showed a trendP <0.01
Over four weeks, immediate and double-injection groups considerably showed a trend of increase in BMS scores that become significantly different compared to the control (vehicle treatment) group ( P <0.01).
Over four weeks, immediate and double-injection groups considerably showed a trend of increase in BMS scores that become significantly different compared to the control (vehicle treatment) group ( P <0.01).
Generally, the quantified proteins showed a trend to be up-regulated in CB4856 and in the RILs relative to N2 ( P ≤ 0.01; Fig 3A ), and about a quarter of the protein abundance changes were both statistically significant ( P ≤ 0.05) and above the fold change cut-off of 1.3 (~ 0.38 on log 2 scale; Fig 3A and S6 Fig ).
Adults over 75 years showed lower perceived stress (b = −7.13 p = 0.05, [95% CI −14.29 to −0.03]), females showed more stress than males (b = 3.17, p < 0.000 [95% CI 2.19 to 4.16]), as did some college/no degree (b = 3.25, p < 0.05, [95% CI 0.02 to 6.48]) and four-year degree holders (b = 3.28, p < 0.05, [95% CI 0.18 to 6.38]); doctoral degree holders showed a trend for more stress (b = 2.74, p < 0.01, [95% CI −0.44 to 5.92]) as did students (b = 1.82, p < 0.01, [95% CI −0.15 to 3.79]).
The LPS+5 μg/ml TRP group showed a trend of reduced inhibition of cell viability compared to the LPS group (P < 0.01).
The results from 15 Dobermann Pinscher female dogs showed a trend of increase of the coat C from mating to 60 days post-partum, with significant changes between mating and parturition-60 days post-partum ( p < 0.01) and between the 30-day pregnancy diagnosis (PD) and 30–60 days post-partum ( p < 0.05).
Schizoaffective patients also showed a trend towards a slower psychomotor speed in the TMT-A test when there have been years since having a psychiatric diagnosis ( F = 6.42; df = 1;52; P = 0.01) or the YMRS scores ( F = 4.49; df = 1;49; P = 0.04) were not used as covariates in the analysis (ANCOVA).
This group showed a trend for wild-type BRAF and MACROD2 deletions (Fisher's exact test, P =0.01 and 0.02, respectively) and was associated with a specific DNA methylation pattern, namely cluster_4 ( P =0.0057, Chi-square test) ( Supplementary Fig. 10 ).
The mean FSAT-KBD score showed a trend similar to that of the Harris score and improved from 27.69 ± 2.91 at baseline to its peak of 36.81 ± 3.44 ( p < 0.01 vs. baseline) at 2 years after the surgery.
When the data were averaged across animals on days 7–9 post-exposure, those exposed at 110 showed a trend suggestive of startle enhancements at high startle stimulus levels (≥105 dB SPL) (F 3,72 = 6.21, P = 0.01), but the enhancement was significant only at a startle stimulus level of 110 dB SPL (T 9 = 1.83, P = 0.05) ( Fig. 4B ).
Pseudotumor cerebri patients showed a trend of lowered CSF protein concentrations ( p = 0.01).
In addition, the ROC curve analysis of WA% to distinguish severe from non-severe asthma patients showed a trend to a lower AUC using an optimal cutoff of WA% of 73% (AUC = 0.74; 95% CI: 0.54–0.88) ( p = 0.01, Supplementary Fig.
Within the breathing control subgroup, gastroesophageal reflux disease questionnaire (GERDQ) scores showed a trend favoring the abdominal breathing regimen (SMD = −0.74; 95% CI: −2.06 to 0.57), though this did not reach statistical significance, and heterogeneity remained high ( I 2 = 85.9%, p < 0.01).
The excessive release of IL-22 in lung tissue may stimulate the expression of RegIIIγ in intestinal tissue via the circulation Compared with the normal group, the expression of IFN-γ in the lungs and intestines of the RSV-infected group showed a trend of first increasing and then decreasing, reaching a maximum value one the third day after infection, with a significant difference ( P < 0.01, Fig. 4A ).
The simple effects of the CMJ showed a trend that PAPE peaked at T4 ( p < 0.01) and almost subsided at T12 ( p > 0.05) in ML and P conditions.
Similarly, 10 studies showed a trend toward lower CK-MB levels compared with controls (n = 10; SMD = −4.35; 95% CI: −5.59 to −3.11; heterogeneity: I 2 = 57%; P = 0.01; Figure 4C ).
Although nine CpG sites showed a trend in association with clinical stage (p<0.01) ( Table 3 ), the data analysis did not reveal significant difference among the three stages (all CpG sites with FDR >0.05).
Surprisingly, a gene encoding for another myosin heavy chain component, MYH7 , showed a trend towards AL (log2 FC = 0.921, q = 0.076), a difference boosted by qPCR (log2 FC = 1.025, p < 0.01).
When pooled across studies, TMB-high compared with TMB-low showed a trend toward improved PFS (pooled HR 0.47, 95% CI 0.33–0.7, p < 0.01).
SNPs that showed a trend for association (7 SNPs with p ≤ 0.01) with either maximum BMI in adulthood or maximum BMI z score in childhood, or were predicted to be damaging using the Ingenuity Variant Analysis (rs11872992) were further genotyped in all remaining subjects ( n = 3,852, mixed-heritage American Indians, Supplementary Table 1).
Linc-ROR also showed a trend of increasing expression in patients with more advanced clinical phases of ovarian cancer ( P <0.01), while patients with lymph node metastases had higher linc-ROR expression than those without ( P <0.01).
As the main results of this study, pancreatic cancer cases showed a trend for a higher median of 8-OHdG as well as a significant trend when the level of 8-OHdG was categorized in Quartile scale [1.50 (1.09, 2.06) (P=0.01)].
However, exposure to ASU for 72 h showed a trend toward an increase ( P < 0.01) in positive dose response ( Fig. 4 ).
A χ 2 test revealed no statistically significant differences in the RBS-R individual item endorsements between UIC and UF samples; however, the item 14 “skin picking” showed a trend for a higher endorsement in the UF sample than in the UIC sample ( χ 2 = 6.68, df = 1, p = 0.010).
As shown in Figure 3 D, 3 weeks post‐lesion, unilateral lesioned rats injected with 6‐OHDA showed a trend of increased contralateral rotation after apomorphine administration compared with the vehicle group ( P < 0.01), but there was no significant difference between the 6‐OHDA group and the 6‐OHDA plus ECH group ( P > 0.05).
Notably, plasma IL-6 and monocyte IL-6 levels were non-correlated at baseline (rho = −0.09, p = 0.74), but the stress-induced change in plasma and monocyte IL-6 concentrations showed a trend to correlation (rho = −0.64, p = 0.01).