Barely Significant

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SSPE (isolated or multiple) were 8.8% (CI 7.1–10.5%) of all diagnosed PE with prevalence ranging from 2.0 to 15.9% of diagnosed PE, with only three marginally significant differences on pairwise comparisons.
Moreover, these same effects appear to be present in KO Slc1a1 -/- mice and are an equivalent magnitude; 2) Slc1a1 +/- mice display reduced thickness of DMPFC, particularly layer V, which is also consistent with neuroanatomical findings in schizophrenia; 3) Slc1a1 +/- mice exhibit a lower ratio of reduced to oxidized glutathione (GSH/GSSG) as well as a possible trend for increased oxidative DNA damage in the brain; 4) There appears to be compensatory or downstream effects in the brains of Slc1a1 +/- mice, that lead to significant changes in the expression of genes and pathways involved in synaptic and cognitive functions; 5) There are robust changes in the expr