Excerpts

During the late Iron Age (BCE 640-115; Iberian Period), we observe an increasing trend in average annual HR occurrence that significantly dropped at the time of the Roman conquest of Hispania around BCE 135.

A p value < 0.05 was considered statistically significant (*), p value < 0.01 and p value < 0.001 is considered very significant (**) and extremely significant (***) respectively.

We also found evidence suggesting that the oral microbiota composition changed over time, particularly Streptococcus species, which had an increasing trend between 4–8 weeks in both groups.

Those associations remained nominally significant after controlling for education and upon adjustment for highest household occupational position and potential confounders.

A p value less than 0.05 was considered statistically significant and p < 0.001 was highly significant.

The relative abundance of Acidobacteria ( r = 0.331, P = 0.026), Actinobacteria ( r = 0.481, P = 0.001), Chloroflexi ( r = 0.522, P < 0.001), Armatimonadetes ( r = 0.31, P = 0.038) were significantly closely correlated with ring roads, and Proteobacteria ( r = −0.5, P < 0.001), Bacteroidetes ( r = −0.386, P = 0.009), Gemmatimonadetes ( r = −0.391, P = 0.008) showed a significant negative correlation with ring roads, and Nitrospirae ( r = −0.286, P = 0.057) showed a marginally significant negative correlation with ring roads.

A good example is North America, where the west coast experienced a decreasing trend while on the east coast, water consumption per capita increased.

Nearly all sub-national trajectories show an increasing trend in water scarcity.

Conclusion Understanding the controls on archaeal community structure may be significant in predicting the effects which archaea can potentially have in providing labile nitrogen for developing ecosystems as climate warming occurs.

Highly significant differences in microbial community composition were observed in the phototrophic species C. foliascens and C. orientalis over time (i.e., from t = 0 until the end of the experimental period) ( Table 3A ).

Macrophage-inducible C-type lectin (Mincle) transcripts (Clec4e) were noted in many of the most highly significant innate biofunctions for both CAF01 (brown module) and GLA-SE (red module) ( Supplementary Table 1 ).

2a–c ), a strong trend for upregulation that did not reach significance ( Fig. 2a,b - gray circles in bottom right quadrant) was evident.

We found an increasing trend in the heart rate of short sleepers (≤7 h/night) but without statistical significance.

A decreasing trend of N-P-N amplitude appeared as the flash intensities decreased.

The basal area per unit land area did not present a significant trend; however, the species diversity of woody plants decreased linearly towards the village boundary, which caused a loss of individual density because of severe declines in small saplings compared with adult trees and large saplings in proximity to the village.

Similar to CDOM, the fluorescent components at site S1 showed an increasing trend with depth down to an obvious turning point around the SMTZ depth ( ca. 4.1 mbsf) followed by a gradual decrease to the deeper sediments ( Fig. 3 ).

Cluster 1 has a decreasing trend of gene expression, with enriched pathways in signal transduction and immune response.

Cluster 2 has an increasing trend and is also enriched with pathways for immune response and antigen processing and presentation.

The FVC, MMF, and V25-50 in the G allele subgroup showed a trend of decrease in the A allele subgroup, but the HR and Vm-BA in the A allele subgroup indicated a trend of decrease compared that in the G allele subgroup.

In contrast, when they were fed KD, Ppara −/− mice showed significantly low levels compared with WT mice, while Creb3l3 −/− mice showed a trend of increase ( Fig. 2a ).

A clear trend of micropore size evolution with the irradiation time cannot be distinguished, for this reason CO 2 adsorption was performed taking into consideration that CO 2 is more suitable molecule for the determination of micropores smaller than 1 nm.

Further adjustment for BMI (model 2), the inverse association between height and hypertension risk was similarly found with a significant trend (the highest vs shortest quartile: OR, 0.79; 95% CI, 0.71, 0.88 for men, OR, 0.86; 95% CI, 0.78, 0.94 for women; P for trend <0.001).

Next, we selected the top 10 pathways with highly significant levels, as shown in Fig. 4 .

A significant trend for increased recurrence risk with increasing number of risk genotypes was observed ( P trend < 0.001); compared with patients in the low-risk group, those in the medium-risk and high-risk groups had approximately 3- and 11-fold increased risks of recurrence, respectively (aHR, 2.7; 95% CI, 1.7–4.2 and aHR, 10.9; 95% CI, 6.8–17.4, respectively).

IT injections of 2 μg/10 μl ProTX-II produced a highly significant reduction in phase I and phase II flinching compared to vehicle treated rats ( Fig. 1 ) without any severe effect on motor function ( Supplementary Table 1 ).