Excerpts

Along with the declining prevalence of COPD, a decreasing trend in the prevalence of COPD-related PH was identified from 2009 to 2018 (from 44.8 in 2009 to 33.1 in 2018 per 1000 person-year, p < 0.05).

This impairment was notably mitigated following HFs treatment, with a highly significant reduction in escape latency observed( P < 0.05).

Significant multivariate effects were observed for group (V = 0.0627, F (2,127) = 4.25, p =.016) and age (V = 0.155, F (2,127) = 11.64, p <.001), with motion approaching significance (V = 0.046, F (2,127) = 3.07, p =.05).

These indicators showed an increasing trend from the mild obesity group to the moderate obesity group to the severe obesity group ( P < 0.05).

Even when the regression model was adjusted for probable confounders such as age, stage of recovery, side, and severity of lesion, BUFET was still found to be a highly significant predictor, R 2 = 0.524, with p < 0.05.

WL and AT had highly significant ( P < 0.05) relationships with the CEF.

However, significant associations were presented between free testosterone and locomotor area in model 1 & model 2(0.38, 0.0–0.7, p = 0.04, 0.37, 0.0–0.7, p = 0.04) with borderline significance in model 3 (0.34, − 0.0, 0.7, p = 0.05), respectively (Tables 2 , 3 , 4 ).

Compared with CK, SOC, POC and MAOC contents of B1 and B3 were significantly increased by 2.06 and 3.88 g kg −1 , 0.77 and 1.77 g kg −1 , 1.37 and 3.17 g kg −1 , respectively, showing an increasing trend with higher application rates ( P < 0.05 ).

Two-way ANOVA showed no main effect of locomotion (F (1,7) = 4.05, P = 0.084) but revealed a marginally significant locomotion × frequency interaction (F (1,7) = 5.59, P = 0.050).

The combined SMD was 1.58 (95% CI: -0.01 ~ 3.17, P = 0.05), suggesting that Internet health education may have a positive effect on improving psychological function, but this result was only at a marginally significant level ( P = 0.05).

Notably, residential PSA exhibited a negative correlation with the level of myopia, albeit with marginal significance ( r =-0.189, P = 0.05).

A scatter plot illustrating gene significance (GS) and module membership (MM) within the turquoise module demonstrated a highly significant positive correlation between GS and MM ( r = 0.81, P < 0.05; Fig. 1 F).

One-way analysis of variance (ANOVA) revealed highly significant differences among accessions ( p < 0.05), with coefficients of variation (CV) ranging from 10.28% (exocarp thickness) to 291.36% (petal apex notching).

However, mRNA transcript of ADAM-10 in highly invasive SKOV-3 cells (262.9 ± 13.844) was higher compared to mRNA transcript (23.02 ± 1.566) in OVCAR-3 cells and the difference was highly significant (p < 0.05) (Fig. 3B ).

2 E-G, the mRNA expression of Claudin-1 , Occludin , and ZO-1 in the colon of LOP group showed a decreasing trend compared with those in CK group ( p > 0.05). γ -PGAM treatment enhanced the expression of Claudin-1 , Occludin , and ZO-1 genes at the mRNA levels compared with the LOP group, albeit there was an upward trend observed in γ-PGAL and γ-PGAH groups( p < 0.05 or < 0.01).

Among these 17 SNPs, the only one that was not located in a suggestive or genome-wide significant locus in the discovery meta-GWAS but showed a nominally significant association was rs10490924 at ARMS2 (effect allele/non-effect allele: T/G, Z-score = − 1.96, P = 0.050).

This equates to an odds ratio of 1.2 – 1.4; in other words, the odds of participation is 1.2–1.4 times higher given a 1-unit increase ‘intrinsic (pro-nature) motivation.’ Native Hawaiian ethnicity was also highly significant and positive in two of the models ( β = 1.6 ± 0.6, p < 0.05 at 0.25% payment threshold and β = 2.0 ± 0.7, p < 0.01 at 0.5% threshold), equating to an odds ratio of 5.0 and 7.4, respectively.

Attitude (H6) had a positive and marginally significant effect (β = 0.101, t = 1.963, p < 0.05), indicating that favorable evaluations of forest policy contribute to higher support intentions.

When ADHD traits at 2 years were included in the model the overall regression was statistically significant ( r 2 = 0.640, F (2,79) = 68.44, p < 0.001), ADHD traits at age 2 significantly predicted ADHD traits at age 3 (β = 0.798, p < 0.001), and Prohibition scores at age 2 showed a trend-level predictive association to ADHD traits at age 3 (β = 0.035, p = 0.050).No other predictive associations from EF performance at 2 years to 3-year autism and ADHD traits were found.

High TPR expression was significantly associated with improved 28-day survival (log-rank P = 0.0048), whereas high ERN1 expression showed a trend toward poorer survival (log-rank P = 0.05) (Fig. 5 G–H).

In contrast, logistic regression analysis conducted on males (as detailed in Table 4 ) demonstrated a positive trend between α-Klotho levels and hyperlipidemia ( P > 0.05).

Statistical significance was defined as a P-value < 0.05, while P < 0.01 was considered highly significant, and P > 0.05 indicated no statistical significance.

Pearson correlation analysis revealed that out of the 12 soil factors examined, 6 of them showed highly significant correlations with EMF (Fig. 5 , P < 0.05).

In the univariate analysis, smaller FCD volumes showed a statistical trend of being correlated with higher AI values after controlling for age at MRI (Spearman’s correlation: − 0.48, p = 0.05, Fig. 2 B), whereas other epilepsy-related or lesion-related features were not related to AI values (Table 4 ).

A higher proportion of males was observed in the MAFLD group, although the difference was of borderline significance ( P = 0.05).