in oral and maxillofacial radiology among postgraduate students at a Peruvian dental school.

Our study revealed a marked trend towards reduced apoptosis rates in roxadustat-treated mouse hearts, although the results did not attain statistical significance.

At high shear rate, there was a marked trend toward reduced thrombogenicity that did not reach statistical significance [19.6% reduction in median thrombus from 8788 (1325) μm 2 /mm to 7066 (2516) μm 2 /mm, P = 0.176] ( Fig. 3A ).

In addition, the authors found that patients with a history of cerebrovascular disease and hypertension also had a marked trend associated with CAPA [ 65 ].

The results confirmed that there was a marked trend of increasing cell viability and almost no dead cells were detected in all groups.

Compared with the 2010 measurement by Warner et al.,(2013)—when the water table stood at about 12.00 m 37 with a mean electrical conductivity of 2 376 μS/cm and mean TDS of 1 751 mg/L—the 2022 survey reveals a marked trend toward both drawdown and salinization: the average depth has increased to 19.39 m, mean EC has risen to 4 590 μS/cm (an increase of 93%), and mean TDS has climbed to 4.31 g/L (an increase of 146%).

Between 2014 and 2017, rice of European origin showed a marked trend for certain pesticides that exceeded MRLs, such as in the case of isoprothiolane or carbendazim.

Of all the predictors in the selected models for both δ 13 C and δ 15 N, only population density and July average temperature showed a marked trend over the study period and are therefore driving some of the temporal trends in δ 13 C and δ 15 N. 4 DISCUSSION In this study, we sampled the serum of Svalbard reindeer between 1995 and 2012 to identify how the winter diets of a High Arctic herbivore have changed in response to long‐term climate trends and interannual variation, mostly depicted by the “normalization” of ROS events, increased summer temperatures and increased population density.

On the other hand, there was a marked trend among patients with low circulating CXCL14 levels to have worse outcomes (composite outcome and ACM) when compared with those with higher circulating CXCL14 levels ( Figure 5 and Table 3 ).

As a final note on insulin secretion, we observed a marked trend toward lower secretion in the DJ 3-OMG group.

Even though our previous study, where we administered 5 mg/kg BW resveratrol in combination with equal amounts of quercetin and catechin, demonstrated reduced tumor growth and metastasis [ 26 , 34 ], in this study we found resveratrol alone induced a marked trend of increase in tumor growth, especially by the lower concentrations; thus, indicating a deleterious effect of resveratrol on breast cancer progression.

Arginine had a marked trend towards a significant sex interaction with OS ( p interaction = 0.07), and a significant sex interaction for RFS ( p interaction = 0.04) ( Table S13 ).

Nevertheless, there is a marked trend towards an increasing incidence of early onset CRC (less than 50 years) which has, unfortunately, obscured the positive outcome shown by the group of more than 50 years of age, which has shown a decrease in its incidence rates ( 1 ).