Excerpts

However, with the widest prior ranges (60 and 80), the relative risk estimates associated with NA and HA stalk were less precise, with credible intervals overlapping 1, suggesting borderline significance.

When the mean incubation period increased from 1 to 2 days, some borderline significant parameters—such as the effect of HA stalk on susceptibility and NA on infectivity—shifted slightly above 1 in the upper value of the 95% credible intervals.

In line with knock-down by siRNA, treatment with the calcium channel blocker drug nicardipine 55 or AOX1 inhibitor drug raloxifene 56 also showed a trend towards increased HDR when combined with M3814 (Fig. 3h ).

This correlation was highly significant for Q-TOF data (Pearson’s p ≪ 0.0001), but not statistically significant for Orbitrap data ( p = 0.0588).

Combined knockdown showed a trend toward further reduction, but BAX depletion alone had the strongest impact.

Podocalyxin, a negatively charged sialylated glycoprotein involved in polarization 17 and basal organization 18 , exhibited stable protein expression and an increasing trend in the HF group (Fig. 3c, d , Supplementary Fig. 3a ).

Lastly, we emphasize that not all lectins followed the simple rule of preferring higher surface-availability, as lectins such as PHA-L actually showed a trend of preferring their binding motif to be somewhat buried (Supplementary Fig. 10e and f ), potentially indicating additional interactions with distal sequence contexts.

5g ), resulting in a nonsignificant trend towards greater nearest neighbor distances in synapses with ongoing fusion.

This manipulation simulated the thermal landscape in wheat fields, whereby the temperature at different heights of wheat plants differs greatly at midday, showing an obvious trend of higher temperature at the upper part and lower temperature at the lower part 71 , 72 , which provides a temperature gradient for the aphids to regulate their body temperature by moving downward.

Similarly, AphPHYA-B1-GFP driven by the ApuPHYA promoter ( Pro ApuPHYA-B2 ::AphPHYA-B1-GFP ) showed a marked trend toward increased submergence-induced protein accumulation compared to Pro AphPHYA-B1 ::AphPHYA-B1-GFP (Fig. 5k and Supplementary Fig. 5b, c ).

There is a clear trend for premolar size reduction from early Homo to H. erectus , but the premolars of DAN5/P1 are small even in comparison with early African, Georgian, and Indonesian H. erectus .

In sharp contrast, the scattering pattern for path 2 displays an unexpected trend: products from low-partial-wave collisions exhibit forward scattering, whereas high-partial-wave collisions predominantly yield backward scattering.

5C ), a proxy for addition of sediment-derived melts 42 , 68 , defining a positive trend.

These increases were preferentially more medially distributed and showed a trend toward the anterior portions of the striatum.

However, transcriptomic investigations have consistently identified approximately the same number of genes being up- or down-regulated during seedling or cotyledon de-etiolation, and none have demonstrated a clear trend in gene upregulation 8 – 11 .

While TMX NPs showed a trend of improvement over the free drug (Supplementary Fig. 13B ), the p -value did not reach statistical significance.

1 A shows that the total adoption rate in Washington is around 1.9% in 2022, and the incremental adoption rate presents an increasing trend from 2010 to 2022.

Since the associations at this locus were highly significant, we looked for variants that might affect protein structure and function.

Other inflammatory genes such as Tnf, Il6, Il10, Cxcl2 and Ifnb also showed a trend towards higher expression levels in the lungs of RPC mice at this time point.

We found that the PNS group showed a trend toward lower incidence rates of HAEC and total complications across all subgroups.

Latitudinal analysis revealed a clear trend: RWHPC decreases with increasing distance from the equator and increases with greater rainfall depth.

The result showed that the total serine level of NRF1 was significantly increased, but the total threonine phosphorylation level showed a decreasing trend under DNA damage (Supplementary Fig. 6 a, b).

sQTLs that were also eQTLs First, GTEx variants were filtered for those that were both nominally significant sQTLs (.v8.sqtl_signifpairs.txt) and nominally significant eQTLs (.v8.egenes.txt) in the same tissue (GTEx browser) .

Sedimentary archives from the ECS reveal a striking divergence: while δ 13 C org exhibits an increasing trend, 10 of 13 cores show coherent declines in δ 15 N from the early 1900s to present, with an average rate of −1.09 ± 0.48‰ per century (Supplementary Figs. 8 and 9a–b ).

Conversely, a weak trend between MW and toxicity suggests that heavier compounds are less toxic.