Excerpts

In contrast, patients with a bladder volume higher than the median showed a trend towards a decrease in the progression of urinary symptoms with a median recovery time of 12 months.

Currently, CCA represents around 15% of all primary liver cancers, with an increasing trend during the last decades due to better awareness of the disease and diagnostic advances, accounting for 3% of all gastrointestinal neoplasms [ 1 , 2 , 3 ].

Subsequent further studies on iron metabolism found that, unlike RSL3, the content of intracellular LIP showed a decreasing trend, but mitochondrial iron overload could be achieved through the mitochondrial membrane Ca 2+ /Fe 2+ transporter (MCU).

Additionally, an assessment of tumor grade in neoplasia revealed an interesting trend [ 42 ].

It was observed that there is a decreasing trend in microbiota richness as the tumor grade increases.

Concretely, when CKD stages increase, prognostic grade groups show a decreasing trend, and conversely, when prognostic grade groups increase, CKD stages decrease.

[ 54 ] indicated an increasing trend for Streptococcus and Neisseria .

However, a recent study showed an increasing trend in the incidence of UTUC in Taiwan that may be attributed to the consumption of unknown sources of AA.

p values < 0.05 and <0.01 were considered significant and highly significant, respectively.

An overall trend of higher percentage of patients with copy number gain, compared with copy number loss (annotated as “gain%” and “loss%”, respectively, in Supplementary Tables S2 and S3 ) was observed.

The incidence and mortality of colorectal cancer in China have shown an increasing trend.

The existing literature on this subject matter now provides compelling evidence pointing towards a statistical trend in favour of extended OS and PFS in cases involving craniotomy with resection, as opposed to the purely diagnostic stereotactic biopsy procedure.

The fourth important feature was the gray-level co-occurrence matrix Informational Measure of Correlation (glcm_Imc1 96 × 96), and it had a negative trend: a higher feature value resulted in a lower negative SHAP value.

In the last two decades, the availability of the robotic platform has created an increasing trend toward the minimally invasive surgical resection of HCC as large as hemihepatectomies [ 71 , 72 , 73 , 74 ].

In particular, our (near-significant) results regarding the analysis of adjuvant systemic treatment, as well as those of the separate analysis of subcohorts with different counts of treated metastases, could both benefit from larger sample sizes, in order to clearly define the potential influence of these factors on PFS and OS.

The distribution of cancer types shows an increasing trend over the last few years.

A significant trend observed in the literature was the application of machine-learning and deep-learning techniques for the diagnosis and prognosis of CC.

These tumors are largely resistant to calcitriol with only a slight trend towards smaller growth visible.

All three BCAAs showed a trend to be elevated in tumour liver samples.

Apart from a slight trend towards higher serum concentrations of S100, which was statistically not significant, there was no indication for a correlation between the tumor marker concentration and the PET/CT results.

Among the variables analyzed, the type of anticancer drug used, categorized as C, CI, I, or M, emerged as a highly significant factor affecting 5-year OS.

LMWH showed a trend towards lower mortality rate (risk ratio (RR) 0.66; 95% CI, 0.40–1.10) and lower recurrent VTE (RR 0.69; 95% CI, 0.27–1.76) compared to UFH.

ICI type showed a marginal significance (0 = 0.0569) based on univariate model ( Supplementary Table S2 ).

An increasing trend in the incidence of HL has been observed, influenced by factors such as female sex, younger age groups, and Asian countries [ 3 ].

Comparing the values of the age groups, there was a nearly significant difference only in the RDI > 85% cohort.