Excerpts

On the other hand, a significant trend toward an increase in cancer mortality from group 1 to group 4 was observed, and this result was unchanged after exclusion of the first three years of follow-up (data not shown).

A decreasing trend of single point exposure vs. time since last dose for simvastatin was observed, but no such trend was observed with other short half-life medications, such as oxycodone.

In this work we have been able to highlight the disproportionate vulnerability of migrants to acquire HIV-TB compared to nationals, a clear trend in the majority of the studies included.

A trend toward significance between worse kidney function and apoB was shown in diabetes patients without CVD, however, this association weakened after further adjustment [ 17 ].

The pilot study found a positive trend towards a reduction in the need for hospitalization and intravenous fluid treatment for the participants in the intervention group compared with those in the control group ( Table 2 ).

Its incidence and mortality have shown a decreasing trend over the last several decades.

The increase of AAPC during 1998–2015 was of borderline significance for these tumor types in men.

In this research, compared with GSM, the AUCPDC showed a statistical association with CHD ( p = 0.05) ( Table 5 ), but the correlation is barely significant.

These results suggest that part of the associations cannot be detected in GWAS [ 47 ] and therefore, the genetic differences between subpopulations may prove to be highly significant when searching for the genetic determinants of a disease or physiological trait.

The TE with MMC led to a statistical trend of reduction in mean IOP total and mean fluctuation total regardless of gender, form of glaucoma, lens status, history of TE in the fellow eye and postoperative needling.

Nevertheless, while this Borraginaceae family provides bees with more sucrose, glucose and fructose, the relationship between sucrose and hexoses (fructose + glucose) may be significant [ 12 , 13 ].

Pairwise differentiation was highly significant between these colonies and several others, and well within both the range at which structure can be discerned using microsatellites [ 95 ] and that of other seabirds in which structure has recently been reported [ 96 – 98 ].

This tendency did however not reach the statistical threshold for the time spent in the odour relative to the non-odour quadrants (Z time = 1.04, p time = 0.30) but was only near-significant for the travelled distance (Z distance = 1.72, p distance = 0.085).

These features can also be selected a priori, for example in myopathic studies, decomposing raw electromyographic signals into frequency domain information often results in highly significant differences between healthy and myopathic patients, increasing the accuracy when diagnosing neuromuscular disorders [ 27 ].

Within the cave population, where the average nucleotide diversity of cave-downregulated transcripts was 75% that of the cave-upregulated transcripts, a highly significant difference, whereas within the spring population the nucleotide diversities of cave-downregulated and cave-upregulated transcripts was virtually identical.

Bamboo was found to be highly significant in red panda distribution as bamboo was recorded in nearly 89% of the sign plots, with density ranging from 0.21 to 31.81 bamboo culm/m 2 and an average value of 6.01±5.59 culm/m 2 (non-parametric bootstrapped Welch t-test: -7.80±0.96, p ~0.00.

Although both the IFNγ ELISA and ICS assays showed a significant trend towards improved inter-site comparability at higher measured responses, the effect was stronger in the former assay where inter-site CVs were below 10% at the highest measurable responses.

Therefore, in case of borderline significant results, a realistic model of evolution should be used, and phylogenetic uncertainty accounted for.

Although detailed epidemiological data on IDA in CD are limited, recent studies suggest that IDA may be significant in both CD children [ 10 , 11 ] and adults [ 12 ].

The hypothesis whether CAD preferentially classifies malignant over benign cores was tested with a chi-squared test, which revealed independent classification of benign and malignant biopsy cores, albeit with a slight trend towards the classification of malignancy, P 0.06 ( Table 3 ).

Additionally, because sleep quality showed a trend to significance and a strong effect size for the third night it is speculated that the treatment with the platinum harmonized textile needs a longer duration for potential major and significant influences on the performance parameters as well as systemic parameters like CK.

From 20.1 to 17 Ma, both EM 2 and the δ 18 O curve showed a decreasing trend, implying that global warming during this period weakened the EAWM.

We acknowledge that, as with many analyses, we might have a few false-positive results and that the results should be interpreted with care, especially when p values are close to the level of significance.

In summary, our MD simulations show a clear trend for the Aβ40 triple-fibril investigated.

This last observation is interesting because it suggests that plasma TNAP activity or TNAP vesicular shedding might be regulated by an interaction between age and diet, however this single highly significant observation might has also occurred by chance considering the large number of parameters investigated.