Barely Significant

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Secondary research questions Energy content of highest ranked option Hypothesis 2: In Study 1, if the highest-ranked option was lower-energy, it was less likely – with an odds ratio of 0.80 (95%CIs: 0.67, 0.95; p = 0.013) – that the selected option matched that highest-ranked option, although this did not reach statistical significance at the pre-specified value of p < 0.003.
highly significantp = 0.0050.1× alphaqualifiedgold
[ 39 ] reported markedly higher risks for females, with ERR/Gy of 4.22 (90% CI 1.72 to 7.21) for all CVD, 6.17 (90% CI 2.44 to 10.92) for ischemic heart disease (IHD), and 2.67 (90% CI < 0 to 9.79) for CeVD, compared with ERR/Gy for males for the same endpoints of 0.20 (90% CI 0.07 to 0.36), 0.16 (90% CI -0.01 to 0.34), and 0.48 (90% CI 0.10 to 0.91), respectively; these differences were highly significant for all CVD ( p = 0.005) and IHD ( p = 0.004), but not for CeVD ( p > 0.50) (Tables 2 and 3 ).
highly significantp=0.0060.1× alphaqualifiedgold
Greater willingness to evacuate from home showed a highly significant relationship with high income (>$80,000) compared to very low income (<$20,000) (AOR=3.01, p=0.006); and was also positively associated with female gender (AOR=2.01, p=0.012), and high self-rated personal resilience (AOR=1.87, p=0.010).
a significant trendp = 0.00670.1× alphagold
Similarly, when examining the yearly occurrence of OPSCC in males, we found a significant trend for both p16 positive cases (Spearman r = 0.9286, p = 0.0067; linear regression R 2 = 0.8675, p = 0.0023) and p16 negative cases (Spearman r = 0.8469, p = 0.0238; linear regression R 2 = 0.7591, p = 0.01) (Fig. 1 C).
a positive trendP = 0.0094100.2× alphagold
Trends of other causes according to ethnic/racial background have also shown a similar trajectory to alcohol-induced trends, as from 1999 to 2008, the Black/African American population have shown a marked descend (APC − 2.9179%/year, 95% CI: -3.3539 to -2.4800, P < 0.000001), and from 2008 to 2014, kept decreasing (APC − 0.3465%/year, 95% CI: -1.4012 to +0.7194, P = 0.487667), with even a further descend from 2014 until 2018 (APC − 2.1343%/year, 95% CI: -4.3455 to +0.1281, P = 0.061945); however in 2018, a major shift occurred with a positive trend up until 2021 (APC +6.3883%/year, 95% CI: +1.8690 to +11.1081, P = 0.009410), followed by a major descend from 2021 to 2023 (APC − 4.2571%/year, 95% CI: -8.2248 to -0.1179, P = 0.044907) (Fig. 4 C).