15%, P =0.037) ( Figure 5A ), and there was a clear trend towards inferior survival in the multivariate model (HR=1.6, 95% CI: 1.0-2.7, P =0.058), suggesting an adverse prognostic impact of early PR on RFS which was most likely compensated by subsequent salvage therapy with regard to OS.
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After the intervention, there was a significantly greater improvement in mood, measured with the Hamilton Depression Rating Scale (HAMD), in the CBT groups compared with the CMO group ( P = 0.004), which still showed a clear trend at 3‐month follow‐up ( P = 0.058).
The absolute collagen area in the plaque was reduced (−38.3%), and a clear trend toward a lower relative collagen content of the plaque (−23%; P =0.058) was demonstrated in the ONX-0914–treated group (Figure 1 C), indicating a less progressed plaque phenotype upon ONX-0914 treatment.
Post hoc test showed that anodal stimulation of the lesioned M1 caused a clear trend ( p = 0.058) of increasing the reaching ability at a medium level of SABD loading (25%), but not for higher loads (50%).
For YAP, a clear trend toward an association with HIF-1α expression was observed ( p = 0.058, rho = 0.431). 3.
resin) demonstrated a clear trend towards better hypertrophy (f = 3.833, p = 0.058).
After correcting for age, sex, pack-years, and smoking status by ANCOVA analysis, small airway DUOX1 scoring revealed a clear trend towards significance ( P = 0.058) between GOLD IV patients (mean ± SEM: 1.582 ± 0.210) and controls (mean ± SEM: 2.487 ± 0.262).
However, selection of patients with tumour-positive lymph nodes revealed a clear trend: the worst recurrence-free survival rates occurred for ASC patients, followed by AC patients and a more favourable recurrence-free survival for SCC patients ( P = 0.058; data not shown).
The difference between fallers and non-fallers in gait flexibility when walking on an even surface displayed a clear trend ( p = 0.058).
However, a clear trend was evident also in 1st degree relatives ( p = 0.058; Supplementary Table e-4 ). 4.
Importantly, previous study also explored the transcriptome of glioma cells exposed to active CM and their RNA sequencing results show a clear trend of reduced CA11 expression under CM treatment (fold change = −0.75, P = 0.058, GSE62563 ) (Venkatesh et al ., 2015 ).
With a median follow-up of 53 months, KM OS analysis showed a difference in median OS for patients with an SS compared to patients without an SS with a clear trend for worse OS for patients with an SS approaching significance (62 versus 88 months, P=0.059) ( Figure 2A ).
CD4/Treg ratio correlated with early tumor response with a clear trend (OR 0.25, 95% CI 0.06–1.05; P = 0.059).
Furthermore, there was a clear trend for association of upregulated baseline BLVRA expression in PBL of patients with favorable CC genotype as compared to both non CC (p = 0.059) and TT IL28B (p = 0.058) patients.
No effects were observed for groups, but there was a clear trend showing higher GR-positive cells in the PSS-exposed groups (F(3, 52) = 2.6, p = 0.059).
The Dermatologic Cooperative Oncology Group (DeCOG) trial demonstrated durable improvement in both RFS and OS [ 29 ], while the French Cooperative Group trial demonstrated significant extension of RFS and a clear trend towards increased overall survival ( p = 0.059) [ 30 ].
When including the MELD score into this model, there remained a clear trend between frailty and higher mortality (odds ratio [OR] 4.351, 95% CI 0.946–20.007, P = 0.059) (Table 4 ).
Despite a clear trend in the univariate analysis, high TLG (≥159.2 g) was not significantly correlated with poor OS (P=0.059).
However, we failed to demonstrate a statistically significant correlation between CD68+ and CD3+ expression levels, although there was a clear trend (positive, p =0.059).
Such reduced model, with a loss of only 78 cases (13% of the sample size) due to missing data, resulted in a clear trend toward association between anti-HEV and hepatic cirrhosis (aOR = 1.75; 95% CI = 0.99–3.17; p = 0.059).
Although a clear trend emerged, with women showing lower well-being scores than men, this difference is not statistically significant [ t (372) = 1.89, p = 0.059].
Although post hoc comparisons did not reach statistical significance after Bonferroni correction, a clear trend toward higher TAN counts was observed in the c-erbB2-positive group compared with the c-erbB2-negative group (mean rank = 36.65 vs. 28.91, p = 0.059) ( Table 4 , Chart 4 ).
10 min, p = 0.5962); however, a complete block of activity produced a clear trend toward an increase in LP I h G max (paired t -test, p = 0.0596), and the magnitude of the increase was similar to that observed in 5 μM DA (compare Figures 2B vs. 2E ).
In P8-9 animals, HFS overall induced a clear trend towards LTD (mean amplitude during last 10 minutes post-HFS recording vs baseline, p = 0.06).
Moreover, a clear trend toward worse sexual satisfaction was observed in this group of patients (domain V; FSFI; p = 0.06).