Barely Significant
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“showed a trend”

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In fact, HIV-1 controllers mounted significantly more responses to at least one of these three CE than did non-controllers (p = 0.0006; Figure 3C ) and showed a trend towards these being responses of higher functional avidity, even though only a fraction of the overall data points were included in this comparison (median 7,189 ng/ml, range 0.99–2.5×10 7 vs. median of 17,058 ng/ml, range 16.28–2.62×10 7 ; p = 0.0666, data not shown).
The fact that ChR2-evoked changes in blood flow showed a trend towards increased magnitude upon blockade of ionotropic glutamate receptors is suggestive of interneuron-mediated inhibition through tonic activation of presynaptic GABA-B receptors, as observed in the olfactory bulb [31] , [33] ; thus, the increased blood flow we observed could point to enhanced activation of metabotropic glutamate receptors through elevated presynaptic release of glutamate.
Reported sensitivity of D-dimer testing in the setting of suspected AoD is 100% and its degree of elevation even showed a trend toward extension of the dissection but not with the outcomes. 11 , 12 Even if it is not in the actual guidelines of AoD diagnostic algorithm, the use of D-dimer testing seems to be a good and reliable marker to rule out AoD in our differential diagnosis for patients presenting with acute chest pain.