It was conspicuous that the R3327 cells and its metastatic subline MAT Ly/Lu showed a trend towards formation of spherical structures ( L) , whereas the DU-145 grew as a monolayer ( C) .
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While not a primary outcome of this study, this subgroup analysis showed a trend between higher adherence and larger decreases in HbA1c values.
Patients categorised as ‘positive’ showed a trend for greater adherence (as measured by self-reported number of times using the programme) and more often reported completing the programmes.
Magnani et al 17 showed in a retrospective study that patients with JIA who attained an ID state at least once in the first 5 years of their disease less frequently experienced long-term joint damage, and they also showed a trend towards less functional impairment and radiographic changes.
Nevertheless, these data have showed a trend towards improved survival, mostly achieved by the application of multimodality treatment, which consists of surgery, WBRT, or SRS administration with concomitant or sequential TKI therapy.
Adding dexamethasone at later time points (day 3 or day 7) showed a trend for lower YKL-40 expression and secretion (Fig. 4a and b , middle and right panel, respectively), but failed to reach significance.
In contrast, PEG-PAsp(TET) nanomicelle-injected group showed a trend of sustained luciferase expression for up to 4 days ( Fig. 1a,b ).
Although statistically insignificant, the finding showed a trend wherein negative Wnt5a was associated with large tumor size.
Most of the drug effects of varenicline on smoking measures were seen by week 2 or week 4 of study drug treatment, and the magnitude of the difference between varenicline and placebo groups showed a trend for increase on some measures in subsequent weeks.
48 found that MCI patients showed a trend toward reduced hippocampus activity compared to healthy elderly.
The wild-type 7D8 showed a trend of activity, but did not reach statistical significance compared to controls.
The larger, accredited teams showed a trend for lower non-relapse mortality but higher relapse incidence; they might have a shorter waiting time, associated with a slightly higher risk profile of their patients ( Frassoni et al. 2000 ).
In isolated human islets, RO5166017 also showed a trend to increasing glucose-dependent insulin secretion, although this effect was not significant ( Figure 1 F). 3.2 TAAR1 agonist improved glucose tolerance During an oral glucose tolerance test (oGTT) in C57BL/6 mice, a single dose of RO5166017 (0.3 mg/kg, p.o.) significantly reduced glucose area under the curve (AUC 0–120 ) by 20% ( Figure 2 A) with no effect on fasting glucose.
When calculated per larva, there was no statistically significant change in TAG levels on the different diets, although the carbohydrate- and lipid-rich diets showed a trend towards increased TAGs ( Fig 1A ).
It showed a trend toward poor outcomes for both DFS and OS, but these were not statistically significant.
Thus, the bio-concentration factor (BCF) values of metals in the food crops showed a trend in the order of Cr > Zn > Ni > Cd > Mn > Pb > Cu ≈ Fe.
In this regard, a subanalysis of the TRIBE study recently showed a trend for increased survival with FOLFOXIRI compared to FOLFIRI (irinotecan with fluorouracil and folinic acid) in BRAF-positive patients, this difference was not statistically significant possibly due to the low prevalence of BRAF-positive CRC. 54 Ongoing studies are evaluating BRAF inhibitors in combin
The prevalence of the 4 CSP types showed a trend toward a reduction from the 1st to the 18th hospitalization.
Patients in the CG showed a trend to be more satisfied.
However, its 35-kDa fragments showed a trend toward accelerated clearance in the presence of CUL2, which was significant at 5 h after CHX treatment in WT TDP-43 ( Fig. 4d ).
The expression levels of Bax after HEMA or MMA treatment also showed a trend of increase, although there was no statistical significance compared to the control group (all P > 0.05).
The frequency of motile events showed a trend to decrease but was not statistically significant in the SMN-FL knockdown neurons ( Fig.
The Afmid tm1b/tm1b islets showed a trend of secreting less insulin in response to 500 μM tolbutamide plus 20 mM glucose compared to Afmid +/+ islets ( Fig. 5 B).
Titration of the total viral RNA copy number and the transduced proviral copy number showed a trend towards reduced vector titre as the length of packaged sequence increased.
In conclusion, CC non-responders showed significantly lower (E)-clomiphene concentration than responders, and also showed a trend of decreased concentrations of active metabolites.