Excerpts

We found that the presence of Ssk-FB4s was always associated with stronger resistance against viral, bacterial and fungal infection in all datasets 71 – 73 : the comparison reaches marginal significance in one set with female flies subjected to bacterial infection ( P = 0.06, Supplementary Fig. 19 ), and significance in another two sets with flies subjected to fungal infection ( P = 0.002 and P = 0.02, respectively).

As with the HBB donors, the majority of differentiated cells were CD19 + lymphoid and CD33 + myeloid cells, with a strong trend towards more genome editing within the CD33 + population (55.8 ± 12.0 vs. 22.3 ± 11.2; p = 0.06, two-tailed t-test) (Supplementary Fig. 4d, e ).

When including both vmPFC effect on k g and aIns effect on k l in the choice model, the regression with NPM was only marginally significant ( p = 0.06), meaning that residual error was roughly flat (Fig. 3b ).

12g ), with Panc 05.04 cells showing a nonsignificant trend in the same direction (1.12 fold, P =0.06; t-test; Supplementary Fig. 12g ).

Notably, patients achieving CR exhibited markedly higher T cell activation immune scores post-treatment compared to those PR patients, demonstrated by a trend toward significance ( P = 0.06, Fig. 5c ).

Furthermore, a statistical trend in the interaction effect was also found F(2, 26) = 3.15, p = 0.06 in which post-hoc comparisons revealed that only in the opsin condition animals at phase 20 cm kept significantly increased defensive distances compared to phase 10 cm as well as to phase none ( p < 0.05 and p < 0.001) respectably, while no differences were found within the control group.

Total developmental time from egg to adult emergence ranged between 23 and 31 days and was shorter on smaller hosts (ANCOVA: F 1,109 =8.11, P <0.005, r 2 =0.05, n =112) and shorter in broods developing from larger numbers of eggs (ANCOVA: F 1,109 =32.48, P <0.001, r 2 =0.22, n =112); the interaction between these main effects was marginally nonsignificant (ANCOVA: F 1,108 =3.62, P =0.060, n =112).

The [S]-rHDL group showed a trend towards a decrease of 17% compared to the oral statin group (Mann-Whitney U test p=0.06, Fig. 4c ).

The results for females were marginally significant for all villages ( N =126, r =−0.14, Student’s t -test P =0.06) and inland villages ( N =29, r =−0.27, Student’s t -test P =0.08), but not for coastal villages ( N =97, r =−0.1, Student’s t -test P =0.14).

During the reward delivery event, the cOFC did not exhibit a significant trend (t(4) = − 0.29, p = 0.78), but the pACC exhibited a marginally significant effect (t(4) = − 2.55, p = 0.06).

However, during the GFP period, a clear gradient emerged: VPD sensitivity did not significantly change in good years ( p > 0.10) but showed a statistically significant improvement in bad years ( p = 0.01), and a marginally significant increase in normal years ( p = 0.06) (Supplementary Fig. 18 ).

In the Baby Animals task, generalization accuracy was significantly associated with age, β = 0.01, SE = 0.001, t (180.6) = 8.90, p < 0.001, 95% CI [0.008, 0.012], and showed a trend toward a significant association with verbal intelligence, β = 0.003, SE = 0.002, t (180.0) = 1.90, p = 0.060, 95% CI [−0.0001, 0.007].

Interestingly, NOD mice treated with BIBO3304 displayed a significant decrease in glucose levels (Placebo, 5.35 ± 0.11 mM; BIBO3304, 5.03 ± 0.09 mM; * P < 0.05), which is associated with a strong trend to increased insulin levels (Placebo, 73.31 ± 9.42 pM; BIBO3304, 103.2 ± 11.87 pM; P = 0.06), indicating that β-cells in a T1D environment are responsive to the inhibition of Y1 receptor signaling.

We found marginally significant effects (repeated measures analysis of variance (RM ANOVA), offline: F 2,22 = 3.22, P = 0.06; online: F 2,22 = 2.72, P = 0.09); however, the differences were small and the opposite direction for on- vs. offline stimulation.

An analysis of variance revealed differences in the proportion of cells in S-phase, G2/M-phase and G0/G1 in Shh creERT2/C mutant versus Shh +/C littermates that approached significance (F (2,8) =4; P =0.06).

Combining these regions into a meta-ROI, we observed that the AD+LB+ group exhibited faster glucose hypometabolism than the AD+LB− group at a statistical trend level ( p = 0.06, Fig. 3C ).

Immunofluorescent staining with IL17 and HIF1A antibodies showed a trend for more IL17 + cells ( p = 0.06) and higher HIF1A expression ( p = 0.09) in DFU-Healers (Supplementary Fig. 7g–i ).

In this part of the task, 45 , 46 , the Cyfip1 +/− rats continued to respond to the original S + over successive sessions, while the WT began to switch their choices to the new S + (a 2 × 2 ANOVA revealed a main effect of SESSION ( F (3,39) = 3.67, p < 0.05) and a GENOTYPE × SESSION interaction ( F (3,39) = 3.76, p < 0.05), where a main effect of GENOTYPE was marginally significant ( F (1,13) = 4.32, p = 0.06)).

The quantification results revealed a statistically significant positive correlation between TET1 and GCLC protein levels (Pearson r = 0.705, P < 0.001), and a positive trend was observed between TET1 and GCH1 expression (Pearson r = 0.331, P = 0.060).

The meta-analysis of the FUT2–ABO interaction effect in the discovery stage revealed a borderline significant interaction (OR = 1.08 (95% CI = 0.99–1.17), P = 0.06), with significant evidence of heterogeneity between the two discovery studies (heterogeneity P = 0.002).

Comparison among correlation coefficients showed a nearly significant difference between rapamycin and placebo arm in serum NfL ( p = 0.0608); the difference was less pronounced for pNfH ( p = 0.1429).

The high PSPI1 H-score approached significance ( p = 0.061) in the matched TMA-internal but not in the TMA-validation TMA ( p = 0.36).

Reco BM was on average 13±4% larger than Reco EC (marginally significant at P =0.061).

The median and interquartile range (IQR) for blood collection from severe (5 [IQR 4–7] days) versus mild-moderate groups (4 [IQR 2–6] days) approached significance ( t -test p = 0.061).

Rnaset2 −/− mice showed a trend towards reduced alternation rates (31.7 ± 11.8% vs. 39.2 ± 9.7%; p = 0.061) at the age of 4 months.