Using the log-rank test to determine the significance of lymphocyte infiltration for survival, only stromal ( P =0.0534) and intraepithelial ( P =0.0402) CD3-positive T cells showed a trend and significant correlation with DFS for stage III patients with optimal debulking, respectively.
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This difference showed a trend but was not statistically significant ( P =0.08).
In addition, infarcted hearts of TSP-1- null mice showed a trend towards decreased phosphorylation of the intracellular effector of TGF-β 1 , Smad2.
5E ; Tukey's, p<0.01) and also showed a trend towards a decrease in AE vs.
This effect was dose dependent because administration with 250 ng/ml of chemerin showed a trend toward induction of insulin resistance, whereas 1 μg/ml of chemerin provoked a significant decrease in insulin-stimulated phosphorylation of Akt and GSK3α/β.
Some groups showed a trend in opposite direction: Turkish women of second generation smoked significantly more than ethnic Dutch women, while the first generation did not differ from ethnic Dutch.
The evaluation of individual studies showed a trend towards a direct association between salt intake and risk of cardiovascular disease in 10 cohorts, with significantly higher relative risk in six.
Immunoblotting with a pan-PDE4A antibody showed a trend in sleep-deprived hippocampal tissue towards an increase in a 125 kDa species, which is of a size expected for the long PDE4A5, PDE4A10 and PDE4A11 isoforms 23 ( Supplemental Fig.
43 The combined analysis from both trials performed by the Cochrane Group showed a trend towards for beneficial effect favoring the treated group. 45 A third placebo-controlled trial has been recently completed. 44 There was no difference between treatment groups in the primary and secondary outcome measures after a two-year follow-up period. 44 In conclusion, r-IGF-I is well tolerated but, although so far is the only agent other than riluzole to show on any ALS markers of disease progression, can not be considered beneficial for patients with ALS.
However, even these tissues showed a trend towards increased expression of the Chodl-002 isoform in SMA compared to control mice ( Figure 5C ).
However, the TNFα-induced GAG release was significantly reduced by TIMP-3 by approximately 52% (Figure 1c ), whereas TIMP-1 and TIMP-2 showed a trend to increase the TNFα-induced GAG release, although this effect was not significant.
Although exemestane showed a trend to inhibit aromatase activity 15 min after its application in both cell cultures, this inhibitory effect was reversed 6 h later.
When the mean annoyance scores were compared, age groups showed a trend with older people less annoyed than the younger ones with the exception for the 18–24 group.
However, in the K-RAS mutant group, RR showed a trend toward a worse rate in the cetuximab plus FOLFOX4 arm (33%) vs.
As slower islets showed a trend, albeit non-significant, to have slower single cells than faster islets, it is possible that the oscillation periods of single cells do reflect imprinting, but that this is obscured by the vastly increased heterogeneity of the single cells apparent in Fig. 4 and anticipated from theoretical modeling [53] .
Although both showed a trend for improvement in walk time, P-value did not reach statistical significance in one study [ 19 ] and was not reported in the other [ 16 ].
From P2, rMSCs became morphologically homogenous, had a fibroblast-like phenotype, and showed a trend to become smaller with increasing passages (from P16 to forward passages).
Notably, two ROIs [( x , y ) = (40, −45), (50, −45)] close to the right fusiform region (40, −44, −18) identified in the localizer scans showed a trend of training effects for the individuation-training group that did not reach significance ( P s>.40).
Due to the functional importance of AQP1 and SLC4A10 in CSF production, sequence variants within these two genes might be expected to be more prevalent in NTG patients since both a retrospective and a prospective study showed a trend of NTG patients having lower CSF pressure than POAG subjects [ 12 , 41 ].
The L* axis also showed a trend towards lighter hair colour associated with the A genotype, although this is not statistically significant (Figure 3 ).
In our study, differences in renal size between male SGA, AGA, and control individuals seemed smaller than those between female study participants but still showed a trend for decreased absolute renal length and volume.
S47A mutants showed a trend toward increased basal and ligand dependent activation in reporter assays, but did not reach statistical significance.
magna , the two maize varieties were not performing similarly: (1) the survival of the GM-fed animals were significantly lower than UM-fed, without predator ( p = 0.037, coxph -test), but not significantly different for the group with predator or for the total material ( p = 0.45 and p = 0.16, respectively, coxph- test); (2) the total number of eggs produced by GM-fed animals were lower as compared to animals fed on UM-maize; (3) the growth showed a trend towards larger body sizes in the UM-fed group without predator smell present (Bøhn et al. 2008 ).
In the anterior and synovial tissue the number of ERα positive cells in the No E 2 /saline group trended (showed a trend to be) higher than in the No E 2 /CFA group, suggesting the CFA induced a decrease in ERα levels, consistent with the western results.
Nutritional differences demonstrated during the intent-to-treat analysis disappeared when examined on a per-protocol basis although gastric feeding still showed a trend toward higher average nutritional intake.