Excerpts

Under the low ionic strength condition, after 63 days, differences between untreated and sodium periodate-treated saliva samples appeared at the limit of significance (paired sample t -test, p < 0.0021).

Calcifications vary by pathological stage Both lattice parameters (‘a’ and ‘c’ axes) for HAP showed a decreasing trend with increasing pathological stage, with a significant weak negative correlation between the ‘c’ axis and pathological stage (r τ = − 0.284, p = 2.17 × 10 –3 ) (Fig. 4 a,b).

In control pups, separated for 15 minutes per day, gamma power had highly significant correlations with both age (p = 0.0022) and weight (p = 0.0024); gamma in pups separated for 180 minutes per day was not correlated with either factor.

The linear correlation of the in vivo and in vitro measures from brains with both procedures was highly significant (R 2 = 0.709, P = 0.0023; Fig. 3F ).

Conditioning on this common variant rs3817928, the joint test of gene-by-current-smoking analysis for GPR126 remained nominally significant in the discovery ( p -value = 2.4E−03) and genome-wide significant in the replication studies ( p -value = 3.9E−09 in UK BiLEVE and p -value = 9.6E−17 in UK Biobank, Table 3 ).

Statistical analysis revealed the following: channel diameter measurements gave highly significant difference when comparing white-blue (p = 0.0025), white-green (p = 0.0033), blue-red (p = 0.0001) and green-red (p = 0.0001) but no significant difference between white-red (p = 0.0586) and blue-green (p = 0.8017).

Using ANOVA, association of the three factors was highly significant (IL37 SNP (p = 0.0026); M2 (p = 0.0027); M6 (p = 0.0023)).

Response When the 57 EGFR -mutant NSCLC patients of the training cohort were grouped as erlotinib responders and non-responders according to BIM mRNA expression, a clear trend emerged: 88.9% of patients with high BIM mRNA expression responded to erlotinib vs 22.2% of patients with low/intermediate BIM levels ( P = 0.0027).

The interaction between time and treatment effects on urinary free FB 1 was linear and highly significant (p = 0.0027 in the low-dose group and p = 0.0006 in the high-dose group).

PRRX1 exhibited one highly significant correlation with TMEM33 ( r = − 1.000, p = 0.0028), while SLAIN2 showed significant positive correlations with PTPN2 ( r = 0.886, p = 0.033) and TMEM33 ( r = 0.943, p = 0.017).

In the RNA-Seq data, TET3 showed a trend for differential expression in the SGA placentas (DESeq: P = 0.0029; DESeq2: P = 0.00035).

The trend slope changed in a decreasing manner (− 0.798, 95% CI − 1.233 to − 0.363, p-value = 0.001), resulting in a decreasing trend of − 0.622 cases (p-value = 0.003).

Cognitive and clinical correlations between significant TEP amplitude changes and clinical/cognitive measures in patients with schizophrenia A highly significant correlation between TEP P60 amplitude change induced by SICI and the longest span of the Letter-Number Span Test (r = −0.775, p = 0.003, N = 12; α = 0.05/5; controlled by the number of cognitive/clinical measures) (see Fig. 6(A) ) was observed in patients, while no other relationship was uncovered for measures of IQ or executive functioning.

A highly significant hearing disturbance was detected around 24 kHz (42.1 ± 9.1 in +/+ vs. 74.3 ± 8.4 dB in −/− , p < 0.003, Fig. 1 A).

Note that the 3-way interaction remains highly significant (p = 0.003) when controlling for female age (which has a strong effect on miscarriage rates in this population) 20 .

Moreover, accounting for effects explainable by those on generic psychopathology reduced the magnitude of the pre- and postnatal anxiety by stroking interaction effect on irritability by just 12%, and with improved precision this interaction effect on irritability remained clearly significant (p = 0.003).

CpG2 in OVAT is the only site representing slightly significant higher methylation levels in obese than in lean subjects ( P = 0.003).

As shown in Table 2 , high WTAP expression was identified in 44.7% (84/188) of cases with tumors larger than 2 cm and in 28.9% (46/159) of tumors ≤ 2 cm; the between-group difference was highly significant ( P = 0.003).

Total burn incidence showed a trend to increase with increasing grade level (Cochran-Armitage trend test, P = 0.003), but this trend only appeared in females.

Correlations between saliva cotinine levels and number of cartridges/day were highly significant for study groups A and B (Rho = 0.93 for group A, p = 0.003; Rho = 0.95 for group B, p = 0.0004).

Notably, a significant trend was observed across the different CAR categories ( P = 0.003; Table 2 ).

ANOVA results revealed highly significant hourly variability nested in day ( P = 0.003), individual variability nested in pen ( P = 0.001), and at pen level ( P = 0.003) but marginal insignificance between day variability ( P = 0.06).

Whereas the difference did not reach statistical significance in either population alone, it was significant (P = 0.003) when combined controls of both populations were compared to combined patients of both populations.

Linear regression analysis shows that this trend is highly significant for each group, and the magnitude of that drop is also similar for each group: for controls the change in temperatures was −0.173 °C/day (p = 0.003); for doxorubicin −0.274 °C/day (p < 0.001), and for ICT-2552 −0.199 °C/day (p = 0.005).

The risk of developing CKD showed a significant trend with an increase in alcohol consumption ( p = 0.003 for trend).