Barely Significant

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The Potential Intermediary or Storage Role of DNICs by GST Enzymes The role of GSTs in detoxification may be significant in NO metabolism, given that the binding of with DNICs directly to GSTs results in a markedly increased half-life (4.5–8 h) [ 210 ] and a significantly increased half-life than “free NO” (i.e., 2 ms to 2 s) [ 211 ].
Behind the main constituents, the other terpenoids, including mono-, sesqui-, and diterpenes, might be significant inhibitory agents, singularly and/or synergistically, of inflammations according to the previous in vivo and in vitro studies including carrageenan-induced rat paw [ 60 ].