Nevertheless, a recently published systematic review and meta-analysis, comprising of eight original articles with a total of 21,064 participants and 2,053 CHD events [ 33 ] reported a positive association between leptin and incident CHD after adjustment for age, sex, lipids, blood pressure, and BMI, although the association did not quite reach statistical significance [ 33 ].
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The “rounded tip” trait is indeed significant on this axis, but is also more marginally significant on axes 2 and 4, and has thus a more complex intrinsic importance.
This corresponded to a highly significant increase of ART coverage for PLWHA at the early latent infection stage from less than 10% to 30%, 35% and 40%.
Among other individually found genomic alterations, TP53 mutations (p=0.07), mTOR gain (p=0.07) and PTEN overexpression (p=0.08) have a marginally significant negative impact on OS.
1990), there has been an increasing trend in the SOI (CRU, climex.knmi.nl) and dominance of La Niña conditions [ 59 ], which coincides with the period of high precipitation in northwest Australia in the last two decades ( Fig 6 ).
In our report, we found an increasing trend over time of non-B subtype HIV infections in Barcelona.
a positive trendgold
Ten glaciers exhibit negative surface albedo trends (-0.0005 to -0.005 yr -1 ) during the period 2000–2011, whereas TLMKL has a positive trend (0.0006 yr -1 ) in the Karakoram area ( Fig 3 ).
Using a dominant model, the CC genotype of rs4822983 ( CHEK2 ) had a marginally significant protective effect compared to the CT and TT genotypes.
The correlation between 18 F-FDG and Ki-67 was highly significant in TETs, significant in GISTs, moderate in lung, breast, bone and soft tissue, pancreatic, oral, thoracic, uterine, and ovary cancers, average in brain, esophageal and colorectal cancers, and poor in head and neck, thyroid, gastric and malignant melanoma tumors.
The data consistently showed that none of the subjective scores were sensitive to the effect of order or duration ( S2 Table , none of the eight effects of interest reached significance or even reached marginal significance).
There was an increasing trend within the conditions.
[ 21 ] An observer bias means that disagreement between observers is not attributable to chance, and that there is a significant trend for overestimation or underestimation by certain observers.
More importantly, contrast sensitivity loss for 0.5 cpd showed a trend with thinning of the neural rim.
The HDRS score showed a trend towards an improvement at follow-up (with a moderate effect size); a dysthymic disorder, evaluated by the SCID-I, was found in only one patient at follow-up, vs. 5 at baseline.
a strong trendgold
Mice injected with scAAV9-Syn-Nudt7 or scAAV9-Syn-Nudt7cyt showed a similar reduction in motor coordination at 9 weeks of age; however, mice with neuronal overexpression of Nudt7cyt exhibited a strong trend towards a reduced performance also at 17 weeks of age.
The number of high F ST variants is significantly higher for intron than that for the genome-wide background, whereas that for pseudogenes was marginally significant compared to the genome-wide background.
Embryos incubated in hypoxia starting at 28 h after fertilization showed an increase in Hif-1α protein after 4 h of hypoxia, and a 4 h hypoxic incubation, started at 52 h after fertilization, resulted in a more than two-fold increase in Hif-1α protein concentration, which was highly significant.
Overall, our results reveal an interesting trend: RankSVM achieves better Mean NDCG@10 than RKHS regression for many different hyper-parameter settings.
Interestingly, however, there was a marginally significant negative correlation between participants’ LGVT reading comprehension score and the difference value of alpha frequency band power between baseline and test condition.
Interestingly, although no evidence of lag-1-sparing following an emotional distractor emerged in the group analysis, roughly half of the participants showed a trend towards better performance at lag-1 than at lag-2.
a slight trendgold
Although a slight trend towards increased tumor take of sarcomas transplanted from NCF1* / * mutant mice was observed, this difference was not significant and did not support a role for NOX2 produced ROS in immune editing of MCA induced sarcomas.
A highly significant increase (300% higher than the controls) in cellular ROS (measured by using the probe DCDCDHF) was observed after the treatment with 1mM Fe 2+ or with Fe-Cu combinations (1 mM-10 μM; 1 mM-50 μM).
While expression of Lhb and Cga showed a trend toward being reduced in Foxm1 null embryos, this was not statistically significant.
a clear trendgold
The response of this species over time does not appear to follow a clear trend, with some areas increasing and other decreasing in different years ( Fig 9 ).
A recent study using the data of 13 mountain stations of Nepal (1980–2009) reported that only the maximum and mean temperatures are in an increasing trend without any changing trend of minimum temperatures [ 69 ].