Excerpts

demonstrated a highly significant, low-to-moderate correlation with BMI ( r = 0.249, p = 2.7 × 10 − 10 ).

We found a highly significant correlation between the number of GT n repeats in intron 2 of the TLR2 gene and the polymorphism Arg753Gln (rs5743708) (r = 0.0099038, P = 2.76 × 10 −10 ) (see S1 Fig ).

sentence under the heading “The genetic correlation between height and IQ: Shared genes or assortative mating?” in the Results section is incorrect and should read “We estimate that the additive genetic correlation between height and IQ is .13 in males and .22 in females , and these estimates were highly significant ( χ 2 (3) = 47.4, p = 2.8e-10).”

The log-rank test comparing the overall survival of the two groups was highly significant ( P ≤2.8E-10, Figure 2A ).

The Chi-square statistic was highly significant ( p = 2.93 × 10 −10 ), see Table 3 .

The difference between genders was highly significant ( p = 2.93 –10 ) i.e., men show higher blood Pb levels than women.

The test yielded a highly significant result ( p < 0.0000000003), which strongly suggests that this anatomical region is a low-yield zone for metastatic involvement in patients with intermediate- and high-risk PCa.

Strikingly, highly-biased genes constitute less than one-quarter of the X -linked genes, and this difference from the autosomal genes is highly significant (χ 2 test, P = 3 × 10 -10 ) (Figure 3 , orange bars).

When cells at metaphase and anaphase were pooled, the difference in θ remained highly significant (p = 3.018e-10) ( Figure 2 D, E15.5).

When the endospores were pre‐treated with unconjugated WGA followed by probing them with Anti‐PpWS, there was a highly significant decrease based on CTCF values ( p = 3.09e −10 ; (Schindelin et al., 2012 ) in the recognition of the antibody (Figure 7C ).

The combined influence of tissue and cell type (ie, SI crypts, SI mucosa, and so forth) were also a highly significant predictor of DNA methylation age ( P < 3.1 × 10 -10 ).

This model was found to be highly significant (ANOVA CV p = 3.1 E -10 ) and no regional influence could be discerned.

Comparing pre- and post-treatment conditions, Student’s t -test demonstrated a highly significant difference ( p = 3.13 × 10 −10 ), strongly supporting the hypothesis of treatment-related improvement.

Although the majority of the findings in these included studies did not reach statistical significance, the overall efficacy assessment indicated that SLIT demonstrated effectiveness in pediatric AR patients (SS: SMD=-0.52, 95%CI=-0.75~-0.29, p = 3.17e-10, I2=0%, Egger’s test: p = 0.74; MS: SMD=-0.24, 95%CI=-0.37~-0.11, p = 0.0356, I2=78.68%, Egger’s test: p = 0.34) ( Figure 6 ).

The CMT-GWAS (multitrait) method resulted in more highly significant peaks and a lower FDR than any of the single-trait GWAS (FDR < 0.01; P < 3.2 × 10 −10 ) (Fig. 3 ).

This enrichment is highly significant (hypergeometric test followed by Benjamini–Hochberg FDR correction 33 : expected 7.5 TK, observed 24 TK, p = 3.2 × 10 -10 , FDR-corrected q = 1.9 × 10 -9 ).

The first, on chromosome 16, had a highly significant association (log p = 9.48) and lies in an intron of a cell adhesion molecule, Lsamp (limbic system-associated membrane protein), whose deletion is known to alter behavior in the EPM. 68 , 69 We found a significant interaction ( p = 0.001; Table 1 ), indicating that the effect of the QTL is mediated by the Lsamp gene.

The OR per standard deviation went from 1.75 to 1.44 as age increased from the 40s to 70s and that this trend was highly significant (p=3.44 × 10 −10 ) [ 152 ].

Linear regression analysis revealed a highly significant association between the number of siderophore loci carried by an isolate and its intracellular growth ( P = 3.51 × 10−10).

These two highly significant SNPs were rs1005277 near the ZNF25 gene (OR = 1.45, 95% CI, 1.29–1.62, p = 3.68 × 10 −10 ) and rs12417758 in a long non-coding RNA (lncRNA) gene, RP11-867G23.13 (OR = 1.22, 95% CI, 1.11–1.34, p = 3.66 × 10 −5 ).

We perform whole-exome or genome sequencing of 146 kindreds with sporadic (n = 138) or familial (n = 8) CFM, identifying a highly significant burden of loss of function variants in SF3B2 (P = 3.8 × 10 −10 ), a component of the U2 small nuclear ribonucleoprotein complex, in probands.

Furthermore, highly significant enrichments in biological functions have been observed to be related to the immune system; for example, inflammatory response ( P <3.84E10 −20 –1.53E10 −5 ), immunological disease ( P <8.93E10 −16 –1.65E10 −5 ), hematopoiesis ( P <3.09E10 −14 –4.98E10 −6 ) were frequently encountered.

However, linear regression analysis also demonstrated a highly significant overall correlation between cell loss and the vulnerability module scores (p-value = 3.89e-10), even when the input clusters were excluded from analysis ( Figure 6—figure supplement 1C ).

For the whole group of 253 students, the increase in net score means were 7.85% after SR, and 3.95% after CM; both were highly significant: P < 0.4 × 10 -9 for SR and P < 0.1 × 10 -3 for CM.

Finally, we found a highly significant overlap ( p = 4.08 e –10) of 20 DEGs between Mp spirrig and Atspirrig ( Supplementary Table S5 ).