The pooled data reached borderline significance in support for overall survival advantage in favour of SRT with an HR of 0.90 [95% CI, 0.81 to 1.00; P = 0.05] (three trials, 2574 patients; Fig. 2B ).
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No clearly significant difference was observed between the sexes either, though p-value reached borderline significance (z test z = 1.93, p = 0.05): age-standardized incidence was 1.86/100,000 (95% CI 1.65–2.07) for men and 2.16/100,000 (95% CI 1.94–2.39) for women, so confidence intervals were largely overlapping.
Total revision surgery(ies) costs were greater in patients with prepectoral implants than those with subpectoral implants, though this difference reached borderline significance ($3154 versus $1636 respectively, p=0.05 ).
The end of treatment differences in the average vitreous chamber depths between the control and treated animals reached borderline significance for the 18:82 monkeys (9.55 ± 0.25 mm, P = 0.05), but not for the 25:75 subject group (9.74 ± 0.28 mm, P = 0.52).
Patients were diagnosed with HNC at a mean of 12.6 years after their diagnosis of RA in the nbDMARD group compared to 12.3 years in the TNFi group; this difference reached borderline significance (p = 0.05).
[ 16 ] were excluded because control group genotypes reached borderline significance for HWE (p = 0.05), and the results of Sale et al.
approached significancep = 0.07
While not significant in crude analyses (HR = 0.86, 95% CI: 0.68–1.07, p = 0.17), the association approached significance in Model 1 (HR = 0.78, 95% CI: 0.60–1.02, p = 0.07) and reached borderline significance in the fully adjusted model (HR = 0.76, 95% CI: 0.58–1.00, p = 0.05).
In contrast, no statistically significant differences in mean OHL scores were observed according or household income (p=0.63), while the difference by sex reached borderline significance ( p =0.05).
However, symptom–arrhythmia correlation was not significant in the symptomatic group ( P = .266) but reached borderline significance in the screening group ( P = .050).
Although this difference reached borderline significance in the univariate analysis ( p = 0.05), its relevance to the overall toxicological profile was robustly substantiated by subsequent multivariate analyses (see Section 2.5 ), where it was identified as a key driver of the toxicity model.
Nevertheless, two genes related to the phagocytosis signature, clec4n and clec4e were found upregulated in N1 (adjusted p-value < 0.01), whilst hif1α , involved in NET release [ 34 ], reached borderline significance (p-value < 0.05, adjusted p value = 0.11) in N2 ( Fig 6D ).
In a multivariate Cox proportional-hazards regression analysis, high fascin expression only reached borderline significance as an independent predictor of poor survival, with a hazard ratio of 0.663 (95% confidence interval: 0.44−1; P = .05) ( Supplementary Table 1 ).
The association of titin Abs with the haplotype DRB1*07‐DQB1*02 reached borderline significance ( P = 0.0504).
Males reached borderline significance, with the TC genotype being more highly represented in the CD subtype ( p = 0.051), despite reaching overall model significance ( p = 0.007).
Addition of biomarkers resulted in significantly improved discriminatory ability ( C -index 0.83, Δ C 0.032; 95% CI 0.015–0.049; P < 0.001) and the addition of the PRS reached borderline significance ( C -index 0.82, Δ C 0.020; 95% CI 0.000–0.040; P = 0.051).
borderline significancep=.051
Breastfeeding for more than 1 month approached borderline significance (OR=2.06, p=.051) in predicting AD and air filter use reached borderline significance in predicting protection from AD (OR=0.43, p=.053).
Independent-samples t tests showed that the baseball players were superior to the nonathletes in all four aspects of ocular-tracking performance, as indicated by 8 out of 12 oculometric measures: shorter latency ( t (84) = 2.84, p = 0.0056, Cohen's d = 0.61), larger open-loop acceleration that reached borderline significance ( t ( 84 ) = 1.98, p = 0.051, Cohen's d = 0.43), larger steady-state gain ( t (84) = 4.12, p < 0.001, Cohen's d = 0.89), smaller catch-up saccade amplitude ( t (84) = 2.98, p = 0.0038, Cohen's d = 0.64) and dispersion ( t (84) = 2.78, p = 0.0068, Cohen's d = 0.60), smaller direction noise ( t (84) = 3.48, p < 0.001, Cohen's d = 0.75) and vertical-horizontal asymmetry ( t (84) = 2.49, p = 0.015, Cohen's d = 0.54), and larger speed responsiveness ( t (84) = 2.50, p = 0.014, Cohen's d = 0.54).
PSMA + CTCs ( Figure 2B ) also associated with a reduced OS ( p = 0.0059) while AR-V7 + CTCs ( Figure 2D ) reached borderline significance ( p = 0.051).
Genes upregulated with both S6K1 and S6K2 knock-down included the mTORC1 factor Raptor, (which also reached borderline significance for double knock-down, p = 0.051) ( Table 5 ) , as well as the adhesion molecules CDH1, TLN1 (talin1) and CADM4 and the cell cycle associated genes RAD51C and TOP2B.
The mean infarct volume at 48 hours (Table 4 ; Figure 2 B) did not significantly differ in RIC+ mice compared with RIC− mice in the unadjusted analysis (27.8 versus 32.5 mm3; mean difference, −4.7 [95% CI, −10.2 to 0.9]; P =0.097), but this difference reached borderline significance in the sex-stratified analysis ( P =0.051).
Moreover, for novel words, although both groups showed increases between the two delays, this effect reached borderline significance for the SLI group ( F (1, 20) = 4.314, p = .051, η p 2 = .177) but not for the TD group ( F (1, 20) = 1.591, p = .222, η p 2 = .074).
The difference in OR estimates between class S allele carriers and non-carriers reached borderline significance ( p = 0.051) at an level arsenic exposure exceeding 750 μg/L in the LMN cohort.
Although fasting triglycerides were low in each gender, this reached borderline significance ( P = .052) in men alone (by one-sixth).
Across practice sub‐domains, differences were modest and directionally consistent (R1 ≥ 4o > V3); the Diagnostics sub‐domain reached borderline significance driven by V3’s lower scores (F(2,12) = 3.82, p = 0.052; Tukey R1 vs.
It is also important that the path from Maternal Grandmother to Thrifty Phenotype reached borderline significance (β = -0.19, p = 0.052).