Excerpts

Although limited by small sample size, ML-DS enrichment scores were higher in progressive compared to conventional TAM samples, with a near-significant difference (one-sided t-test, p = 0.055), supporting the notion that the ML-DS transcriptomes may help delineate TAM cases at higher risk of progression.

Despite limited statistical power given the use of duplicates, these results showed marginal significance (One-sided t test, anterior start P value = 0.055, posterior middle P value = 0.09).

2i ), a marginally significant increase in approach speed (EYFP: 3.59 ± 0.28; hM4D: 5.24 ± 0.67; P = 0.0555, unpaired t -test) (Fig. 2j ), an increase in the mean duration of individual investigation (EYFP: 3.04 ± 1.16; hM4D: 7.258 ± 1.446; P = 0.0404, unpaired t -test) (Fig. 2k ), and a less percentage of stretched postures towards stimulus mice (EYFP: 86.22 ± 5.90; hM4D: 49.86 ± 6.71; P = 0.0006, unpaired t -test) (Fig. 2l ).

Administration of anti-Ly6G antibody significantly suppressed CCRK-induced PMN-MDSC accumulation in liver ( p < 0.01), leading to a borderline significant reduction in HCC tumorigenicity ( p = 0.0555; Supplementary Fig. 5e, f ).

Previous study showed that mucin-degraders (family Prevotellaceae) were enriched in patients with depression and anxiety 47 , and a further subgroup analysis of present study also supported a near-significant increase of Akkermansia in unaffected controls with antidepressant ( n = 5, P value = 0.056) when comparing to those without (Supplementary Fig. 9b ).

In comparison, the combined explained variance by soil properties (soil pH, C/N, and moisture) had a marginally significant negative relationship with latitude for soil fungal communities (Adj R 2 = 0.16, p = 0.056) (Fig. 6a ).

A marginally significant effect of condition, F (1,15) = 4.31, p = 0.056, η 2 = 0.22, revealed higher hit rates when earn colors were presented first relative to when save colors were presented first, specifically at shorter onsets (8 ~ 38), F (1,15) = 4.81, p = 0.044, η 2 = 0.24, where onset information was limited (left panel, Fig. 4a ).

Although not reaching the level of conventional statistical significance, two neuropeptides that showed a strong trend toward differential expression were RYa ( F 2,9 =4.033, P =0.056) and myosuppressin (MYO; F 2,9 =3.611, P =0.071).

Expected parasitism based on a binary regional food web was a marginally non-significant predictor of observed parasitism ( z =1.9, P =0.056, with a partial regression coefficient of 1.9 (s.e.=0.99) for binary data ( Supplementary Table 8a ), compared with 2.3 (s.e.=0.84) for quantitative data ( Supplementary Table 3 ).

A 6 (SNR) × 2 (group) mixed ANOVA on arcsine-transformed 22 accuracy revealed that older adults were less accurate than young adults irrespective of SNR ( F 1,30 =19.48, P <0.001), and accuracy increased with increasing SNR in both groups ( F 5,150 =399.10, P <0.001), with a marginally significant group × SNR interaction ( F 5,150 =2.21, P =0.056, Fig. 1b ).

1 ), a significant increase in sputum CD14 - CD16 - cDCs, and a strong trend ( p = 0.056) for an increase in CD1c + cDC2s, the dominant subset of sputum CD14 - CD16 − cDCs, was associated with human patent infection (Fig. 2D ).

Drug concentration showed a trend towards an effect on peak viral load and on AUC viral load ( p = 0.056 and p = 0.074, respectively, Fig. 3e, f ), suggesting that high concentrations could be associated with a reduction of viral load, with a nonlinear relationship.

In addition, fox-urine exposed animals showed a trend of more freezing than non-traumatized animals (left, p = 0.056, lemon and air groups combined).

This difference reached statistical significance in LNs (cervical and mesenteric) and gut tissues (colon and ileum), while PBMCs showed a trend approaching significance ( p = 0.057).

CT-179-treated tumors showed a trend to decreased p-OLIG2 (p = 0.057), consistent with disruption of OLIG2 dimerization, and significantly reduced p-RB, indicating an overall decrease in proliferation (Fig. 5A ).

The mean of the individual changes (Δ = V7–V1) in each of these metabolites was also significantly different between the NR and placebo groups, with the exception of NADP + , which, however, showed a strong trend after multiple testing correction ( p = 0.057; Supplementary Data 6 ).

2c ) but showed a trend for larger litters compared with native backcrosses (native x immigrant F1-F4 pairs; t = 1.9, p = 0.057, 95% CI [−0.18, 2.02]; Fig. 2c ) although not statistically significant.

Using the genes that contributed most to the enrichment of this upregulated gene set ( n = 48 genes), we built the first principal component (PC1) of their VAT bulk expression and identified a negative trend (rho = −0.242, p value = 0.057) between PC1 of the VAT bulk expression and the adipocyte diameter in RYSA (Supplementary Note 1.7 , Supplementary Data 43 ).

The interaction effect of stimulation status × type appeared borderline significance in ODD, f = 3.10, p = 0.057, η 2 = 0.09.

The methylation level between the benign and advanced-stage cancer groups was significantly different ( p -value = 0.011), while the difference between the benign and early-stage cancer groups was borderline significant ( p -value = 0.057) (Fig. 2e ).

Expression of WNT11 correlated significantly ( p = 0.014) and FZD8 showed a trend ( p = 0.057) with increased biochemical recurrence (Supplementary Fig. 8b ).

MBP staining within CD11b+ cells showed a strong trend towards less internalized myelin in plKO males at P15 compared to littermate controls ( p = 0.0571) (Fig. 6e ).

sensitized MAP comparison was nearly significant ( p = 0.0574).

The angular distribution of diurnal acrophases for H3K9Ac peaks proximate to such sites differed from those for peaks distant from such sites ( W =4,572.6, P =0.0136, n =664 samples), and the difference in angular distribution of seasonal acrophases showed a trend toward significance ( W =3,643.2, P =0.0576, n =664 samples).

Stromal CD8 + T cells showed a similar tendency but with marginal significance (stromal CD8 + T cells, P = 0.058; Fig. 6d ).