Excerpts

Results obtained with both tobacco and Arabidopsis showed a trend similar to those reported by NERNST in chloroplasts, namely, a redox shift toward reduction of the NADP(H) pool upon dark-light transition (Supplementary Fig. 16 ).

It is reasonable to expect that these databases will be most accurate for binary alloys, rather than more complex compositions, and so in the first part of the work described in the following, we have focused on binary alloys in an attempt to minimize one possibly significant source of uncertainty.

All 5 CpG positions included in “HCC-detect” and “HCC-spec” are significantly more methylated than in either healthy controls, chronic hepatitis B or both or non-HCC cancers ( CCNJ is nominally significant when compared to healthy controls and significant against chronic hepatitis B).

However, there was a somewhat significant lower alcohol use and higher fraction of smokers in the HCC groups (Table 2 ).

A clear trend of period lengthening effects was observed in WT in the presence of 1–100 μM AZD4573, while ∆ brd-8 shows even a stronger dose effect on period changes than WT, especially 100 μM at which concentration ∆ brd-8 becomes completely arrhythmic, while WT is ~ 6 h longer than seen under no drug treatment (Fig. 7a ).

KS tests for uniformity with respect to the distribution of the temporal centroids of the trajectories in each temporal column were conducted, controlling for a family-wise error rate (FWER) of 1% according to Bonferroni’s inequality 39 such that 108 columns were identified with a p -value >0.01/409, indicating a highly significant degree of temporal non-uniformity.

According to current observations, the soil moisture content in the Arctic does not yet show a negative trend and remains on average close to saturation.

Thus a clear trend in rate could be visualised corresponding to a specific polymer parameter, t .

In the quality evaluation process of ground improvement, although the subgrade strengthened by piles is equivalent to a set of strata, the GPR response characteristics of equivalent strata are completely different from those of strata without pile, and there may be significant differences between the GPR response characteristics of defective piles and complete piles (Fig. 1c, d, e ).

The correlation of PACpAInt-Comp with RNA tumor and stroma components was highly significant in the BJN_U validation cohort and substantially improved in the spatially matched validation cohort BJN_M (Suppl Fig. 3b ).

While the NS of all Asian reservoirs combined has a decreasing trend (−0.18 ± 0.01%/20 yr), the NS value of the pre-1999 reservoirs shows a significant increase (1.30 ± 0.01%/20 yr), which suggests that the overall reduction of NS is attributed to the post-1999 reservoirs.

Although there was a clear trend towards further reduction of endoscopic scores in mice that received TIF-Gel-TAC, this was not significant (Fig. 4e ).

An increasing trend in the f ̄ C D H E is found in 48 out of the 50 cities (the lone exceptions being Buffalo and Chicago).

The calculated unit size was not different from zero during individual increments 2–4, although with an increasing trend, and attained significance during decrement 5 (~5 pA, p = 0.0005, different from 0, two-tailed one sample t test) and when the data points from decrements 4 and 5, which had similar mean values, were combined ( p = 0.0017).

Plotting the relationship between ATAC-seq data (promoter-TSS region) and RNA-seq data for PPARα target genes showed a highly significant correlation (Fig. 4e ), but a significant correlation was not seen for target genes of HNF4α (Fig. 4f ).

The out-of-plane p y character becomes slightly significant only for E > 0.6 eV, and the contributions from the La-Te1 block is negligible.

Although these photochemically driven deformations can be quite significant in the extent of bending or curling, the processes of amplification of the strain caused by the photochemical reaction at a molecular scale to macroscopic bending are known to be kinetically inefficient, and such processes generally are not thought to qualify for actuating applications 27 .

7a , as the irradiation time increased, the conversion of the material gradually increased and eventually became greater than that of the UV-cured material, while the tensile strength of the material showed a trend of increasing and then slightly decreasing with increasing irradiation time, Fig. 7b shows a more detailed stress-strain profile.

One study including 13 cancers found four pairs with marginally significant correlations 11 .

In the subgroup analysis, the addition of bevacizumab showed a trend of improved efficacy (Hazard Ratio [HR] = 0.63 [0.47–0.87] versus 0.74 [0.53–1.04] for patients without bevacizumab), suggesting that adjuvant anti-angiogenic therapy combined with immune checkpoint inhibition warrants further investigation.

Both groups showed a trend toward a continued increase in the per-animal average SHM of RABV-G-specific MBCs, from 2 weeks post boost to 12 weeks post boost.

Furthermore, the nucleation density presents an increasing trend with the temperature (Supplementary Fig. 10k ), indicating a close dependence on thermodynamics.

A linear regression of each percentile likewise reveals that JJA is the only season that displays a significant trend in waviness across any part of the distribution (Supplementary Table 1 ).

Given the strong linear relationship between sinuosity and the GBI, one could expect a positive trend in Greenland blocking simply by virtue of increasing waviness under AA.

The rising South-South trade showed a mitigation effect on the global EEBT with an increasing trend, but the contribution was still relatively small compared with the mitigation effects of the North-South trade.