Across all cycles, the foot reflexology group showed a trend toward less frequent delayed nausea ( P =.28), a significantly less frequent consumption of antiemetic drugs ( P =.04), and no significant difference for vomiting ( P =.99); there was a trend toward a perception of stronger severity for delayed nausea in the control group ( P =.39).
Cox regression analysis revealed that while PAC with ductal feature was not a significant factor in predicting PSA‐PFS and rPFS, it showed a trend toward improved survival outcomes (PSA‐PFS: HR: 0.63; 95% CI: 0.27−1.46; p = 0.282; rPFS: HR: 0.86; 95% CI: 0.39−1.88; p = 0.698) (Table 2 ). 3.3.
However, the combination group showed a trend toward improved OS (24.8 vs. 16.7 months, P= 0.282), with a significant benefit in BCLC-C patients (17.9 vs. 11.0 months, P= 0.048).
Consistent with prior studies, our data showed a trend toward lower FFR values in the side‐hole group (0.85 [0.75–0.93] vs. 0.90 [0.81–0.92]; p = 0.284).
Using a signature geneset for epithelial-to-mesenchymal transition (EMT), we show that SSc endothelial cells showed a trend toward enrichment in EMT-associated genes ( p = 0.284, Figure 3B ).
Among patients who did not achieve pCR following NCIT, the IT group showed a trend toward improved OS compared with the no-treatment group (HR: 3.08, 95% CI 1.04–9.13, Adjusted P = 0.2856; Fig. 5 b).
cChAT-ir fibers in the pig distal colon showed a trend to have a dose-related decrease in their density induced by loperamide treatment which did not reach significance ( p = 0.286) compared to the control group given vehicle ( Figure 9A ).
Although not reaching a level of statistical significance, the detection sensitivity of the MCA system in CTC enumeration showed a trend toward being greater than that of the CellSearch system (p = 0.2888, Wilcoxon test; Table 3 ).
Silver-coated implants showed a trend toward reduced infection (OR = 0.18, p = 0.29), though not statistically significant.
Although not statistically significant, patients who achieved pCR showed a trend towards longer DFS (P=0.29, Figure 2F ).
Moreover, CS‐exposed WT mice had shorter wire hanging time, which reflects grip strength, compared with the room air‐exposed WT mice, and CS‐exposed Parkin −/− mice showed a trend of further reduction compared with CS‐exposed WT mice ( P = 0.29) ( Figure 5B ).
Considering histopatological features (Table 6 ), no significant difference in cg and microvascular inflammation scores (g, ptc, g + ptc) or C4d positivity was observed between patients with functioning and non-functioning grafts at 24 mo in the PE-IVIG-RTX group, despite the fact that patients with non-functioning grafts showed a trend towards a more pronounced chronicity score at diagnosis (median 0.5 in patients with functioning grafts vs 2 in patients with non-functioning grafts; P = 0.29).
Gene expression of markers for microglia, Ionized calcium-binding adapter molecule 1 ( Iba1) and cluster of differentiation 68 ( Cd68 ), showed a trend of downregulating in SP8-Ap mice compared to SP8-C mice ( Iba1 , p = 0.29, d = 0.22; Cd68 , p = 0.18, d = 0.31).
However, the patients who received DOACs showed a trend toward more major bleeding, with a pooled RR of 1.83 (95% CI: 0.60–5.56; P = 0.29; I2 = 0%; Fig. 6 B) [ 11 , 22 , 24 ].
The effect of PAS on excitability and hemodynamic activity showed a trend of positive correlation with MEP ratios (post-PAS/pre-PAS) linked to HbO and HbR ratios (r = 0.19, p = 0.29; r = 0.18, p = 0.30, respectively).
Severe PD GBA1 variant carriers showed a trend towards younger AAO compared to mild and risk (severe: 58.6 ± 13.1 vs mild: 65.4 ± 17 vs risk: 62.5 ± 9.3 years; p = 0.29) (Table 3 ), with a significant risk to develop early onset PD (OR = 4.02; p = 0.0098).
GAH 0.2–0.4) showed a trend toward better predict of successful ablation sites in the localized reentries, than with macro- and multiple-loop reentries ( p = 0.29) ( Figure 4 B).
Additionally, patients with high-CK showed a trend towards worse PFS versus those with fewer abnormalities (HR, 1.5; 95% CI, 0.7 to 3.4; p = 0.29). he role of CK in venetoclax-based combination was also assessed in treatment-naïve patients following therapy with venetoclax–obinutuzumab (VenG) or cholambucil–obinutuzumab (ClbG) within the CLL14 trial ( 38 ).
Patients with high-GC status showed a trend toward inferior PFS versus those with low-GC status (HR, 1.5; 95% CI, 0.7 to 3.4; P = .29).
Although the normalized rEMG of RF showed a trend toward increasing 10 min after exercise, the change did not reach statistical significance ( p = 0.291 ).
For instance, in the Sirolimus-eluting versus bare nitinol stent for obstructive superficial femoral artery disease (SIROCCO) trial comparing the SMART-sirolimus-eluting stent versus BMS at 6 months, the sirolimus stent group showed a trend toward lower in-stent mean percent diameter stenosis than BMS (22.6% vs 30.9%; P = .294). 82 However, initial enthusiasm was dampened when results at 18 months indicated no significant differences in outcomes. 83 , 84 Similarly, the single-arm STRIDES study evaluating the Dynalink-everolimus-elutin
The study showed a reduction over time in the incidence of common cold ( p value = 0.0032) and showed a trend for a reduction in the incidence of skin conditions ( p value = 0.2950) for the probiotic yoghurt group versus the placebo group.
Renal insufficiency showed a trend toward increased mortality risk (ORa=2.1; 95% CI: 0.5-8.7; p=0.298), as did NYHA functional class IV (ORa=2.8; 95% CI: 0.6-12.4; p=0.184), but neither achieved statistical significance, likely due to the relatively small number of mortality events (n=16) limiting statistical power.
At the same time we also should note that if sampling collection was restricted to the morning, the relationship between fasting LC and BMI just showed a trend ( P = 0.299).
Older age was associated with higher CSF NFL for PWH ( r = 0.303, p = 8.82e-6), and showed a trend for PWoH ( r = 0.164, p = 0.299).