Schizoaffective patients also showed a trend towards a slower psychomotor speed in the TMT-A test when there have been years since having a psychiatric diagnosis ( F = 6.42; df = 1;52; P = 0.01) or the YMRS scores ( F = 4.49; df = 1;49; P = 0.04) were not used as covariates in the analysis (ANCOVA).
In the group that received ES-MSC, the score decreased from 7 days postinfusion compared with the HIE group, which showed a trend of further decrement until 14 days postinfusion ( p < 0.01) ( Figure 1 b).
Indeed, the Tph2 +/– groups showed a trend toward more mounting behaviors than the Tph2 +/+ group ( Figure 2 C, ANOVA: F 2,23 = 7.21, p < 0.01, permutation test: g Tph2+/+<Tph2+/– = 0.64 [−0.42; 1.36], p = 0.16).
However, at 1 month post-injury, a shift occurred where individuals with TBI significantly favored VIS+ and showed a trend of favoring VIS- (t = −2.65, uncorrected p = 0.01, corrected p = 0.03 and t = −2.02, uncorrected p = 0.05, corrected p = 0.07) while disfavoring DMN+ and showing a trend of disfavoring DMN- (t = 2.60, uncorrected p = 0.01, corrected p = 0.03 and t = 2.04, uncorrected p = 0.04, corrected p = 0.07) compared to controls ( Fig. 2 A).
Knees with normal SMI were prone to be designated as K/L grade 0 or 1; however, subjects with sarcopenia showed a trend toward the higher K/L grade, classified as knee radiological osteoarthritis (ROA) ( p < 0.01).
Although current symptoms were generally not significantly associated with sibship size, the exception was current flexural dermatitis which showed a trend ( P < 0.01) to be more common in larger families.
Notably, plasma IL-6 and monocyte IL-6 levels were non-correlated at baseline (rho = −0.09, p = 0.74), but the stress-induced change in plasma and monocyte IL-6 concentrations showed a trend to correlation (rho = −0.64, p = 0.01).
When the data were averaged across animals on days 7–9 post-exposure, those exposed at 110 showed a trend suggestive of startle enhancements at high startle stimulus levels (≥105 dB SPL) (F 3,72 = 6.21, P = 0.01), but the enhancement was significant only at a startle stimulus level of 110 dB SPL (T 9 = 1.83, P = 0.05) ( Fig. 4B ).
This group showed a trend for wild-type BRAF and MACROD2 deletions (Fisher's exact test, P =0.01 and 0.02, respectively) and was associated with a specific DNA methylation pattern, namely cluster_4 ( P =0.0057, Chi-square test) ( Supplementary Fig. 10 ).
We also found that Ara-C-treated rmTBI mice showed a trend toward rescue of enhanced Prox-1+/BrdU+ cell numbers seen in the vehicle rmTBI DG (Fig. 2 C, F–I) (F (3,24) = 4.35; p = 0.01).
The LPS+5 μg/ml TRP group showed a trend of reduced inhibition of cell viability compared to the LPS group (P < 0.01).
This is in line with a preliminary report of 11 DBN patients which showed a trend (uncorrected data p<0.01) for vermal atrophy (lobules V,VI) [ 42 ].
Western blot analysis—In neonatal, ENDO showed a trend of expression, characterized by a significant increase from the inner to outer part of the meniscus (Fig. 3 , P < 0.01), while young and adult animals revealed no quantitative differences among the different meniscal areas (Fig. 3 , P > 0.05); furthermore, pooling the three zones, the young meniscus revealed a significantly higher expression of ENDO in comparison with neonatal and adult ones ( P < 0.01).
The simple effects of the CMJ showed a trend that PAPE peaked at T4 ( p < 0.01) and almost subsided at T12 ( p > 0.05) in ML and P conditions.
Similar to the mtDNA, the CpG sites in 45S rRNA showed a trend for differences in the mean MF between plus- and minus-strands in five individuals ( Supplementary Figure 5B , Mann Whitney U-test p < 0.0101, difference in mean MF <0.014).
Coch +/– mice showed a trend toward lower DPOAE threshold shifts than wild-type mice, which reached significance at 11.33 kHZ (mean difference = 13.28 dB SPL, P = 0.0103) and 45.25 kHz (mean difference = 13.04 dB SPL, P = 0.0121).
Consistent with the results from the blood-based biomarkers, patients with increasing LV exhibited lower GM volume both at baseline (mean GMF: 0.43 ± 0.04 vs 0.44 ± 0.03; p = 0.0209), which showed a trend after FDR correction ( q = 0.0627), and at follow-up (mean GMF: 0.42 ± 0.04 vs 0.44 ± 0.03; p = 0.0109), which remained significant after correction ( q = 0.0490; Table 2 ).
While Q2 and Q3 showed a trend toward lower mortality risk compared to Q1, only Q3 reached statistical significance in Model 3 (HR = 0.737, 95% CI: 0.583–0.931, p = 0.011), suggesting a dose–response relationship primarily driven by higher adherence to MDS.
Younger participants showed a trend-level preference for pictures in the ‘Space’ ( F (1,183) = 6.7, p = 0.011) category. ‘Liking’ ratings for ‘HAI’ and ‘HTD’ categories A repeated measures ANCOVA yielded a significant main effect of category ( F (1,183) = 7.4, p = 0.007) and interactions between category and age ( F (1,183) = 12.5, p = 0.001), category and diagnosis ( F (1,183) = 15.2, p < 0.001), and category and gender ( F (1,183) = 19.4, p < 0.001; Figs 2B , 3B and 4B ).
However, the overweight/obesity group showed a trend toward longer OS, particularly in patients receiving IO–IO regimens (P = 0.011).
Within the L-TLE group, only the hippocampus showed a trend toward lower volume in the ipsilateral vs. contralateral side (p = 0.011).
Although the data showed a trend toward amplitude differences between groups on multiple peaks, the PASC and controls groups differed only on wave I amplitude in the grand mean ( p = .011) and using the fast click rate ( p = .006) with controls having larger amplitudes (Supplementary Table 1).
Results We did not observe obvious correlation between patients’ disease features and STAT3 polymorphisms, but patients with homozygous genotypes at rs2293162 showed a trend of higher CR rate than those with the heterozygous genotype, especially in non-GCB subgroup ( p = 0.011).
Within the white matter, the Light Cyan module (12c) showed a trend towards differential expression across the four clinical groups (p = .011; Figure 4 , Panel B).
1·79 to 4·96; P < 0·001) and preoperative anaemia showed a trend (OR 1·91, 1·16 to 3·16; P = 0·011).