Excerpts

In the present study, we found that in comparison with the healthy control group and topical treatment group, moderate-to-severe AD patients treated with dupilumab had the shortest COVID-19-associated disease course, although p -value (0.046) from the dupilumab treatment group compared with the topical treatment group was close to the limit of significance, which may be explained by the small sample size.

In this study, we could not draw the conclusion that dupilumab treatment remarkably improves COVID-19 symptom severity score because the p -value (0.059) was borderline significant, probably, also due to the small sample size.

However, in the present study, disease progression in FVC decreased with marginal significance after rituximab treatment, while disease progression in DLco did not change after rituximab treatment.

Introduction The prevalence of pelvic organ prolapse (POP) ranges from 40 to 50%, with a 3 to 12% symptomatic rate and an increasing trend [ 1 , 2 ].

aeruginosa sputum density was more commonly reduced with TIP than placebo, but an increasing trend of resistance to tobramycin compared to baseline was observed in the group of patients treated with TIP (although this trend was also found in the placebo group).

The authors showed a trend towards an earlier sputum culture conversion in the study group, although this was not statistically significant.

In that study, we followed patients up to 12 months after ureteroscopy and reported a decreasing trend in infection-free rates from 88% at 3 months to 71% at 12 months; additionally, we highlighted the relationship between stone recurrence and UTI recurrence in this group of patients.

Most participants showed either a negative trend or no trend in the baseline phase.

comparing different revascularization strategies for ISR in diabetics showed that local drug delivery by DEB or DES was markedly better than POBA in preventing TLR; however, treatment with DEB showed a trend of less development of MI than did treatment with DES [ 93 ].

During the study period, the number of patients requiring surgery and hospitalisation due to e-scooter related injury demonstrated an increasing trend. 3.2.

Interestingly, prehabilitation group showed a significant trend for lower INTERMACS classification at last month’s previous HT.

Considering that the deep NMB group showed a trend of less paresthesia and sensory change, significant results may be obtained if a larger number of participants were investigated, or a longer follow-up was conducted.

FMN showed an increasing trend over time, with the highest value in the MP group and lower and similar values in the MP-pH 7.6, 7.8, and 8.0 groups.

showed a trend towards a longer hospital LOS following NMP graft preservation, however, their results do not reach statistical significance (17 cf. 12 days, p = 0.119).

Three associations were supported by strong meta-analytic evidence, endorsing highly significant results with no suggestive bias.

The membrane-oxygenated group demonstrated a decreasing trend of oxygen consumption starting after 2 h of machine perfusion ( Figure 3 b).

The marginal significance of the treatment effect over time on echocardiographic parameters, regardless of the specific drug administered, may be secondary to the insufficient statistical power of our study. 5.

Smoking presented a nearly statistically significant independent prognostic factor for survival with a p -value of 0.052.

The study showed a trend towards a higher rate of cardiac deaths in the CTO PCI arm in 4-month follow-up [ 38 ] and in 3-year follow-up, to a significantly higher incidence of cardiac death (6.0% vs. 1.0%, p = 0.02) with the trend in all-cause mortality (12.9% vs. 6.2%, HR 2.07, 95% CI 0.84 to 5.14; p = 0.11) [ 41 ].

When patients were categorized into four groups according to the quartiles of average heart rate, there was a significant trend toward a higher average heart rate with diabetes, chronic lung disease, high heart rate at admission and discharge, decreased LV systolic function, and low prescription rate of beta-blockers and renin-angiotensin-aldosterone blockers at discharge.

In the current subsample of 80 children with one-year follow-up data, MCP produced a significant improvement in children’s social skills and a statistical trend for a reduction in reactive aggression compared with CP.

terminating it after LAAO, as well as a positive trend towards being survival-free regarding all-cause death, systemic stroke, CE, and major bleeding provided by this strategy [ 17 ].

[ 30 ] described a marginally significant difference in the MMSE scores between healthy controls and mild HCV asymptomatic patients.

While Klotho levels of the recipient and donor before transplantation may be significant, Klotho levels measured after transplantation are not associated with decline of renal function in our cohort.

A statistically significant reduction in pain was observed at any time point, and quality of life measured at six months showed a nonsignificant trend toward increase.