This also showed a trend in favor of the capecitabine-containing arms in terms of response rate and progression-free survival as follows.
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In the literature
Although there are no data available concerning the relationships between B-vitamins fortification of a variety of foods and the global increasing prevalence of obesity and type 2 diabetes, the notable facts are that: (1) compared with formula-feeding, breastfeeding is associated with a reduction in risk of later overweight and obesity [ 45 - 47 ]; (2) high consumption of processed meat is a strong risk factor for type 2 diabetes [ 48 ]; and (3) the global prevalence of obesity and type 2 diabetes showed a trend of spreading from the earliest fortified-countries to the latter fortified-countries, whereas the non-vitamin-fortified countries including western developed countries, such as Norway, have a low prevalence of obesity and diabetes, compared with the earliest fortified-countries, such as the US and Canada [ 49 , 50 ].
highest adiponectin quartile, this difference showed a trend towards statistical significance (p for trend = 0.09; Table 3 , model 1).
Although the study was limited by the follow-up time, the early results were promising and the long-term outlook depicted in the Kaplan-Meier curve showed a trend towards long-term survival [ 16 ].
Estimation of outcomes using the Kaplan–Meier method showed a trend towards a better outcome in the group with lower expression level of the BMI1 gene.
Kozar et al 28 suggest that a brief intervention can help influence students toward general surgery; although their data only showed a trend towards an increase in general surgery choice and no change in surgical specialty choice.
The dry weight per individual (μg) of all macrobenthic nematodes combined showed an increasing trend with increasing water depth, while the dry weight per individual of the meiobenthic GOM nematodes showed a trend to decrease with increasing depth.
Several retrospective, prospective and meta-analysis studies failed to indicate that PPPD causes an increase in hospital stay.[ 8 , 12 , 14 , 15 ] In fact, one meta-analysis and one retrospective study showed a trend toward a shorter hospital stay with PPPD[ 9 , 11 ] TUMOR RECURRENCE AND LONG-TERM SURVIVAL The adequacy of PPPD as a cancer operation has always been questionable especially after Sharp and his colleagues had reported three cases of PPPD where the duodenal resection margin was positive for carcinoma.[ 32 ] That observation, however, was not supported by other studies.
cholerae O139, which emerged during 1992 and 1993, was sensitive to tetracycline and showed a trend of increased resistance to trimethoprim-sulfamethoxazole (SXT) and streptomycin.
A fifth SNP (rs9297756) was associated with an increased risk in DALS (OR = 1.22; 95% CI: 1.07-1.39) but showed a trend toward decreased risk in the WHI (OR = 0.93; 95% CI: 0.74-1.18).
The PAC1-deficient mice also showed a trend of increased plasma gastrin levels and gastrin gene expression in the gastric mucosa.
Behavioral changes after elation are not systematic across participants as some of them showed no systematic deviation of the circular uniform distribution after elation while others showed a trend to increase (or decrease) expectations.
Pre-cART CD4 count <50 cells/μl, HIV RNA >5 log 10 copies/ml and BMI <18.5 were independently associated with OI-IRIS, but only the BMI showed a trend for predicting MC-IRIS ( Table 4 ).
The Atrial Fibrillation Follow-up Investigation of Rhythm Management study, which compared the rate vs rhythm control in participants with atrial fibrillation older than 65 years, showed a trend toward higher mortality in the rhythm control arm.
Male mice were used because they showed a trend to higher arthritis severity compared with female mice.
The βDKO mice showed a trend toward higher insulin secretion compared with β Ric KO animals, but these differences were not significant.
SFC showed a trend towards improvement in FEV 1 compared to concurrent therapy with separate inhalers but it was not statistically significant ( P = 0.54; 95% CI, 0.00 to 0.08).
The KRAS13 mutation showed a trend towards poor OS in patients with advanced and recurrent CRC.
Depletion of cytolytic CD16 + NK cells, although short-lived and incomplete, showed a trend towards higher levels of SIV replication in NK cell-depleted monkeys compared to control monkeys [29] .
This study demonstrated that the IAC mean doses > 50 Gy showed a trend to increase the incidence of high frequency (4 kHz) SNHL (RR 2.02 with 95% CI 0.99-4.13).
Women without any children showed a trend of having more overweight.
The D/EPI arm showed a trend towards a superior improvement in a number of quality of life dimensions compared with the D/P arm, particularly pain and physical function subscales, and global quality of life.
In addition, the double mutant showed a trend towards decreased gene expression of the ABA-biosynthetic gene NCED3 ( Fig. 6 ).
Results Of the 12 SNPs, eight showed a trend with increased risk of type 2 diabetes, consistent with their BMI-increasing effects.
The studies also showed a trend over the recent decades towards an increase in the prevalence of dyslipidemia in China, parallel to a change in the lifestyle.