Disease stage: reference level Although patients with AJCC stage IV disease demonstrated a trend toward poorer survival than those with AJCC stage II/III disease, this difference did not reach statistical significance.
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Molecular and clinical registry of Chilean patients diagnosed with BRAF-mutated colorectal cancer.
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Nevertheless, there is a marked trend towards an increasing incidence of early onset CRC (less than 50 years) which has, unfortunately, obscured the positive outcome shown by the group of more than 50 years of age, which has shown a decrease in its incidence rates ( 1 ).