“showed a trend”

( Figures 7J,K ) Soluble Guanylyl Cyclase Activator Improves Kinases Involved in Hypertrophic Pathways and Reduces Pro-Inflammatory Cytokines and Oxidative Stress in Human Heart Failure With Preserved Ejection Fraction Human HFpEF myocardium biopsies showed a trend similar to that observed in DSS rats, with a significant reduction of the sGC–cGMP–PKG pathway that could be attenuated upon treatment with sGC activator ( Figures 8A–C ).

Enzyme-linked immunosorbent assay (ELISA) for serum OCN further confirmed the remarkable positive effect of YB-EVs on osteogenic activity, whereas the AB-EVs-treated young and mice showed a trend of decrease in serum OCN compared with the solvent-treated control mice (Fig. 3l ).

Although hStrO neurons showed a trend toward increased excitability upon CGP treatment, this change did not reach statistical significance (fig.

Discussion The main findings of this study were that bilateral knee extensor neuromuscular fatigue decreased dominant EFs force production (large ES), lowered MEP/CMEP ratio (large ES) and showed a trend toward higher CMEP amplitude (medium ES) recorded from biceps brachii.

In comparison, 18 genes showed a trend towards upregulation ( Col4a3 , Fbln1 , and Vcan significantly so) on day 49 (n = 3, p > 0.05).

Transcript levels of CaSUT1 showed a trend of upregulation and then downregulation.

Furthermore, individuals belonging to the low BVR-A group showed a trend with increased VAT IL-6 mRNA expression levels with respect to the individuals in the high BVR-A group, while no significant changes or associations were found for TNF-α levels ( Figure 2 B).

Along gametogenesis, females showed a trend towards upregulation through oogenesis in Arriluze ( Figure 2 ), but no significant differences ( p > 0.05) were observed between mantles with ovaries in different gametogenic stages.

Following immunization with NP-CGG, quantification of serum Ab titers showed a trend towards lower total and high-affinity NP-specific IgM and IgG levels in CK2β KO as compared to CK2β CTRL mice, yet these differences did not reach statistical significance ( Figure 6G ).

Following a single SQ injection (acute dosing), an increase in dose from 3 mg/kg to 5 mg/kg resulted in a proportional increase in plasma concentrations and AUC, though this increase did not reach statistical significance and only showed a trend ( Figure 2 and Table 1 ).

Increasing age showed a trend toward higher risk of failure but did not reach statistical significance ( P = 0.052).

Nüzhenide showed a trend similar to that of nüzhenide 11-methyl oleoside for Frantoio and Leccino, while in Moraiolo, it slightly decreased from the first to the fifth sampling date, with a final sharp decrease at the two last sampling points ( Table 2 A–C).

ACTA2 as well as LMOD1 , previously connected to smooth muscle contraction, showed a trend to be upregulated after 24 h without stretch but only reached significance on rigid plates.

The Intra-Individual Variability Comparison in Muscle Synergy The intra-individual variability of W2 was significantly lower in older adults ( p = 0.032), and H3 in older adults showed a trend towards higher variability ( Figure 6 ). 3.4.

VOCs in region B showed a trend of increasing initially and then decreasing during boiling.

Further, individual skipping of exon 5 showed a trend of decreasing under OS, although this decrease was not statistically significant ( Fig 3B ).

Additionally, milrinone (MD [95% CrI] = 0.43 [−0.84, 1.7]) showed a trend of increasing Lac levels, but this trend was not statistically significant due to the wide width of the 95% CrI, which included the null value.

With progressing lines of treatment, healthcare consumption showed a trend towards increased non-TKI prescriptions per patient (8 for 2nd line and 9.7 for ≥ 3rd line).

Supporting these qualitative observations, quantitative analysis showed a trend toward decreased BV/TV and increased trabecular thickness, as well as a significant decrease in trabecular number amongst scaffold-treated groups ( Fig. 5 ).

aureus infections showed a trend toward increased treatment success with oxacillin or vancomycin plus rifampicin, although the difference was not statistically significant [ 14 ].

Although not statistically significant, the C allele in the dominant and recessive models also showed a trend toward lower risk of uveitis.

In addition, female sex showed a trend toward a doubled risk of complications but did not reach statistical significance (Figure 3 ). 3.6.

In the case of miR-122-5p, the results showed a trend to be higher in the HCV + group with respect to non-rejectors, but this difference was not statistically significant ( Figure 6C ).

Further, the analysis of patients with low intratumoral expression levels of IL-17A (87 ± 14 months) showed a trend to reduced survival times compared to patients with high intratumoral IL-17A expression (117 ± 11 months) though the difference was not statistically significant (P = 0.211) (Figure 6 B).

The B6 mice in Group 1 had no significant IOP changes between time points, yet showed a trend of slight IOP increase in the older individuals, consistent with normal age-related changes reported in a previous study 22 .