Barely Significant

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Nevertheless, nine of them (rs541503 ( PHGDH ), rs715 ( CPS1 ), rs272893 ( SLC22A4 / OCTH1 ), rs9393903 ( ELOVL2 ), rs3204953 ( REV3L ), rs603424 ( SCD ), rs174550 ( FADS1 ), rs499974 ( MOGAT2 ), rs7157785 ( SGPP1 )) showed nominally significant association with diabetes in published data from bigger GWAS consortia for type 2 diabetes (up to 110.452 individuals) or exome array analyses (up to 75.670 individuals) of which two (rs174550 ( FADS1 ) and rs3204953 ( REV3L )) were significant after correction for multiple testing by FDR (Table 3 ).
Although there was also a significant trend in the risk of non-pulmonary infectious complications across eGFR categories ( P trend < 0.001 in all adjustment models), the risk associated with eGFR categories was much smaller compared to PPCs; <30, 30 to <60, 60 to <90, and ≥120 mL/min/1.73 m 2 in eGFR categories showed fully-adjusted ORs (95% CIs) of 1.11 (0.99 to 1.24), 0.89 (0.84 to 0.95), 0.91 (0.87 to 0.94), and 1.04 (0.96 to 1.11), respectively, (reference: 90 to <120 mL/min/1.73 m 2 ) (Supplemental Table S2 ).