“showed a trend”

17 – 20 Although recent studies showed a trend towards reduction of events including stroke ( Figure 1 ), 7 , 20 further improvement of therapy to reduce AF-associated events clearly is warranted.

The ratio of CD4+/CD8+ T cells showed a trend towards greater concentration of CD4+ T cell since day 1, despite the consistent and significant post-treatment increase in the distribution of NK cells expressing markers of CD8+ T cells.

Pulmonary histopathology showed a trend towards a decreased influx of inflammatory cells; however signs of severe pulmonary injury were not detectable in this early phase.

However, patients in the responder group showed a trend to inverse remodelling of the LV.

Retrospective data showed a trend toward improved cause-specific survival with higher radiotherapy doses.

This trial showed a trend towards better response with more prolonged treatment, with three of the four patients in the prolonged treatment arm B, maintaining their improvements for 1–3 years.

The mitochondria of irradiated hearts showed a trend to a smaller size but this did not reach significance.

Group II brains showed a trend towards astrocytosis, with some tufted cells.

Quantitative real-time polymerase chain reaction (qRT-PCR) analysis was conducted to determine whether or not there are interstrain or site-dependent differences in the gene expression profiles of skeletal muscles in SJL/J and A/J mice as dysferlinopathy models. Upon analysis by qRT-PCR, SJL/J mice showed a trend of increased gene expression level of uncoupling protein 2 in the rectus femoris and longissimus lumborum at 30 weeks of age when dystrophic lesions became histopathologically pronounced.

LOS The study showed a trend of shorter LOS in the LINFA group (median 3 (2–6) days) than in the placebo group (median 3 (2–7) days) but the difference was not statistically significant (p = 0.09).

Mesangial expansion, glomerular atrophy, and glomerular basement membrane thickening showed a trend to improvement in the sitagliptin-treated diabetic rats versus the untreated (Figures 3(b) , 3(c) , and 3(d) and Table 3 ).

Also the clipping treatment showed a trend towards elevation at intermediate treatment levels ( Fig. 4 ).

qRT-PCR data for GTPase RhoA ( Figure 3J ) and phosphatidylinositol 4-kinase ( Figure 3K ) showed a trend similar to that of the array data ( Figure 2A ), where GTPase RhoA showed fewer transcripts at the 4 or 12 h time points, and phosphatidylinositol 4-kinase showed lower mRNA expression at the 12 or 24 h time points in E 2 -treated samples compared to controls ( Figure 3J and 3K ). qRT-PCR also showed a significant increase in phosphatidylinositol 4-kinase transcript numbers at 24 hours of transition in controls compared to E 2 -treated samples ( Figure 3K ).

While the Powered bone marrow biopsy showed a trend toward decreased pain overall at the time of the procedures, use of the Powered bone marrow biopsy device did significantly decreased overall procedure pain when subjects considered the two procedures retrospectively.

In the presence of ACPA, these patients showed a trend toward lower erosion scores at all anatomical sites studied compared with ACPA-positive patients with the CC or CT genotype (C allele).

In contrast, ACP1*A allele (CG), which was the opposite allelic combination of ACP*C, showed a trend for protection against the development of CV events in RA patients, although no statistically significant association was achieved ( P -adj = 0.217, OR = 0.76).

Furthermore, patients with nasopharyngeal carcinoma showed a trend for higher risk for ischaemic stroke, whereas hypopharynx had a higher tendency for haemorrhagic stroke.

The measure of coronal skew was correlated with the AQ for prefrontal width (r = −0.19) and also showed a trend toward a low correlation with the cingulate sulcus trait, although this result did not meet standard thresholds for statistical significance after correcting for multiple tests. 3 Variance Component Analysis of Genetic and Environmental Influences Prior to estimating the genetic contributions to the AQs, we implemented variance component analysis to estimate the proportion of variance due to genetic (heritability estimate) and environmental influences on cerebral volume and width measurements from the left and right hemispheres (upper portion of Table 5 ).

Another 6 open-label or retrospective case studies showed a trend toward decreased sundowning and improved sleep quality. 90 Several recent studies which reflect use of melatonin specifically in patients with dementia, demonstrated that melatonin reduces sundowning behavior, nocturnal activity, decreases sleep latency, and improves quality of sleep. 89 - 91 De Jonghe et al. 47 performed a systematic search of the literature related to melatonin treatment in dementia which was published between 1985 and 2009.

While the plant showed a trend towards a geographically-driven structure of its genetic variation ( Figs. 1C and 1D ), insect haplotypes were distributed without regard to any spatial signal ( Figs. 2 and 3 ).

Conversely, the NO synthase inhibitor N-nitro-L-arginine methyl ester (L-NAME, 100 μM) showed a trend towards enhancement ( Fig. 4B ).

Subsequent analysis found that GMK had induced antibody responses in 80% of vaccinated patients, and that those patients who had developed anti-GM2 antibody response showed a trend to improve outcome compared to those without immune response—indicating that a lack of immune response was not to blame.

An interim analysis from the SAILOR (Safety Assessment of Intravitreal Lucentis for AMD) study showed a trend for an increase in the incidence of stroke in the group treated with 0.5 mg of ranibizumab [ 82 , 83 ].

However, while qRT-PCR analysis showed a trend towards increased Mist1 mRNA accumulation in response to LDC-HF or LDC-E diets, these differences were not significant ( Figure 6 ).

TX showed a trend toward increased pCR in patients with poor prognostic factors and hormone receptor-positive tumors [ 6 ].