Excerpts

Furthermore, a positive correlation between the 5-year mean IGF-1 SDS and the duration of GHRT was nominally significant (r = 0.421, p = 0.036).

Here, a borderline significant negative correlation ( p = 0.0360) was observed between the fold change decrease in NRON and the TTVR ( Figure 3 B), suggesting that the drop in NRON expression might have some value in predicting the time to viral rebound.

Considered individually, miR-320a-5p showed a statistically significant AUC score, while as miR-21-3p did not reach statistical significance (AUC = 0.647, p = 0.037 and AUC = 0.453, p = 0.058, respectively).

While the rs2336691 A allele were associated with a higher risk of developing CAD ( p = 0.037); borderline significant association in both additive and dominant models [OR additive = 1.632 (1.030, 2.583), p = 0.037 and OR dominant = 1.599 (1.020, 2.507), p = 0.040].

Associated lipid indices (TyG, TyG-BMI, TyG-WC, and TyG-WHtR) showed that TyG had a highly significant p -value (<0.0001), followed by TyG-WC index ( p = 0.038).

MR pleiotropy residual sum and outlier (MR-PRESSO) test identified 5 outliers for IBD, 1 for RA and 2 outliers for vitiligo ( Table S10 ), whereas exclusion resulted in a nominally significant association for vitiligo (OR, 95% CI: 0.827, 0.691–0.989), p -value = 0.038; Figure 4 a).

We previously detected a slightly significant ( p = 0.0385) correlation between DNA methylation and age in patients with PD, but not in subjects with AD or VaD [ 35 ].

Only a moderately significant interaction was found between XRCC3 Thr241allele and more PYS ( p = 0.039).

Thyroid Function As reported in Figure 2 , mean TSH at TP0 between the euthyroid and hypothyroid groups showed a small and marginally significant ( p = 0.04) difference.

For offspring whose diet was changed at weaning, there was a moderately significant three-way interaction between PS, maternal diet, and sex (F (1, 127.4) = 4.26, p = 0.04) ( Figure 10 A).

A borderline significant interaction was detected ( p = 0.04), with an increased concentration of mercury measured in the feces of mice exposed to MeHg HD and SeMet concomitantly ( Figure 2 ). 2.3.

It should be emphasized that in this model of LPS-induced inflammation, the increase in the IL-6 level is robust ( Figure 8 B, LPS + vehicle), and SM administration to LPS-challenged mice additionally showed a trend toward increased IL-6 expression ( p = 0.04), while dexamethasone administration slightly but significantly ( p < 0.005) reduced the IL-6 level in the serum of experimental animals ( Figure 8 B).

This should be interpreted with caution because the statistical data suggested that this was a weak correlation (small correlation coefficient, Rho = 0.18) with marginal significance ( p = 0.04).

Postoperative recurrence-free survival was not significantly correlated with CHST4 expression ( Figure S7 ), but survival after recurrence showed a trend similar to that of postoperative survival ( Figure 6 B), with a significantly better prognosis in cases with strong CHST4 expression ( p = 0.04).

As for ipsilateral coordination, Kruskal-Wallis statistical analysis carried out on r -values between all 6 data groups (i.e., on one control group and two post-drug groups—for the 1st and 2nd EMG burst in Tri activity—and each of them for both left and right animal side), showed an overall weakly significant result (KW(5) =11.59; p = 0.04).

A rare CRHR2 variant (rs3779250-risk allele-C) has been reported in Japanese patients with MDD [ 21 ], and a previous study in Belgium reported an MDD-risk variant with borderline significance ( p = 0.04) [ 54 ].

A marginally significant difference was observed when comparing AD patients with MCI (χ 2 = 3.84, df = 1, p = 0.04), while no other pairwise differences were detected ( Figure 5 a).

The difference in BDNF transcripts was comparable to the results obtained from LCM-captured cells, and the applied statistic test (described in Section 4.6.1 ) indicated a marginally significant difference ( p = 0.0406) between the two neocortical neuron populations.

The REML model showed no significant association ( p -value = 0.95, β = 0.02; 95% CI [−0.55, 0.58]), but the fixed-effect model indicated a marginally significant negative association ( p -value = 0.042, β = −0.0035).

ETS1 protein abundance was significantly lower ( p < 0.05) in the control and 1 ng/mL treatment groups, while the nSS2 cells only showed marginal significance ( p = 0.042) for 10 ng/mL vs. 1 μg/mL ( Figure 3 A).

The effect of irisin treatment was highly significant for the immobility time in the TST ( p = 0.042) and the FST ( p = 0.002), the entries and time spent in the open arms ( p = 0.043 and p = 0.041, respectively), and the total stretched-attend posture ( p = 0.045) in the EPM.

No significant correlations were found between the visceral or subcutaneous TLR7 expression and systemic leptin, adiponectin, C1q/TNF-related protein 3 (CTRP3) or CRP levels, while a borderline significant negative correlation was observed between the TLR7 expression and progranulin serum levels (rho = −0.215, p = 0.043 for subcutaneous and rho = −0.202, p = 0.057 for visceral adipose tissue TLR7 expression).

However, despite the borderline significance, our results suggest an atheroprotective role of small LDL (beta = 0.339, p = 0.043).

A Student’s t -test revealed a highly significant difference regarding tracer uptake between the osteogenic group and the corresponding control group (μ-PET p = 0.043; activimeter analysis p = 0.012).

The reduction in CoQ 10 concentrations in blood did not reach statistical significance. α-tocopherol concentrations were reduced to 82.1% ( p = 0.043), 79.6% ( p = 0.022), and 72.0% ( p = 0.037) in blood, plasma, and PLT in comparison to the healthy men ( Figure 3 A–C). γ-tocopherol concentrations in the blood, plasma, and platelets of the infertile patients were also lower than those in the healthy controls; however, these declines did not reach statistical significance ( Figure 3 D–F). 2.4.