Similarly, a significant increase in protein expression was observed for MYB and IRF8, whereas SPI1 showed a trend that did not reach statistical significance ( Fig. 5, b and c ).
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The p-β-ionone showed a trend similar to that of the p-β-cyclocitral, whereas the d-MIB concentration was higher in the spring and autumn than in the summer and winter.
Surprisingly, natalizumab induced a modest reduction of MMP-2 secretion, as did CD3/28 costimulation in a synergistic manner (p<0.05), and it showed a trend towards a reduction of MMP-9 protein secretion, which in contrast to MMP-2 was strongly induced by CD3/28.
Although, asexual populations showed a trend for higher evolvability in the red noise environments, effects on both viability robustness and evolvability were not statistically significant.
31P MRS, MRI and Maximal Aerobic Capacity Test SRT2104 0.5 g/day and 2.0 g/day showed a trend for a decrease in half-time for recovery of the calculated adenosine diphosphate (ADP) concentration (ADP T 1/2 ) values after exercise, on day 27 relative to baseline ( Table S1 ).
The agonistic bis-Fabs showed a trend toward being more compact molecules, as judged by their hydrodynamic radii ( Table 1 ).
Higher N stage (N2 and N3) showed a trend of poor PFS.
Overall, the global gene expression profile showed a trend where HvLg and HvHg pigs had lower expression of the listed genes relative to LvLg and LvHg pigs, respectively, indicating that the defense mechanism mediated by cell death had reduced efficiency, thereby allowing increased viral replication.
showed a trend to association with breast cancer risk in BRCA1 carriers aged <50 years [26] .
Cluster D genes that showed a trend for upregulation already by 12 hours and mostly stayed upregulated throughout the culture were enriched for genes involved in kinase activity and DNA repair ( Figure 5D–E ).
While at t 1 , diatom growth rates showed a trend to increase with temperature, at t 2 , all groups showed tendentially highest growth rates at 18 °C (Fig. 3 ).
Data for the uncinate also showed a trend for greater force requirement in live patients but the difference was not statistically significant.
In the subgroup meta-analysis by the number of participants in each trial, vitamin or antioxidant supplements showed a trend toward a decreased (but not significant) risk of major cardiovascular events (relative risk 0.97, 95% confidence interval 0.94 to 1.01; I 2 =40%) in the subgroup meta-analysis of trials with <10 000 participants, while those supplements showed an increased (but not significant) risk of the major cardiovascular events (1.02, 0.99 to 1.04; I 2 =39%) in the subgroup meta-analysis of those with ≥10 000 participants (table 4).
Surprisingly, however, musicians showed a trend toward over-estimation of the temporal interval in both the between -group and within -group conditions.
The data showed a trend towards diminished SSAO activity in the lysates of VAP-1Δ3-co-transfected cells when compared to the control transfected cells, even though the results did not reach statistical significance ( Figure 5C ).
Indeed insertions in this exact location have been shown to activate Jdp2 expression, 34 and consistent with this, qPCR on RNA from tumours containing insertions in Jdp2 showed a trend towards having higher expression levels of Jdp2 and lower expression levels of Trp53 , relative to Trp53 +/− tumours with no insertions in Jdp2 (randomly selected from mice on this study that had not lost the Trp53 allele by mitotic recombination; Figure 3d ).
The estimated cumulative HIV-1 incidence curves in the vaccine and placebo groups illustrate VE for two genotypes (K169 and I181X) and no efficacy for the opposite residues ( Supplementary Figure S2 ) (diagnostic tests did not show significant evidence of violation of the proportional hazards assumption) – and the cumulative HIV-1 incidence curves showed a trend toward waning vaccine effect on genotype over time, analogous to the temporal effect on efficacy seen in RV144 1 , 12 .
Levels of Aβ 42 measured using conventional immunoassays showed a trend in the opposite direction as has been well described, including in the current population [ 15 , 20 ].
Patients with baseline ferritin levels <100 ng/ml showed a trend to achieve a median Hb ≥11 g/dl earlier (week 4) than those with baseline ferritin ≥100 ng/ml, who achieved Hb ≥11 g/dl by week 6 (Figure 1 C).
Most of these genes were lowly expressed in both benign and malignant meningiomas ( Table S1 ); however, five genes ( ADCY3 , GAS7 , LAG3 , LRR32 and SPON2 ) showed a trend of elevated expression (>3 fold in mean values) in malignant meningiomas.
1F ) showed a trend to be lower in CR WT mice, and this trend reached statistical significance in TgTERT mice after 12 months of CR diet compared to the corresponding cohorts under a control diet ( Fig. 1F ; p = 0.006 ) .
Patients with negative nuclear ADA3 staining or positive cytoplasmic ADA3 staining in tumors showed a trend toward shorter DMFS; however, the association was not statistically significant ( p = 0.063 and p = 0.050, respectively) (data not shown).
Three schizophrenia and one epilepsy study used MEMS, and all showed a trend towards higher adherence rates with less frequent dosing regimens.
Although not significant, fish trained at constant-velocity showed a trend towards higher survival than fish trained at either short or long intervals.
These patients also showed a trend for shorter PSA-free survival (Figure 3 ).