Excerpts

With RNA-seq data, the size of the network is highly significant (p < 0.0001), with 3 transcription factors (GATA3, STAT1, and ESR1) having correlated targets enriched in the results ( Figure 4 B).

The increases in sub G1 in the 5-FU plus ATRA treated cells, when compared to cells treated with 5-FU alone, were highly significant (P<0.0001).

Indeed, we observed complete or near complete LD for all pairs of SNPs with sufficiently high frequencies (only alleles with frequencies in the range 0.05–0.95 were included in the analysis because estimates of LD for low-frequency alleles in small samples are not informative): 85% of all pairwise r 2 values were highly significant (Exact p -value <0.0001).

Specifically, the Na, Tb, Alb, age, and Cr showed highly significant associations with survival (p < 0.0001 for Na, p = 0.0055 for Tb, p = 0.00016 for Alb, p < 0.0001 for age, and p = 0.036 for Cr).

We found that performance on the digital cognitive battery and EC tau proved to be more predictive of diagnostic status than Aβ and performance on the digital cognitive battery was qualitatively better compared to tau, and this approached significance (digital cognitive battery vs cortical Aβ p < 0.0001, EC tau vs cortical Aβ p < 0.01, digital cognitive battery vs EC tau p = 0.07).

Statistical analysis confirmed highly significant effects of HC-030031 antagonism (all p < 0.0001), validating the mechanistic importance of TRPA1 in bacterial sensing.

The difference in percentage of weight gain or loss during the first week after challenge between the groups was highly significant ( P < 0.0001).

Rat control on the farm A highly significant difference (χ 2 = 33.4543 p < 0.0001) was observed in the number of T. gondii positive animals among the properties that use cats for rat control (n = 239; 20 positive animals; prevalence 1.73%) and those that do not use them (n = 885; 12 positive 1 animals; prevalence 1.03%).

Particularly in the IL1β‐negative cells, the reduction of the SF1‐HP cells was highly significant ( p < 0.0001; Figure 5m ).

Notably, plant height showed a highly significant negative correlation with leaf width ( p ≤ 0.0001), suggesting a resource allocation trade-off between vertical growth and horizontal leaf expansion.

Similarly, higher (∼1.8x) pTau181 and lower (∼0.7x) Tau levels were significantly (p<0.05) observed in ALS versus control samples and higher (mean=20.2) pTau181:Tau ratios achieved a markedly significant (p<0.0001) differentiation of ALS from controls.

This corresponded to a highly significant difference in both cold episodes and episode days of 61.1 and 72.9 % respectively ( p < 0.0001).

In this prospective cohort study of 11 G-CSF mobilized allogeneic sibling donors, there was a highly significant rise in PB [CD34 + ] and [CD34 + CD38 – ] throughout day 4 ( P <0.0001), but no reductions in the morning of day 5, as might be expected with a circadian rhythm pattern.

2B ) both showed highly significant differences in their growth curves after iron supplementation (p < 0.0001).

For both Para and non-disabled datasets, highly significant correlations were found for all peak and average HHD values (all above r = 0.95, p < 0.0001), and many of the strength measures were significantly correlated (r > 0.7, p < 0.01), except for hip external rotation.

subquinaria revealed a highly significant effect of population type (sympatric versus allopatric; Wald χ 2 = 17.88, p < 0.0001), but no effect of individual population within population type (χ 2 = 1.02, p = 0.91) or trial (χ 2 = 2.12, p = 0.35).

Statistical comparison between days 40 and 120 was highly significant (p < 0.0001).

An anova analysis of those differences (Figure S1c ) found them not significant for the factor observer (person performing the WR phenotyping, P = 0.65) and the interaction between the observer and genotype factors ( P = 0.98) but extremely significant for the factor genotype ( P < 0.0001), as expected based on the CD1–CD8 experimental series.

Overdose recovery time is highly significant ( P < 0.0001) between the Naloximeter and self-recovery ( N = 3 and 4; recovery times = 4.5 ± 0.3 and 23 ± 4 min, respectively).

M1 and M2 and M3 vs MCF7 WT and MCtrl, showed an almost four-fold increase with a highly significant difference between KO and Ctrls respectively (p ≤ 0.0001).

There was no significant effect of bird weight (LR = 0.01, df = 1, p = 0.97) or being equipped with a GPS logger (LR = 0.13, df = 1, p = 0.67) on the proportion of time at sea, but stage of the breeding season had a highly significant effect (LR = 35.97, df = 1, p < 0.0001).

Submitting the magnitude of the PSA gain to a repeated measure ANOVA with the factors direction (horizontal/vertical), eye (right/left), and estimation approach (I/II/III) showed a highly significant main effect of the factor direction ( F (1,13) = 36.1; p < 1e-4) and no other significant ( p > 0.25) main or interaction effect.

In sunn hemp, BACIII treatment induced a highly significant increase ( p < 0.0001) in all pigments compared with both controls ( Figure 8 ).

However, there was a highly significant difference in ages, with 70.7% of cases aged 0–6 months old, 29.3% aged 7–12 months and none aged more than 12 months ( P < 0.0001).

The analysis of extracts spiked with known concentrations of the compound ( Figure 3 c) showed a highly significant correlation between P5C concentration in samples and its estimation ( p < 0.0001 in a Pearson two-tailed test) and allowed us to evaluate the recovery (about 85%) and to estimate the detection limit of the method (about 20–30 nmol g −1 FW under the experimental condition used).