Barely Significant
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Molecular and clinical registry of Chilean patients diagnosed with BRAF-mutated colorectal cancer.

J Gastrointest Oncol · 2025 · PMC12598326 · PMID 41220759

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Disease stage: reference level Although patients with AJCC stage IV disease demonstrated a trend toward poorer survival than those with AJCC stage II/III disease, this difference did not reach statistical significance.

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a marked trendno p-value reported
Nevertheless, there is a marked trend towards an increasing incidence of early onset CRC (less than 50 years) which has, unfortunately, obscured the positive outcome shown by the group of more than 50 years of age, which has shown a decrease in its incidence rates ( 1 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.