Excerpts

There was a mild trend between the first 2 groups ( p = 0.22).

There was no statistical difference between the two treatments, but the bi-layer membrane showed a slight trend towards a lower score than the PCL membrane ( p = 0.220). 2.3.

However, we observed a positive trend in the surface defect closure rate in cells stimulated with 100 ng/mL of CTRP8 (1.26 ± 0.17-fold; p = 0.23).

The expression of miR-204-3p was significantly higher in serum exosomes from patients with mucinous cystic neoplasm than patients with IPMN ( p = 0.02, p = 0.007), while there was a marginally significant difference between mucinous cystic neoplasm and PC patients ( p = 0.24).

Although Child’s B and C patients showed a trend to higher myostatin levels, these were not significantly different of those observed among Child’s A patients (KW = 2.83; p = 0.24).

Homogeneously Expressed Proteins and Genes within the Tumors and Associated Pathways Proteins with a stable expression (i.e., had a low CV) within minimum four tumors ( Section 4 ) ( n = 49) showed marginally significant (one-sided Fisher’s exact test, adj. p < 0.25) enrichment for signaling processes such as PI3K–AKT–mTOR signaling, EPH–ephrin signaling, oncogenic MAPK signaling and signaling by Rho GTPases ( Figure 3 a, Table S5 ).

There was no difference between ischemic retinae and those treated with the VEGF inhibitors (beva: p = 0.75; rani: p = 0.27), although a slight trend to fewer Bax + cells was observed in the ranibizumab-treated group in relation to the ischemic group ( p = 0.27).

Not distinguishing patient clusters, critically ill patients who survived the SARS-CoV-2 infection showed a trend to higher IL10 concentrations ( p = 0.28, Figure 1 H).

Furthermore, in those samples that specifically had p53 R248 missense mutations, there also showed a trend toward a higher expression in R72 homozygous tumors (fold change = 7.8, p = 0.3) ( Supplementary Figure S6 B).

No significant difference in CD9 presence was found between stages ( p = 0.67), nor was there a significant trend ( p = 0.31) in the current data.

Moreover, a poor ECOG performance status showed a nonsignificant trend for predicting shorter PFS (ECOG PS 0 versus ECOG PS ≥ 1, 4 months versus 7 months, HR = 0.585 (0.358–0.956, p = 0.32).

A decreasing trend in the proliferation of eMSC was observed when they were exposed to hypoxia in the presence of DAPT ( Figure 5 B, n = 6, p = 0.34) and underwent less rounds of self-renewal when compared to normoxia ( Figure 5 C, n = 7, p = 0.07).

No significant differences could be observed in terms of ciliation, although a slight trend towards increased ciliation could be seen in mutant cultures ( p = 0.35).

Notably, PR expression was lower in EOCs than in nonadjacent normal epithelial tissues; however, its overexpression in EOCs showed a trend toward poor DFS ( p = 0.384; Figure 1 D). 2.2.

After miR-542-3p transfection, the mRNA level of LEF1 showed a trend of being elevated ( p = 0.4204) and that of TCF7 was significantly increased ( p < 0.05) ( Figure 7 A).

Additionally, the mobility parameter in male NM does not appear to follow a clear trend, with there being no significant difference between controls of NC grade 2 (68 yo) and NC grade 3 (73 yo) ( p = 0.453542).

A negative trend between the appendicular skeletal muscle mass parameter (ASSM) and the expression of PTGER4 has been noted (r = −0.224, p = 0.484).

Its radioprotective activity was absent only in the region of 1/18 LD 10 (18 mg/kg), and in the range of 1/12–1/4 LD 10 (27–80 mg/kg), the effect of T1082 was highly significant ( p = 0.49–0.85).

In addition, overweight was associated (borderline significance) with higher LEP promoter methylation; β = 0.02045 and p -value = 0.536 ( Table 3 ). 3.

The distribution of patients according to the rASRM classification did not show a significant trend ( p = 0.751).

However, the density of the 88 kDa band was slightly lower in the LPS group compared to the control group (U = 0.90, p = 0.063, n = 17) ( Figure 11 D), but with only borderline significance, and no differences were observed between the control and the TNF-α-treated groups (U = 137, p = 0.80, n = 17) ( Figure 11 D).

Compared to the minimally affected 2 MBq group, the 1 MBq group had significantly lower survival ( p = 0.0042), although it narrowly missed statistical significance compared to the 3 MBq group ( p = 0.808).

Knockdown of CCNE1 showed an increasing trend in the proportion of the sub-G1 phase compared with that in the control group at 48 h and 72 h (9.5 ± 4.6 vs. 8.5 ± 5.4, p = 0.819; 19.2 ± 11.5 vs. 8.4 ± 2.5, p = 0.186, respectively), and a decrease in the S phase (22.1 ± 2.6 vs. 25.8 ± 4.4, p = 0.283; 18.8 ± 3.3 vs. 24.0 ± 1.4, p = 0.066, respectively) ( Figure 4 ).

Treatment with Src kinase inhibitors 4-amino-5-(4-methylphenyl)-7-(t-butyl)pyrazolo[3,4-d]-pyrimidine (PP1) and 4-amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]-pyrimidine PP2 tended toward significance ( p = 0.9093 and 0.1935, respectively) but displayed variation between replicate wells.

The top four highly significant (−log( p -value) = 20–31) pathway categories affected by both CBS deficiency and stroke subtypes were LXR/RXR activation, acute phase response signaling, FXR/RXR activation, and coagulation system ( Figure 2 C).