Excerpts

Additionally, LPO showed an increasing trend along with the ischemia duration; however, the change was not significant.

It was highly significant when the test scores were grouped dichotomously between high and low risk to be related to HT, T2DM, obesity, and CR. 4.1.

further reported that delirium related to COVID-19 had a highly significant correlation with neurological comorbidities and dementia.

Overall, there was an increase in UV-Q and UV-Q/AC, while UV-Q/EFW showed a decreasing trend ( Figure 2 ).

Interestingly, we report, for the first time, that although the BCVA improvement remained significant at 24-month FU, there was a significant trend towards a worsening of visual acuity with time.

The multivariate model shows a highly significant temporal relationship with uveitis grading, which decreased by 1.97, 2.28 and 2.19 at 3, 12 and 24 months, respectively ( Table 4 ).

There is, however, a trend towards significance with each follow-up visit, with the upper limit of the 95% confidence interval at 24 months being only 5.9 μm thicker than the baseline measurement is, while the lower limit is 119.7 μm thinner than the baseline measurement is.

Conclusions: A clear trend towards decreasing apelin concentrations as birthweight progressively increased was identified.

Nevertheless, due to the highly significant associations observed between CVD and OD as well as between pulmonary diseases and OD, it is reasonable to assume that there are specific pathophysiological processes connecting CVD, pulmonary diseases and OD.

Two recent studies using Cerament in DFO have reported using systemic antibiotics between 4 and 6 weeks, indicating a possible trend that clinicians are now becoming more confident limiting systemic antibiotic duration with antibiotic impregnated Cerament instillation.

We have seen a decreasing trend in both wound ooze and ‘Cerament burns’ (skin erythema from leakage of Cerament) amongst our patients, which we attribute to the learning curve associated with its use.

Furthermore, the minimum SpO 2 (%) at diagnosis was significantly correlated with the PSQ scores (%), social and school results (with a positive trend), and ADHD index (with a positive trend) at follow-up but was negatively correlated with physical abilities.

There was no correlation between %EBMIL and either positive answers ( r = 0.08) or negative answers ( r = −0.14), but there was a positive and a negative trend, respectively.

On the one hand, only a few patients are affected (1–4% after kidney transplantation) [ 10 ], so the additional costs are hardly significant due to the small number of patients.

Indeed, the presence of coronary artery disease (CAD) has been identified as having a highly significant and independent predictive role in the achievement of the recommended LDL-C goals [ 33 , 34 ], which may suggest more stringent monitoring and management of LLT to achieve the recommended therapeutic goals in patients with an established CVD.

Depression is a public health problem with an increasing trend in prevalence [ 4 ].

This showed a trend toward improved effectiveness with the higher dose, but given the number of patients in this analysis, it did not meet statistical significance. 3.1.6.

A multiple linear regression analysis showed that there was a moderately significant effect between women’s age, marital status, week of pregnancy, physical activity before pregnancy, physical activity during pregnancy, attending childbirth classes, STAI (X-1), STAI (X-2), and PSS-10.

Although not statistically significant, there was an observed trend for an increased prevalence of moderate–severe gingivitis with an increasing number of toothbrushes per day.

At the eight-month follow-up, the between-group difference remained significant (mean difference of 4.59 points) on the MCS, whereas that on the CBS was borderline significant (mean change of −0.14 points).

In consistency with our hypotheses, the results showed significant between-group differences, with the family intervention showing more benefits compared with psychoeducation on our primary outcome measures, including improvement in mental-health-related QoL at the two-month and eight-month follow-ups, and on reducing caregiver burden at the two-month follow-up, and borderline significance at the eight-month follow-up.

Despite some variation in the frequency of these modalities between single years, logistic regression did not show a significant trend over time for the frequency of CT, neurological examination, SSEP, or EEG (see Table 2 ).

Recently, a phase II RCT of Filgotinib (a Jak1-inhibitor) in pSS failed to reach its primary endpoint, consisting of a composite outcome measure; however, a sub-analysis of the trial showed a trend toward clinical efficacy in patients with severe disease [ 91 ].

This may have prevented us from analyzing the data in a different way, possibly leading to other factors that may be significant in SDM in this population.

In the multivariable model 1, TyG index showed a trend for a lower probability of ENI (categorical variable, vs. lowest tertile, medium tertile OR 1.00, 95%CI 0.63–1.58, highest tertile OR 0.59, 95%CI 0.38–0.92, overall p = 0.022; continuous variable [per unit increase], OR 0.73, 95% CI 0.56–0.94, p = 0.015).