Excerpts

As a result, and despite the limited number of points in the regression, we obtained a highly significant negative correlation ( P = 4.1 × 10 − 10 and R = −0.99), as in the example in Fig. 2d –f.

Yield strength represents the stress required to initiate plastic deformation and is a key indicator of a material’s load-bearing capacity. Statistical analysis ( Table S3b ) again confirmed a highly significant effect of processing method ( p = 4.10 × 10 –10 ), but no significant effect of HEC concentration ( p = 0.925).

Predictive value of the dichotomous score in risk subgroups When applying the cutoff defined in our previous study, PS29MRCdic was highly significant in the prediction of treatment failure (OR, 4.81; 95% CI, 2.95-7.93; P = 4.15 × 10 −10 ).

After this correction, residual SCC dissimilarity was still much higher for natural than for LL-synthetic stimuli and highly significant ( t test, P = 4.17e-10, t = 6.26, df = 7,468).

This enrichment was highly significant (OR, 227.55; 95% CI, 41.43–1,249.71; P = 4.23 × 10 –10 ).

We also performed a Mann–Whitney U -test between the results of the two models that were highly significant, U = 2587.5, n1 = n2 = 56, p = 4.3 × 10 −10 two-tailed, median of the sensor model = 0.77, and median of the baseline model = 0.64.

Similarly, hypomethylation in PD cases can be observed for two highly significant CpGs in immune-related genes cg04772575 in ABCB9 ( p = 4.3 × 10 –10 ) and cg11334709 in C1orf200 ( p = 7.5 × 10 –10 ).

6 d), with the TG association remaining highly significant even after adjustment for these metabolites (p = 4.4E−10).

This difference is highly significant ( P = 4.4 × 10 −10 in a one-tail z test).

This disproportion is highly significant statistically (χ 2 test, P = 4.4 × 10 −10 ).

GWAS Genome wide association analyses of IL-10 levels ( S3 Table ) resulted in one highly significant peak on chromosome 9 in the ACS patient cohort (top SNP: rs676457, P = 4.44*10 −10 ), and another borderline significant SNP on chromosome 6 in the healthy controls (rs11961593, P = 1.80 × 10 −7 ) ( Fig 1 ).

The other two highly significant markers 3173785|F|0–51:A > T-51:A > T on A09 ( -log 10(P) = 9.33) and 3105087|F|0–23:C > A-23:C > A on A09 associated with RE revealed normal monogenic segregation ratio ( χ2 : 4.08 to 4.38, P = 0.111 to 0.129) (Table S9 d).

The results suggested highly significant differences in KDM4A levels between normal mesothelial and MPM tissue specimens ( p = 4.74 × 10 –10 ).

Repeated measure ANOVA demonstrated a highly significant effect of the group factor (good/bad learners: F 1;36 = 85.3, p = 4.9 × 10 −10 ) and the effect of the sex factor (male/female: F 1;36 = 64.4, p = 1.5 × 10 −9 ) on the reaction time.

Increases in the number of active licks across the test sessions was statistically highly significant [ F (1,19) = 133.5, p = 4.9 × 10 -10 ).

In the families, we obtained a highly significant result for the pathway of eight genes for the quantitative trait Q1 ( p = 4.9 × 10 −10 ).

43 The threshold value of −log 10 ( P ) was set as −log 10 0.1/201,817 SNP [ P < 4.96E10-7, −log 10 ( P ) value is approximately equal to 6.3] for identifying true marker–trait associations, which was expressed as the false discovery rate (FDR) test value in the R program 44 ; a true marker–trait association should show a FDR of less than 0.05, and only an FDR of less than 0.01 could meet the criteria for extremely significant association with the traits [ P < 4.96E10-8, −log 10 ( P ) value is approximately equal to 7.3]. 2.5.

For peptides detected in both iTRAQ 4-plex as well as iTRAQ 8-plex labeled form, the median Mascot ions score was 53.9 for 4-plex and 45.6 for 8-plex, and a paired t test was highly significant at p < 5 × 10 −10 .

Surprisingly, results corresponding to the HELPO2 family showed a trend that did not fit with a normal distribution (W = 0.727, P = 5.135 e − 10 , Fig. 1B ).

There was a highly significant correlation between the CT/CT genotype and dilution of pheomelanin (χ 2 = 38.6, df = 1, P = 5.2x 10 −10 ; S2 Table ).

Using the hypergeometric test we determined that this overlap is highly significant (p-value = 5.236594e-10) and would not be expected to occur if the genes were selected at random.

UCK2 expression varied across immune subtypes with a highly significant global difference (Kruskal–Wallis P = 5.26 × 10−10): expression was highest in C4 (lymphocyte-depleted) and lower in C1/C2/C3; C6 contained only one sample and is not interpretable (Fig. 9 C).

A direct comparison between neighbors of the multipliers in the times table vs numerical neighbors to the response in the number line showed that the former were much more frequent, a highly significant result as revealed by a chi-squared test (p<5.29e-010) ( Fig 8A ). 6.

Highly significant similarity ( p = 5.48e−10) was found comparing matched patient primary tumor-PDX to randomly selected pairs (Fig. 6b ).

“Phagosome”, “epstein-barr virus infection”, “osteoclast differentiation”, “viral carcinogenesis”, “proteasome”, and “pathogenic escherichia coli infection” exhibited highly significant enrichment within KEGG pathways. “Protein binding” ( P = 5.58E−10), “cadherin binding involved in cell-cell adhesion” ( P = 1.28E−05) and “poly (A) RNA binding” ( P = .00352416) exhibited highly significant enrichment within the GO molecular function category.