“showed a trend”

The initial stage at initial diagnosis showed a trend toward imbalance, although the difference did not reach statistical significance (P=0.09).

M-D patients showed a trend towards increased metabolism in the parietal cortex and increased severity is correlated with increased FDG uptake.

SuHx-induced KO mice (2.14±0.19 mm) showed a trend towards smaller RV basal compared to WTSuHx (2.57±0.15 mm), but no significant structural changes were observed within the KO groups after PH induction (P=n.s.).

Age and gender do not have a significant effect on disease activity although male gender and older age showed a trend towards higher EDSS score but it was not statistically significant.

Moreover, the associations and exposure–response relationship between TV and lung function parameters before bronchodilation showed a trend similar to that after bronchodilation ( Table S3 and Figure S7 ), and the most pronounced declines were also observed in small-airway flow parameters. 3.3 Mediation Analysis Mediation effects were observed through anxiety and depression scores, accounting for 8.70% (95% CI: 0.02, 17.38) and 9.55% (95% CI: 0.01, 19.09) of the association between temperature variability exposure and COPD, respectively ( Table S6 ).

Although statistical analysis did not reveal a significant association - likely due to the small sample size (N = 5) - patients receiving fluvoxamine showed a trend toward greater clinical improvement ( Figure 5 ).

These results suggested shells assembled normally; however, DLS showed a trend of increasing diameters in the shells with more TPI loading.

Headache-related impact showed a trend toward lower scores in the VSS + MIG group.

Conclusion In this systematic review and meta-analysis of dialysis-dependent CKD, higher n-3 PUFA exposure through supplementation and baseline circulating levels was associated with fewer cardiovascular events and all-cause mortality, respectively, whereas higher dietary intake showed a trend toward decreased mortality that did not reach statistical significance.

The study found that monounsaturated fat intake (MUFA) showed a trend that did not reach statistical significance to decrease breast cancer risk (OR = 0.79; 95% CI: 0.58–1.06).

The results indicated that patients in cluster 2 had a significantly worse prognosis ( Figure 3 E), and cluster 2 showed a trend of poor prognosis in the other nine cohorts ( Figures 3 G–3P; STAR Methods ).

The yellow-blue value (b*) showed a trend of slight initial decline followed by an increase, suggesting that at low addition levels, SSP may have slightly altered the color development characteristics of the PG/SA matrix.

It is noteworthy that although the proportion of resting CD4+ T cells decreased, the proportion of activated CD4+ T cells increased significantly, indicating that CD4+ T cells as a whole showed a trend of transitioning from a resting to an activated state, suggesting that they underwent functional reprogramming in the lymphedema-associated inflammatory microenvironment.

Pathway-level analysis showed a trend toward upregulation of NF-κB/TNF-associated inflammatory genes and STAT1/IFNγ signaling-related genes following EphA3 inhibition (Table S3).

Interim analysis at nine months of the phase 3 trial (APPLAUSE-IgAN) replicated the effect and showed a trend toward improved eGFR preservation.

Serum KL-6 could be a clinically useful biomarker in screening and monitoring CTD-ILD.[ 5 ] Serum levels of CCL-18 and SP-D showed a trend towards negative correlation with FVC, but this was not statistically significant.

However, PD-L1 high expression group (TPS ≥50%) showed a trend toward longer survival (n=4; mPFS =15.93 months, 95% CI: 3.13–NE) compared to PD-L1-negative patients (n=11; mPFS =5.33 months, 95% CI: 4.37–NE), though this difference did not reach statistical significance (P=0.39, Figure 3D ).

However, looking at the changes in EORTC-QLQ-C30 and QLQ-LC13 scores, the addition of chemotherapy showed a trend toward deterioration in fatigue and appetite loss.

The sotorasib-T-DXd combination showed a trend toward greater regressions in tumors with higher HER2 expression post-sotorasib, though these analyses were not powered to detect a difference due to limited sample size ( Figure 2C ).

ARID1A mRNA levels showed a trend for positive correlation with levels of PD-L1 mRNA, but this was not statistically significant ( r = 0.2183, p = 0.2223; Supplementary 1 , Fig. 6B ).

When stratified by UBA1 variant, patients with the p.M41V mutation showed a trend toward higher mean daily GC requirements compared with p.M41L and p.M41T (21.1 ± 7.4 vs. 10.5 ± 3.2 and 13.2 ± 5.6 mg/day), although this difference did not reach statistical significance (p = 0.13, ANOVA; Supplementary Data S3 ).

Strikingly, we found that all members of miR-92 family showed a trend of enrichment in invasive/migrating A549 cells (Fig. 2G ).

In the PFS analysis, patients with a history of liver resection showed a trend toward improved PFS, although this did not reach statistical significance (P<0.10).

Gross excision showed a trend toward improved OS compared with wide excision, but this difference did not reach statistical significance (P=0.08; Figure 5D ).

Although the NAC + DEXA regimen showed a trend toward superiority compared with DEXA or NAC monotherapy, the difference did not reach statistical significance.