“showed a trend”

Cardiac function Left ventricular ejection fraction (LVEF) did not differ significantly among T2DM, T1DM, and control groups ( P = 0.153), although PwT2D showed a trend toward lower LVEF.

Stage-specific growth patterns showed a trend of decreasing VDT with disease progression.

3.2.3 Subgroup analysis for overall survival by PD-L1 expression 3.2.3.1 PD-L1 <1% For SQ-NSCLC (data from 7 trials involving 1, 047 patients and 7 ICI combination regimens), nivolumab plus ipilimumab was associated with prolonged OS compared with atezolizumab plus chemotherapy (HR = 0.56, 95% CrI: 0.32–0.98) and showed a trend toward improved OS compared with pembrolizumab plus chemotherapy (HR = 0.59, 95% CrI: 0.33–1.05); it was ranked as the most effective regimen (SUCRA = 0.83).

In the KEYNOTE-789 study, in the PD-L1-positive subgroup, the Pembrolizumab plus chemotherapy group showed a trend toward improved OS ( 23 ).

The pooled analysis showed a trend toward a shorter length of hospital stay in the bosentan-related treatment group than in the control group, but the difference was not statistically significant (MD = −1.06, 95% CI: −2.38 to 0.27, P = 0.12).

Disproportionate LV remodelling was correlated with increased phosphorylation and showed a trend towards increased N2BA titin, both markers of decreased myocardial stiffness.

Procedural learning performance was positively correlated with cerebellar cortical volume, and children with DCD showed a trend toward reduced cerebellar volume compared to TDC ( Bianco et al., 2024 ).

A single intravenous injection of this LNP formulation showed a trend toward dose-dependent reduction of HBV antigens.

In the multivariate Cox analysis of the training cohort, the high-risk group showed a trend toward increased risk (HR = 2.454, 95% CI: 0.817–7.371), although the association did not reach statistical significance (P = 0.110).

The results showed a trend towards clinical improvement and significant reductions in inflammatory markers. 362 Another drug that targets the B-cell signaling pathway by acting on the BTK inhibition is Evobrutinib, which is being primarily investigated for autoimmune diseases like MS, Rheumatoid arthritis, and SLE.

Meconium-stained amniotic fluid showed a trend toward association but did not reach statistical significance (p = 0.082).

31 – 34 In the present study, patients receiving radiotherapy showed a trend toward prolonged PFS and OS compared with those who did not receive radiotherapy.

After adsorption, the Pb 2+ content and protein content in LB-EPS and TB-EPS showed a trend of first increasing and then decreasing, which was due to the gradual diffusion of Pb 2+ in S-EPS to LB-EPS and TB-EPS.

Our exploratory meta-analyses generally mirrored the qualitative synthesis: exercise interventions showed a trend toward improvements in QOL but no impact on psychological distress, consistent with previous reviews, which found benefits for QOL but no effects on distress. 197 , 198 The broader literature suggests that exercise may confer benefits through reductions in fatigue and sleep disturbance as well as i

Similarly, the group with a higher proportion of p16-positive CAFs showed a trend toward worse prognosis compared with the group with fewer p16-positive CAFs ( Figure 1 K ).

In contrast, ω-3 fat, docosahexaenoic acid–derived HDHAs showed a trend of increase in the HD cortex but were not altered by cGAS deletion ( Fig. 7 F ).

To further evaluate the potential role of V-type ATPase, RNAi-mediated knockdown resulted in reduced gene expression and showed a trend toward decreased pathogen load and modest improvement in host survival.

Notably, patients with PR/CR to induction showed a trend toward improved OS irrespective of the de-intensification strategy ( Supplementary Figure S3 , available at https://doi.org/10.1016/j.esmoop.2026.107775 ).

Although exercise showed a trend toward improving pain, function, and ROM, statistical significance was not consistent, reflecting a modest but clinically meaningful effect.

Vitamin E supplementation in healthy male subjects showed a trend towards improving arterial compliance [ 111 ].

An analysis of the composite effect of the COVID-19 pandemic on EPI vaccination, specifically BCG and DTP/IPV/HIB 3, showed a trend, but non-significant delays for DTP/IPV/HIB 3 vaccination in the pre-COVID period compared to the post-COVID period (RR: 0.49 (95% CI 0.22, 1.05), p = 0.186) (Table 5 ).

Another large RCT, the Enquiring About Tolerance (EAT) study, examined introduction of six common potentially allergenic foods (cow’s milk, eggs, peanuts, wheat, whitefish, and sesame) from three months of age and showed a trend toward reduced peanut and egg allergy in infants fed considerable amounts of these foods [ 8 ].

Rifaximin co-treatment showed a trend towards a reduction of apoptotic cells, suggesting a protective effect against chemotherapy-induced epithelial cell death ( Figure 1J–K ).

The ratio distribution showed a trend similar to Alpha+Beta/Delta+Theta, being significantly lower in VS, MCS-, and MCS+ compared to CTRL.

Conversely, the oldest-old showed a trend toward higher readmission despite lower mortality, suggesting a phenotype of frailty, multimorbidity, and recurrent decompensation [ 46 , 49 ].