Excerpts

The correlation analysis revealed a highly significant positive correlation between RT-qPCR and RNA-seq data at R-6 h ( r = 0.95 and P = 8.5 × 10 –5 ) and S-6 h ( r = 0.96 and P = 9.8 × 10 –5 ), indicating methodological reliability and supports the consistency of the RNA-sequencing data (Fig. 8 A-H).

The association between rs643892 in LRP5 and LS-BMD was marginally significant ( p = 8.63 × 10 −5 ).

Remarkably, PRRT2 displays a highly significant excess of nonsynonymous (pN) vs synonymous (pS) mutations in Asia (pN/pS = 4.85) and Europe (pN/pS = 1.62) compared with Africa (pN/pS = 0.26; Asia vs Africa: P = 0.000087; Europe vs Africa P = 0.00035; Europe vs Asia P = P = 0.084).

We observed a highly significant increase in adjusted R 2 with the addition of ICA2 to the model ( F (1,507)=15.6, P =8.8 × 10 −5 ).

A paired Wilcoxon signed-rank test confirms that the difference is highly significant, with p = 8.86 × 10 − 5 and a rank-biserial effect size of r rb = − 1.00 .

rettgeri load in flies reared on the low glucose diet ( p = 7.65 x 10 -7 ) and approached significance in flies reared on the high glucose diet ( p = 8.87 x 10 -5 ) and when the data from both diets were combined ( p = 1.49 x 10 -6 ).

To estimate probability of error, we sampled 10 sets of 40 predicted genes and 10 equally-sized control sets, matched by expression; the comparison of the mean bias in the 10 sampled sets showed highly significant difference (p<9e−05; non-paired t test).

Genes that have previously been identified as containing SNPs that are genome‐wide significantly associated with obesity‐related phenotypes (Ensembl; http://www.ensembl.org/index.html ) are labeled with a double asterisk in Table 3 , whereas those that have been observed as highly significant ( P ‐value < 9 × 10 –5 ) have a single asterisk.

The overall effects of strain in the two-way model ( Table 1 ) were highly significant for DCVG ( p = 9 × 10 –5 ), and not significant for TCA, DCA, and DCVC.

The Wilcoxon rank-sum test performed on the additive values revealed a highly significant difference between the P4ex and P4 groups ( p = 0.00009).

A highly significant association was observed (p = 9 × 10 -5 ), with a large effect size (φ = 0.62).

ISX analysis of pure plasma in patients with avidly fluorescent tumors demonstrated a highly significant increase ( p = 0.00009) in PpIX-positive EVs in the post-5-ALA samples as compared to pre-5-ALA samples.

yakuba ( P = 0.0291) and highly significant for D. simulans ( P = 9.044 × 10 −5 ).

Changes in signs and symptoms and verified infection: analysis of individual variables Classification of the highly significant developed GLZ model ( p = 0.000091) was carried out and the percentage of correct classifications of the observed cases was calculated.

In total, 20 of these 37 transcription factors were also enriched in our analysis ( Figure 1 F), and gene set enrichment analysis confirmed that this enrichment was highly significant (normalized enrichment score = −1.8, adjusted p value = 9.1 × 10 −5 ).

In contrast, the partial correlation between body mass and blood 5-HT concentration controlling for blood sample volume was highly significant ( r = -0.495, p = 9·10 -5 ).

Most importantly, we also observed a highly significant correlation with the DFS of patients with stage 1A disease, i.e., with small tumors which had not spread outside the breast ( Figure 3 D, p = 0.000091). 3.4.

Pathways Analysis Gene ontology and pathway enrichment of the top 50 genes revealed that the migraine subjects are moderately significant for the organic hydroxy compound catabolic process (GO:1901616; p -value = 9.12893 × 10 −05 ; adjusted p -value = 0.026108731) and quinone metabolic process (GO:1901661; p -value = 0.000272123; adjusted p -value = 0.038913602) ( Table 5 ; Supplementary Table S2 ).

controls (148 alleles out of 24,758 = 0.6%) was highly significant [ p -value = 9.2 × 10 −5 , threshold = 0.05/ N , N = 1, by Fisher’s exact test (24,610:148 vs. 648:14)], indicating that this relatively common variant has in fact an effect on retinal health.

A repeated-measures ANOVA showed a highly significant interaction between rs12082710 genotype (F 926,608 =4.8; P =9.28 × 10 –5 ) and time on change in HAM-D score.

0.17 g, Figure 3e ), a difference that is highly significant ( p = 9.3 × 10 −5 , two‐tailed Mann–Whitney U test).

For early onset PTSD, the multivariate logistic regression results were highly significant (OR = 2.36, P = 0.000093).

We used a fixed-effects model to validate this observation (“Methods”) and detected a highly significant difference ( P = 9.43 × 10 −5 ) in mean effect between pre-natal ( \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{d

This was again confirmed by a highly significant interaction between the factors “expected time” and “probed time” ( F (1,23) = 22.27; p = 9.482 × 10 −5 , η p 2 = 0.49), or, equivalently, a highly significant benefit for valid compared with invalid trials ( t (23) = −4.71; p = 9.590 × 10 −5 ; d = −0.96).

Conversely, we observed a highly significant difference ( p = 9.485 × 10 − 5 ; paired t ‐test) in self‐described interest when comparing the post‐introductory lecture responses to responses after the practical session with DadApp (mean = 4.746 ± 0.489 SD; Figure 4a ).