Excerpts

26.3%), and the additive model indicated a significant trend of increasing risk with increasing T allele number (OR = 1.50; p = 0.044).

While rs429358 exhibited a moderately significant association with PACG in the recessive model ( p = 0.044), this significance did not survive Bonferroni’s correction for multiple testing (0.05/2 = 0.025).

The haplotype analysis, considering a minimum frequency in either group of at least 2%, showed a presence in the overall population of 7 haplotypes with comparable prevalence between cases and controls, with the exception of haplotype CAAC (rs2071590, rs2844482, rs2234694 and rs4880), which exhibited a significant trend toward a protective effect in migraine (OR = 0.49 (95% C.I.: 0.25–0.98), p = 0.044) ( Table 3 ).

The comparison between ES and adult brain tissue indicated that miR-124 showed modest significance as overrepresented in brain ( P = 0.044), suggesting that the miRNA may be more important in the mature brain tissue than neuronal-differentiating ES cells.

The GWA of mtDNA-CN based on CHARGE Consortium and UK Biobank cohorts ( n = 24,622; median follow-up 4318 days) found a nominally significant association between mtDNA haplotypes and the overall non-external mortality ( p = 0.044) [ 31 ].

In more detail, a highly statistically significant difference was found when comparing the first age class with both the second (adjusted p < 0.001) and the third one (adjusted p < 0.001), while the difference between 18–59 and ≥ 60-month patients was marginally statistically significant (adjusted p = 0.044). 2.3.

The interaction between ultrasonic power and incubation time had a somewhat significant effect on the DPPH free radical scavenging rate ( F = 4.8668, p = 0.0446).

C) included seven studies [ 9 , 19 , 20 , 25 , 26 , 27 ] and showed a borderline significant association with PD risk (OR = 1.22, 95% CI: 1.00–1.48, p -value = 0.0446; I 2 = 79.2%; Figure 3 A).

PD-L2 mRNA expression was statistically marginally significant and moderately positively correlated with BTLA protein expression (Spearman’s ρ = −0.24, p = 0.045).

Additionally, there was a higher frequency of elevated aTG in TS patients, although this difference was borderline significant ( p = 0.046).

A marginally significant difference in DFI according to AR status was shown in total ( p = 0.0468, more favorable DFI for AR-positive group than AR-negative group); however, the difference in DFI between AR-positive and -negative groups was even clearer in the ERβ-positive group ( p = 0.0285) but was lost in the ERβ-negative group ( p = 0.7734, Figure 4 ).

Higher PANSS scores were significant predictors ( p < 0.001) of aggression, while lower levels of HDL cholesterol, due to correction for multiple testing, contributed to the model with marginal significance ( p = 0.047).

Although one-way ANOVA indicated a borderline significant main effect in the DH (F (2,17) = 3.675, p = 0.047), post hoc testing did not confirm any significant pairwise differences between the control and experimental groups.

Moreover, the (E)CpG4 unit 3′ of this epigenetic boundary showed the greatest overlap in methylation values between the controls and PM ranges in males, with intergroup comparison showing a decrease in methylation of marginal significance in the PM group compared with the male controls ( p = 0.047).

However, there was a borderline significant difference in creatinine concentration ( p = 0.047) ( Table 2 ).

Furthermore, tumor volume (borderline significance with p = 0.048) and PHI ( p = 0.0009) remained as independent factors in multivariable analysis to predict a biochemical recurrence ( Table 6 ) beside the known pathological data pT stage and Gleason score.

Despite the lack of differences, a linear effect was observed at the limit of significance ( p = 0.048).

At 400 MPa/5 min, biofilm levels were lowest overall (PET: 0.34 ± 0.08; PP: 0.37 ± 0.05; SS304: 0.42 ± 0.07) and ANOVA indicated a marginally significant surface effect ( p = 0.0482).

In contrast, at pH 8.4, 8-Br-cGMP increased I-TASK1 evoked at 0, +30, and +60 mV barely significantly ( p = 0.049, two-way ANOVA: pH effect, F(1, 4) = 7.84) and only by 16%, 14%, and 11%, respectively ( Figure 3 (B1,B2); 0 mV, p = 0.002; +30 mV, p < 0.001; +60 mV, p < 0.001, two-way ANOVA followed by Fisher’s PLSD; n = 5).

Albumin was borderline significant (r = 0.110, p = 0.049), while TMAO was not significantly correlated. 2.4.

We observed a borderline significant association for the putative effect of genetically predicted MG liability on AD in the weighted median model (OR = 1.01, 95% CI: 1.00–1.02, p = 0.049) [Supplementary Table S7] , which is not convincing.

Among three isoforms, only the expression of the MEFV full-length (i1.2) transcript was borderline significant (patients vs. controls, mean ± SD, −0.34 ± 1.1 vs. 0.32 ± 0.79; p = 0.049) while for the transcript lacking exon 2 ( MEFV -d2), p -values exceeded the significance threshold (patients vs. controls, mean ± SD, −0.1 ± 0.79 vs. −0.45 ± 0.65; p = 0.08) ( Figure 2 a–c).

JA in infected Col-0 at 8 h was lower than in C24 at 8 h, reflecting the delay in the response in Col-0, although the difference was only marginally significant ( t -test, p = 0.049).

The difference between CON + SAL and KA + MI was only marginally significant (T = 2.23, p = 0.049, DF = 10), whereas the difference between the KA + MI and KA + SAL groups was not significant on 2-tailed test (T = 2.19, p = 0.053, DF = 10).

Table 1 also shows that MITF expression was higher in UM with chromosome 6p gain, which was associated with a better prognosis, albeit with a borderline significance ( p = 0.049).