Excerpts

We observed a highly significant linear correlation between the cycle threshold (Ct) of both genes (beta-actin vs GAPDH, r = 0.912, F (1,46) = 157.73, p < 0.0001).

Indeed, a highly significant decrease ( p < 0.0001) in BV/TV was noted at the distal femur following maternal exposure to Cd during pregnancy and lactation compared to the control group and Zn group ( p < 0.01).

arnfieldi infection, with statistical analysis showing a highly significant variation ( p < 0.0001).

Overall, there was a highly significant correlation between these lymphoid structures and HEV density in the extra-tumoral areas ( Fig. 2e : p < 0.0001, R 2 = 0.442).

Furthermore, Tukey’s post hoc test confirmed a highly significant difference ( p < 0.0001) between these groups.

4 , with the highly significant difference in the number of cells expressing MAGE C1 in the CD19 + vs CD27 + cell populations ( p -value<0.0001) ( Fig. 4 ).

Once again, by restricting our analysis to the C/C1 overlap, we find a highly significant difference in overlap between saline and epibatidine treated [32.60 ± 5.32% (SEM); p < 0.0001].

An increasing linear trend of NS1 seroprevalence till 21-30 yr age group (Z=18.999, P <0.0001) was followed by a decreasing trend in the older population (Z=−10.691, P <0.0001) ( Supplementary Figure A and B ).

1 X 2 2 − 4.27 X 3 2 − 4.82 X 4 2 − 6.24 X 1 X 2 + 0.8271 X 1 X 3 − 1.51 X 1 X 4 − 2.48 X 2 X 3 − 1.58 X 2 X 4 + 0.0910 X 3 X 4 + 2.15 X 1 + 6.65 X 2 − 2.00 X 3 + 0.7997 X 4 + 80.28 The regression analysis of variance (ANOVA) results (Supplementary Table 2 ) demonstrate that the regression model is highly significant ( P < 0.0001), confirming its reliability.

By this criterion, protection was highly significant (Fisher’s exact test, P < 10 −4 ) at any given threshold less than 10,000 CFUs (Extended Data Fig. 8b ), with the IV BCG group showing 90% protection (95% confidence interval: 60–98%) at a threshold as low as 50 CFUs.

Pooled analysis of all trials found a highly significant reduction in recurrence (RR 0·66, 95% CI 0·62 to 0·71; p<0·0001; figure 1 ) and breast cancer mortality (0·67, 0·61 to 0·73; p<0·0001; appendix p 7 ) with chemotherapy plus trastuzumab compared with chemotherapy alone.

Moreover, 40 subjects with samples from two subsequent years showed a highly significant (p<0.0001) increase in cathelicidin concentration from visit one to visit two.

Unpaired t-tests comparing the seronegative and seropositive populations yielded highly significant p-values (p<0.0001) for both the Immunetics® C6 Lyme ELISATM ( Fig 2A ) and the MicroB-plex Anti-C6/Anti-pepC10 Immunoassay ( Fig 2B ).

The analysis of the FSAT results showed that the correlation between the prevalence of asymptomatic carriers and disease incidence reports (both surveillance systems) of the same year was highly significant. “High risk HC 2010” villages had on average six times more asymptomatic carriers than “low risk HC 2010” villages (1.57% vs. 0.24%, P <10 −4 ).

Linear regression of seasonal curve shape against methodological score was highly significant ( r 2 = 0.3, F = 16.9, P < 0.0001, test for normality = 0.2, P < 0.0001) confirming that the tendency to demonstrate seasonal dynamics between the different retained studies depends largely on the degree of statistical or mathematical technical Sophistication of the study.

Based on the results, it showed that the model is highly significant when the computed F -value is greater than the tabulated F -value and the probability value is low ( p < 0.0001), indicating that the individual terms in each response model were significant on the interaction effect.

Similarly, all nonmyeloablative regimens had highly significant reductions in aGVHD risk ( P ≤ .0001 and P ≤ .0003 for grade 2 to 4 and grade 3 to 4 aGVHD, respectively).

In diabetic wound healing, the experimental observation (rate of contraction, epithelization, mean wound healing time) of the study group exposed to 3-7 J/cm 2 dose were highly significant as compared to the control group ( P < 0.0001).

For the constructs with from 2 to 7 rrn operons, the relationship between the lag and the number of rrn operons is roughly linear, with a highly significant slope ( P < 0.00010), for 188 degrees of freedom: P (−17.0 < ρ < −13.6) = 0.95.

The model was found to be highly significant, as evidenced by the results of an F-test, which gave an F-value of 1655.45 ( p < 0.0001).

For MZ twins, the association between twins’ attachment security was highly significant (kappa = .26, χ 2 (1) = 19.86, p < .0001).

The difference in median matching score between successful and unsuccessful treatment lines was highly significant (Mann–Whitney U = 1352, p -value <0.0001; Figure 4 ).

A highly significant difference between the expression levels of the CEA(+) and both the CEA(int) and CEA(-) groups was seen ( p <0.0001).

The difference of 1.02 between the preoperative and postoperative mean score in group B was highly significant ( P < 0.0001).

Moreover, by taking into account the normal and intestinal metaplasia tissue to examine TF expression along the gastric MACS, the increasing trend was shown to be highly significant in both approaches; P <0.0001 by JTOM for both I s and I m scales ( Figure 2 ).