Excerpts

Using a threshold of mFD > 0.20 mm, 21.4% of ASD participants (124/579) were excluded compared with 11.9% of TD participants (83/698), a highly significant difference (χ 2 = 20.44, p = 6.1 × 10 −6 ).

• IONM signal change strongly predicts worse postoperative outcome, with a highly significant association (χ 2 = 26.89, p = 6.2 × 10 −6 ) This retrospective study of 344 spinal tumor surgeries identifies histology, tumor location, resection extent, and perioperative complications as key predictors of clinical outcome and revision surgery.

The Device-On group, who used the EyeMusic with minimal training were easily able to complete all three parts of the task, with a highly significant success rate of 95.1±8.1% (p<6.3*10^ -6 in comparison to the Device-Off group) for recognition of which door was different, 89.7±11.9% (p<1.1*10^ -5 in comparison to the Device-Off group) for correctly explaining how it was different, and 89.5±13% (p<9.8*10^ -6 in comparison to the Device-Off group) for navigating correctly to the exit (See Fig 5 ).

All correlation coefficients were highly significant (for the natural to unnatural ranking: R = 0.99, p = 6.3140e-06 for M1 and R = 0.98, p = 6.5508e-06 for M2; for the unnatural to natural ranking: R = 0.97, p = 6.5606e-06 for M1 and R = 0.97, p = 6.5677e-06 for M2).

After other variables have been taken into account, the country-level Gini ratio of household income inequality in 1989 has a highly significant power relationship with the number of threatened plant and vertebrate species in 2004 ( P = 6.4×10 −6 ).

For the transition state structure of eIF4AIII bound to RNA, a predefined cluster of RNA helicase-specific residues contacting RNA is highly significant (p=6.4 × 10 −6 ; Figure 3F ).

5 ) identified an enrichment for rare loss-of-function variants in GRN and indeed, with the second strongest enrichment after GRN ( P = 2.2 × 10 −21 ), we observed a nominally significant enrichment of variants in TET2 in the FTD cohort ( P = 6.4 × 10 −6 ).

The slope when including all continents was highly significant (beta = 0.654, p -value = 6.58 × 10 -6 ).

In addition, tests of specific models were also highly significant; the genotypic test for rs634990 gave p<6.59×10 −6 , the additive model gave p<1.45×10 −6 , the dominant model showed increased risk with a p<1.91×10 −5 (OR=2.12, 95% CI=1.50–3.01), and a comparison of the homozygous GG and AA genotypes gave p<3.09×10 −6 (OR=3.12, 95% CI=1.91–5.07).

This asymmetry is highly significant for the 24 pairings in flexor dominated bouts considered alone (average difference .0346±.0075; 20/24>0; p = 6.68×10 −6 ).

Finally, rs1451385 is a borderline significant eQTL (p = 6.7 × 10 −6 ) in subcutaneous adipose tissue in GTEx ( www.gtexportal.org/home ) for AC003090.1 (ENSG00000223561.2), a long intergenic noncoding RNA (lincRNA) with unknown function, located 100 kb from rs1451385.

However, highly significant differences in alleles distribution were found among ER+ (p = 6.8 × 10 −6 ), PR- (p = 4.6 × 10 −5 ), and HER2-(p = 5.9 × 10 −5 ). 4.

As suggested, we conducted a t-test and the difference is highly significant (10-20s after puff, p = 6.8E-6).

In AFR analyses, PLA2G5 was significantly associated with CFR in men (uncorrected P = 2.2 × 10 −8 ), and CAPN2 approached significance in women (uncorrected P = 6.9 × 10 −6 ).

For example, Subcluster002 with 99 nodes had none of the reported cell cycle genes ( Giotti et al., 2018 ), a highly significant departure from expected ( P = 7 × 10 –6 ).

The deviation from the expected number is highly significant ( P < 0.000007).

For OS, only the biopsy variable could be added to the model (because of the problem of singular matrix decomposition), and it did not contribute to OS independently of grade ( p = 0.15), whereas a highly significant contribution of grade was confirmed ( p = 0.000007, Supplementary Table S2 a).

DCN + TL) yielded a highly significant improvement in classification accuracy ( p = 0.000007, r = 0.81).

A total of 75 MTAs were associated with measured phenotypic traits under HNT, of which 24 were highly significant ( p ≤ 7E−06 to 9E−05), 20 were significant at p value = 1E−04, and the rest met a suggestive threshold ( p ≤ 2E−04 to 6E−04) (Supplementary Table S1 ).

Calcium-dependent changes in r 1 observed for Mn L1 and Mn L3 in the presence of BAPTA are 105% and 23%, respectively; both are highly significant ( t -test p < 7 × 10 −6 ).

This resulted in a highly significant increase in the BAX/BCL-2 ratio in GH3 cells treated with 100 μM resveratrol compared to the ethanol control ( P = 7 × 10 −6 ) and the medium control ( P = 4.1 × 10 −6 , Figure 4D ).

Results The analysis revealed significant differential expression of MTFP1 and MTFP2 between tumor and adjacent normal tissues, with MTFP2 showing a highly significant upregulation (p-value = 7.06e-06) and an AUC of 0.698, suggesting its potential as a biomarker.

Although no gene achieved genome-wide significance in the meta-analysis (Bonferroni-corrected p < 2.4 × 10 −6 ), the meta-analysis p-value for the germ cell-specific gene, GGN , was of borderline significance (p = 7.1 × 10 −6 ).

For example, TTN has 5 potential functional synonymous mutations in the case group but does not have a nominally significant p value ( p value = 7.11 × 10 − 6 ), owing to the long length of the gene.

For example, one colocalized SNP for AUD and smoking initiation, rs6589386 on DRD2 , was marginally significant in the single-trait GWAS ( p -value = 7.17E-06) but attained GWS in MTAG ( p -value = 3.58E-10) (Fig. 3B ).