“reached borderline significance”

However, the observed associations reached borderline significance only, after correcting for multiple testing.

In their study, Ki-67 immunostaining was a significant prognostic factor in univariate analysis, whereas S- phase only reached borderline significance.

CDC was independently predicted by child age at follow-up, and for CBSI, age reached borderline significance as a predictor.

Improvement in the instructional support scale also reached borderline significance.

For all 3 tested diseases, the effects only reached borderline significance in some sensitivity analyses when restricting the study population (see S2 Text ).

Since the prognostic role of AR in GC and the potential mechanisms are insufficient, even though the association of AR with PFS only reached borderline significance in the present study, we performed in vitro experiment, and revealed that downregulation of AR suppressed the migratory and invasive ability of GC cells, possibly via inhibition of EMT associated molecules including α-SMA, β-catenin, snail, and slug.

Finally, we tested whether age at diagnosis affected the slope of decline of C-peptide by adding an interaction term (model 4), and this effect reached borderline significance, indicating that older children had a less steep decline in C-peptide over time.

47 , 53 – 56 Moreover, the effects’ size for improvement in ABC hyperactivity subscale was small and only reached borderline significance (Hedges’ g =−0.348, 95% CI =−0.716 to 0.021).

( 46 ) and the Digit Symbol Coding Test only reached borderline significance when work history was entered into the model ( 50 ).

In the luteal phase the levels reached borderline significance with a p-value of 0.07 but no changes were seen after tamoxifen therapy, Figure 2 . miRNA-193b, -203, -451, and -452 were unaltered in breast cancers but in normal breast tissue miRNA-193b and miRNA-203 exhibited significantly decreased levels in postmenopausal breast tissue and increased levels in the luteal phase of the menstrual cycle suggesting that hormone exposure may affect their levels, Figure 3 .

However, the association between elevated MR‐proADM and short‐term mortality only reached borderline significance after multivariable adjustment, and MR‐proADM did not add clinical relevant prognostic information to multivariable receiver operating characteristics analysis on either short‐ or long‐term all‐cause mortality.

Operative duration using the robotic platform was significantly longer versus laparoscopy, which is consistent with existing published studies although this only reached borderline significance within the colorectal cancer subgroup [ 28 , 54 ].

The natural history study by the COG evaluated multiple clinical risk factors and only time to TAM resolution reached borderline significance with leukemia-free survival ( Gamis et al. 2011 ).

In the entire cohort, age (HR = 1.031, 95% CI 1.013–1.049, p = 0.001), ECOG (HR = 2.176, 95% CI 1.644–2.880, p < 0.001), T stage (HR = 1.315, 95% CI 1.872–1.613, p = 0.009) and concomitant systemic treatment (HR = 0.511, 95% CI 0.333–0.783, p = 0.002) were prognosticators for OS, while the prognostic value of peritherapeutic antibiotic administration (HR = 1.407, 95% CI 0.995–1.990, p = 0.053) reached borderline significance (Table 3 ).

IL-1 was positively associated with PFOA ( p = 0.088), while IL-6 was positively associated with PFOS ( p = 0.068), although these values only reached borderline significance. 4.

Mean intake of protein from dairy products was also higher among LCT heterozygotes and TT homozygotes, respectively, although this association only reached borderline significance.

SBP reduction in the garlic-4 group reached borderline significance at 8 weeks compared with placebo.

Importantly, the primary endpoint reached borderline significance, while the study was powered for a 10-year follow-up [ 28 ].

After adjustments for covariates, the trend of the association remained the same for the intake of vegetables ≥2 servings a day and reached borderline significance for an intake of red meat less than once a day in the fully adjusted model. 4 Discussion The present study aimed to determine the relationship between AMD and depressive symptoms as well as to identify specific food components of the MD and social factors that could serve as preventive and modifiable factors against depression in Lebanese adults.

The difference in Muc1 expression only reached borderline significance.

This analysis of a patient collective, having undergone resection of brain metastases, did not confirm the relevance of hemodynamic parameters, as the mean intraoperative diastolic blood pressure only reached borderline significance.

Self-reported very good and good mental health status reached borderline significance with lower frequency in AF individuals with heart failure (64.9% versus 80.5% in individuals without heart failure; ).

For the first time, we found a possible association of FCN1 polymorphism with multiple myeloma: the genotype G/A-C/C-G/G (at positions −542, −144, and +6658, respectively) was more common among patients than among controls, although the difference only reached borderline significance.

Although the UTI difference reached borderline significance, the absolute difference of 1.4% is probably clinically meaningful, possibly reflecting the large sample size.

In the univariate analysis, Mayo risk score (p = 0.02) and biliary candidiasis (p = 0.006) were associated with reduced survival, whereas presence of dominant stenosis and IBD reached borderline significance.