Excerpts

The results illustrated that the conductivity of membranes was increased by raising the temperature from 30 to 90 °C, although pristine SPEEK membrane showed a decreasing trend by increasing temperature.

Analysis of the mostly highly significant putative upstream regulators was based upon an activation z-score and statistically significant ‘overlap p -values’ in IPA ( p < 0.01).

On the contrary, the injured animals treated with vehicle at 35 dpi showed a trend towards a slight improvement that was highlighted by a decrease in significance with respect to the control group in the paw reaching task that would be induced by the rehabilitation therapy itself.

They found that the microorganisms, metabolites in GCF, and clinical data combined showed a clear trend, and clinical data regarding periodontitis could be reflected in the shift of the oral microbial community and the change in metabolites in GCF.

While no clear effect of HA was observed at the time point studied, the exogenous addition in control cells showed a trend for the reduction in the percentage of the CD24 + /CD44 + population in MDA-MB-231 cells ( Figure 2 D).

CM has an incidence of 0.2–0.8 per million [ 3 , 6 , 7 ], with an increasing trend [ 3 , 8 ].

ERG analysis showed that the group of P4 ZF6-DB injected animals resulted in highly significant preservation of retinal responses compared to sham injected controls (a- and b-waves in scotopic condition; Figure 1 D,E; photopic responses, Figure S1B ).

The imidazolium-based ILs showed a decreasing trend of the granulocyte-macrophage percentage, while phosphonium-based ILs tended to reduce the percentage of lymphocytes and appear to cause larger changes to leukocyte distribution.

Congruent with this, our preliminary results on stem cell characterization in SGPL1 −/−M.Ex1 cells showed a trend towards stem cell marker depletion ( Figure 6 g), indicating a possible contribution of SGPL1 to stemness.

THP1 M2 IH EVs significantly increased MRC-1 and showed a trend for increasing IL10, but also increased the expression of the pro-inflammatory gene CXCL10.

Discussion The therapeutic approach contrasting advanced melanoma, the most aggressive cutaneous tumor, has recently taken an encouraging trend, due to the development of new targeted and immunotherapies [ 13 ].

Although clearly requiring investigation in human embryos, such processes are likely to be significant regulators of successful embryogenesis and allow for the integration of MT data with the detrimental effects of Bmal1 knockdown on embryogenesis.

The CS1 and CS2 genes in both cultivars showed a trend of initially decreasing and then increasing throughout fruit development which coincided with the change of CS enzyme activity ( Figure 5 ).

The sugar–acid ratio (TSS/TA) of both cultivars generally exhibited an increasing trend during fruit development, while TSS/TA of ‘yellow passion fruit’ rose significantly faster than that of ‘purple passion fruit’ in later developmental stages ( Figure 1 D). 2.2.

The study showed five taxa with a decreasing trend from NAG to IM to GC (two Saccharibacteria , two Porphyromonas, and one Neisseria ).

There was no significant difference in pediatric cell migration after treatment with Stx-1, however a clear trend towards a delay in wound healing was visible.

In our study, full-field VEP measurements showed a trend towards attenuation of the VEP signal upon ocular hypertension, yet did not reach statistical significance, perhaps due to limitations in detection.

Thus, rapamycin-injected mice were smaller and weighed less than DMSO-injected mice—an effect that was highly significant ( Figure 4 D).

CMC2.23 at 20 μM showed a trend for reduced TYR and MITF but the levels did not reach statistical significance ( Figure 3 F).

The IFX t1⁄2 substantially decreased with increased platelet count in HR and RR individuals, so the contribution of platelet-mediated elimination became highly significant at high platelet counts in these individuals.

Besides gyrA and parC , which passed our p -value cut off (5.21 × 10 −7 ), we could find mutations in less-studied genes involved in modifying target enzymes, such as gyrB and parE , as well as in the genes involved in alterations of permeation, such as acrB , ompC , mdtK ( norE ), and mdfA , which did not pass our p -value cutoff but were mildly significant ( p -value around 5 × 10 −3 ).

Then, we applied association analysis between variants and antibiotic resistance phenotypes to reduce high-quality to highly significant variants.

Amongst all studied proteins, only the expression levels of NPM1 and phospho-c-Myc (Ser62) showed a trend towards an increase in both BRAF-mutated cell lines ( Figure 3 ), albeit statistically non-significant when compared to other cell lines.

In contrast, both L1s and Alu repeats had a frequency-dependent effect with highly significant correlation ( Figure 3 A–F).

* p < 0.05 was considered significant, ** p < 0.01 and *** p < 0.001 were all considered extremely significant.