Observation of proliferation and cytokine secretion patterns showed a trend towards reduced proliferation by the risk haplotype when compared to the protective haplotype.
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In the literature
A high EGFR copy number showed a trend toward poor prognosis in the absence of EGFR-TKI treatment [ 10 , 11 ].
Critical mid-G 1 factors, CDK4 and CDK6 showed a trend toward upregulation by TRIM16 knockdown.
Treated hAPP mice also showed a trend toward lower numbers of γH2A.X-positive foci in the entorhinal cortex ( Fig. 6c ).
In stage-matched analysis for OS and RFS, MBC showed a trend toward better survival compared to IDC-NOS, especially in the TNM stage II cohort, but this trend was not statistically significant (Figure 2 A,B).
The main effect of group ( F 1 = 3.14, P = 0.08) did not reach significance, but the interaction groups × electrode ( F 3 = 2.588, P = 0.06) showed a trend.
Although genotype CC showed a trend toward a protective effect in infants of European descent, the result is not significant (Figure 2 Forest plot).
While motility (a measure that encompasses both extension and retraction) did not translate into increased length over 8 h of imaging, axons showed a trend in this direction.
Additionally the jail technique showed a trend for better outcomes in terms yield load, stiffness and displacement though the differences did not reach statistical significance.
While the dose of 1ppm Se-enriched milk protein used in the present study was several fold greater than that used for human intervention studies (200 μg Se/day) [5] , our previous studies indicated that 1ppm Se was at the lowest range of Se forms to be effective in the AOM model, Se-enriched milk protein at 0.5ppm also showed a trend towards protection [28] .
Also, as strain 48 showed a trend of increasing excretion, it suggests that this strain is a robust colonizer of mouse intestine.
Vicarious activation in SI showed a trend for a positive correlation with the personality trait openness to experience.
Progressively loaded group showed a trend for higher bone density gain compared to the conventionally loaded group, but when tested with repeated measure ANOVA, the differences were not statistically significant ( P > 0.05).
In contrast, manual acupuncture produced no significant change in the TS threshold, although it showed a trend of increase as compared with sham acupuncture.
While in WI or CS group they appear inhibited or reduced, we showed a trend towards increased for TGFβ and a significant rise of its first downstream mediator pSmad3 in WI + CS, indicate a maintain production of collagen and a progression of renal fibrosis accentuated by MMP-2 decrease expression supporting a less extracellular matrix degradation.
Although no significant differences were recorded, participants reporting a dry mouth sensation showed a trend of attaining higher prevalence of impact on the “physical pain” dimension (53%).
A recent study to determine the survival rate after infection in glioblastoma multiforme patients demonstrated no survival advantage in patients with post-operative infection but they did find that the deep infection subgroup showed a trend towards increased survival [ 61 ].
In accordance with the elevated histone H3 levels in the RTT samples, the modified versions of histone H3 investigated—histone H3 trimethylated on lysine 4 (H3K4me3), histone H3 acetylated on lysine 9 (H3K9ac) and histone H3 acetylated on lysine 27 (H3K27ac)—showed a trend toward higher levels of occupancy in the RTT samples with the only statistically significant change being an increase in H3K9ac on the myoglobin exon (data not shown).
Interestingly, the inverse correlation observed for bCSp did not reach statistical significance (2A) when epitope-conservation was defined as mCSp (r = −0.40, p = 0.139, Figure 6A ), although the data showed a trend in the same direction as was observed for the bCSp analysis.
Concerning BRCA1, the positive patients showed a trend of better outcome than the negative ones.
However, the proportion of the type 1 fiber showed a trend for being higher, because the ratio of type 1 to 2 myofibers was 1 to 2.
The operation time tended to be shorter, an earlier discharge from hospital was possible and the treatment showed a trend to be completed faster.
Three findings from our data support this hypothesis: 1) DRB1*15 is associated with OCB+; 2) the combination of non-HLA markers associated with MS susceptibility also showed a trend for association with the presence of OCB as suggested by our wGRS, although most of its predictive power comes from DRB1*15; 3) after meta-analysis of the Italian best associated markers with two independent data-sets, we found a non-HLA SNP on chromosome 6 that almost reached GWAS significance.
Treatment with D-ribose resulted in no significant change in body weight but showed a trend towards a decrease in weights.
Three mutants: R154K, T110N, and L6I, also showed a trend of reduced fitness, although not significantly different from the prototype (95% CI p>0.05).