Barely Significant

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In primates, we find a significant trend in U1 motif distribution around orthologous P/E elements similar to that detected in rodents (Fig. 4e ) but no difference in PAS density (Supplementary Fig. 9 ), probably due to the low sequence divergence between human and macaque and the resulting lack of power 36 .
Although we observed considerable variabilities in rejection ratio in some of sexual behavior assays using these mice, presumably due to viral injection surgery-associated stress, control groups in which saline was intraperitoneally injected before the assay still showed a trend of ESP22-induced increase of rejection ratio.