Unexpectedly, we found a tendency between lower CAT scores and a high number of previous severe COPD-related exacerbation and the presence of obesity (trend toward significance).
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Though it does trend toward significance for all participants, none of the analyses meet our pre-specified definition of meaningful effect size or statistical significance.
In addition, CIS female rats have significantly more Akt1 expression compared to CIS males (P = .018) in the medial hippocampus and trend toward significance in the lateral hippocampus.
Discussion In the present study, we demonstrated that the obesity measures BMI, fat mass, hip circumference, and waist circumference are correlated with PA as well as with three FTO variants, and that there was some trend toward significance in the interaction effects between PA and FTO genetic variants on these four obesity-related phenotypes in a Latino population.
Similarly, for the recommendation of any CAM treatments from a doctor in the last 12 months, the odds ratio was higher for individuals with tertiary education (OR 2.39; 95% CI: 1.00–5.67, p -value = 0.05), suggesting a potential trend toward significance, indicating that higher education may be associated with a greater likelihood of receiving CAM treatments.
We found increased BMI to trend toward positive postoperative sagittal alignment, and although our regression model did not determine increased BMI as having a significantly lower association with negative sagittal balance postoperatively, it did trend toward significance.
However, although not statistically significant, both SMI-L3 and its derived sarcopenia-related cut-off demonstrated an overlapping trend toward significance in line with the other individual aforementioned predictors (aOR: 0.96, 95% CI: 0.92–1.1 and aOR: 2.33, 95% CI: 0.99–5.52) ( Table S1A ).
Figure 4 demonstrates the ultimate models of MCI participants, wherein some mediators exhibited a minimum of the trend toward significance in the mediation pathway.
In linear regression, while P < 0.05 was considered to be statistically significant, in the results interpretation a P -value of 0.05–0.10 was considered to suggest a potential trend toward significance.
Significant direct associations for biological variables were observed for SBP ( r = 0.199), pulse pressure ( r = 0.239), blood pressure risk ( r = 0.269), trend toward significance were present for Friedewald fraction ( r = 0.143) and serum triglycerides ( r = 0.143).
Though there were no differences in language skills that were statistically significant, the trend toward significance in the MLU indicates that maltreated children may produce shorter utterances in their spontaneous speech.
Multivariate analysis did not show T-stage as an independent predictor of OS, though it did trend toward significance.
Many variables have shown a promising trend toward significance in forecasting CT scan improvement: younger age, female sex, fewer overall burden of smoking, absence of hypertension, higher lymphocyte count at admission, lower N-terminal pro-brain natriuretic peptide (nt-proBNP) at admission, therapy with lopinavir/ritonavir.
This may have led to the non-significant statistical comparison between EM and AC group training times despite the trend toward significance.
Variables with a p-value of less than 0.1 were considered “potential predictors” due to their trend toward significance and clinical relevance, even though they did not meet the conventional statistical significance of P < 0.05.
Sensitivity analyses defining hypogonadism as TT < 300 and <250 ng/dl showed similar point estimates and trend toward significance (OR 300 : 0.21, 95% CI: 0.05–0.81 and 0.19, 95% CI 0.03–1.43; OR 250 : 0.19, 95% CI: 0.05–0.69 and 0.16, 95% CI: 0.02–1.2, for 4000–8000 and 8000–12,000 CPD, respectively) (Fig. 2 ).
Moreover, the NaF combination remained effective compared to the placebo at 10 minutes (6.00 ± 1.20 vs 6.20 ± 1.40, with trend toward significance) [65] ( Appendix S12 ).
Deformation Analysis Regional strain: At 1 year follow up, an improvement in peak circumferential systolic strain values was noted in all LV myocardial segments; this improvement showed statistical significance in 15 segments and trend toward significance in the remaining two segments.
While time from ORIF to THA did not reach statistical significance in our cohort, it did trend toward significance.
The is also suggested by the trend toward significance with fetal vascular malperfusion.
Given our modest sample size, and the trend toward significance when using a categorical indicator for delirium, our results suggest a potential association between delirium and change in disability.
When examining TKAs (n = 128) separately as a group, there was also no difference in inpatient MMEs (114.9 vs 105.9, P = .36) or outpatient prescribed MMEs (191 vs 158, P = .06) between the self-reported cannabis users and matched controls, respectively, although the outpatient prescribed MMEs did trend toward significance.
Two-tailed P< 0.05 was considered significant, and P ≥0.05 but <0.1 was defined as “trend toward significance”.
Subjects with high plasma LDL-CH were also characterized by higher FGF21 and lower adiponectin (presenting trend toward significance) serum levels (Table 1 ).
It is therefore possible that the trend toward significance with respect to the analyses of response control underestimated the real effect; hence, there may be a risk for a type II error.