Barely Significant

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highly significantqualifiedgold
However, while the association with age per year (OR = 1.078 [95% CI 1.059–1.097]), male sex (OR = 3.174 [95% CI 2.081–4.480], diabetes (OR = 1.930 [95% CI 1.399–2.662] and the PNPLA3 148M risk variant (OR = 2.083 [95% CI 1.492–2.909] remained highly significant in multivariate analysis ( Table 3 ), the association with each of the SAMM50 minor alleles was lost when the regression model included the PNPLA3 I148M risk variant, suggesting that variation of SAMM50 rs3827385 and rs3761472 are linked to the risk factor PNPLA3 148M. 2.5.
Although the great majority of these women was lean (median BMI of 22.3 kg/m 2 ; 20.3–24.8 interquartile range), BMI data showed a significant trend to higher values from the north to the south of Italy, while no significant difference was observed between mothers residing in rural or urban areas. 2.2.
When we selected all samples having stronger MFAP5 expression (score 2 and 3) both in the stromal and epithelial compartment ( n = 9), and compared them to the rest of the samples ( n = 99), a slight trend toward worse OS in the first group was visible; however, it was not statistically significant ( Figure 4 ). 2.4.
The lack of a significant trend in pulse wave velocity and augmentation index measurements, as surrogate markers of aortic stiffness, would suggest that there is no clinically relevant impact following the administration of iron in non-dialysis-dependent CKD or atherosclerosis secondary to an increase in selectins.
Although the two-miRNA panel consisting of miR-1 and miR-133 achieved good discriminatory performance for CAD in T2DM (AUC = 0.752), the diagnostic value for miR-1 (AUC = 0.802) alone was even better than for the miRNA panel, probably due to the only marginally statistically significant AUC for miR-133 [ 301 ].