Excerpts

An association between cytoplasmic claudin 3 and nuclear Sip1 expression was extremely significant ( p = 0.0000053).

In striking contrast, the susceptible line KW5G321 exhibited severe disease symptoms, with a mean DSI of 75.98%, representing a highly significant difference between the two lines ( p = 5.3 × 10 −6 ) ( Figure 1 A).

Squash bees The effect of trap method was highly significant on squash bee capture (GLMM LRT, X 2 = 24.274, df = 2, p -value = 5.357e−06).

Indeed, only cg00574958 (and related loci cg17058475 and cg09737197) at CPT1A remained significant at the epigenome-wide level ( P < 1.1 × 10 −7 ), while other loci were marginally significant with AUC at P < 5.5 × 10 −6 .

The overlap between ME3 and an aging methylation module found in solid tissues is also highly significant (Fisher-exact p=5.6 x 10 -6 , odds ratio=1.91).

There was a highly significant dependence between the association of states and electrodes based on functional correlations and that based on spatial proximity ( p = 5.6e −6, χ 2 test for independence).

This correlation was highly significant ( P -value = 5.6e−6).

Indeed, when we removed results of studies on open-pollinated families (22 study-trait pairs) in our metadata analysis, the Wilcoxon signed-rank test still remained highly significant (p-value = 5.64e−06), thus confirming the observed general bias of using registered pedigree information to represent the genetic relationships existing between the individuals making up the breeding population analyzed.

After conditioning on the top variant rs4143332 (LD- r 2 of 0.988 to HLA-B*08:01 ), or complement component 4 ( C4 ) expression levels HLA-C*05:01 remained nominally significant (rs4143332: OR = 0.6869, P = 5.662e −6 , SE = 0.0828; C4 expression: OR = 0.68991SE = 0.0865, P = 1.774e −5 ), indicating partial independence from HLA-B*08:01 and C4 .

Together, this change in haplotypes in both Anatolia and the Caucasus is statistically highly significant ( P = 5.7 × 10 −6 , Fisher’s test).

The highly significant correlation between genomic aberrations involving 6p CN-LOH/6p21.3 HD/ BTG1 / ETV6/TP53 and shorter PFS (HR, 5.5; P = 5.8e−6) and OS (HR, 3.7; P = .0075) was also observed in the cohort of 54 prospectively profiled patients at time of biopsy ( supplemental Figure 9 ).

The risk effect on the basis of allele frequencies was highly significant, the pooled analysis showed an OR of 1.11 (95% CI 1.06–1.16; p = 5.8 × 10 −6 ).

The difference between vaccinated and non-vaccinated participants using the Roche S test was highly significant (561.4 ± 431.5-vs.-0.4 ± 0.0, p = 5.80 × 10 −6 ).

Following transformation, SOH revealed highly significant variation among disease classes (F [5,281] = 6.75, P = 5.89 × 10 -6 ) (Figure 1 ).

HYPEST–CADCZ meta-analysis identified a rare variant rs113460564 as highly significant meQTL for a 134-bp distant CpG site ( P = 5.90 × 10 −6 ; β = 3.19 %).

This difference between stages was highly significant (one-way ANOVA for firing rate in 250 ms after cue at early, mid, mature stage of gap task, F 2,638 = 12.2, p = 6.0 × 10 −6 ).

The difference in filopodia numbers was significant between paired data sets showing low and high red-to-green pixel intensity ratios ( t s = 4.13, p = 0.00029), highly significant between data sets showing low and high red pixel intensity ( t s = 5.72, p = 0.000006,) and not significant between data sets showing low and high green pixel intensity ( t s = 1.29, p = 0.207).

The here presented long-term experiments revealed a highly significant rise of local tumour control for normoxic (ambient) (p = 0. 000006) and hypoxic treatment (p = 0. 000030).

The Pearson χ 2 goodness-of-fit test for comparing the total number of observed mutations with the predicted number was not significant for BOADICEA but was highly significant for BRCAPRO ( P = 6 × 10 -6 ).

This difference was highly significant (p = 0.000006), suggesting that early cholecystectomy is associated with a longer recovery period, likely due to increased postoperative drainage and complications (Table 5 and Figure 4 ).

When all of the data collected during the new moon were combined, there was a highly significant orientation towards the azimuth of the moon [ N = 80, Ray. mean bearing = 11.2°, r = 0.38, p = 0.000006; figure 5 a (iii)] and a significant orientation to the magnetic south [ N = 80, mean bearing = 180°, r = 0.22, p = 0.02; figure 5 a (i)].

6a, b ) and were highly significant for both variables for each monkey (7A variance: monkey 1: p < 6 × 10 −6 (Wilcoxon rank-sum test relative to 0 across all pixels in the ROI); monkey 2: p < 2 × 10 −14 ; EV: monkey 1: p < 2 × 10 −21 , monkey 2: p < 9 × 10 −13 ; dlPFC variance: monkey 1: p < 6 × 10 −10 , monkey 2: p < 8 × 10 −8 ; EV: monkey 1: p < 5 × 10 −28 , monkey 2: p < 2 × 10 −12 ).

Chemerin, in particular, demonstrated a progressive increase from the control group to SOP, with a highly significant trend ( p = 0.000006), suggesting a dose–response relationship with SOP severity.

The difference in the date of last detection in the UK for females and males proved to be highly significant (t = -5.2307, df = 39, p-value = 6.033e-06).

We observed a highly significant distance-dependence of the rounding-off behavior: clones farther away from the boundary are rounding off less strongly than clones closer to the boundary (p = 6·10 −6 ).