Although this association only reached borderline significance, we suspect that it might be of importance given the relatively large effect size.
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26 ± 5.0 days, P = 0.079), a difference that reached borderline significance.
In multivariate Cox analysis, the nodal status was verified as the single highly significant predictor of mortality, whereas alcohol consumption only reached borderline significance.
Incidence of implantable cardioverter-defibrillator (ICD) was significantly elevated in the HF group and reached borderline significance as far as frequency of dual chamber permanent pacemaker (DDDR) was concerned.
The IIEF-5 score was highest in the PVS group at all time points after surgery with a median score of 18 vs 7.5 in the control group at 12 months ( P = 0.09), but the difference only reached borderline significance.
Furthermore, although p values reached borderline significance, these cells might be associated with worse outcome which finally has to be proven in a bigger patient cohort.
Larger studies are needed to confirm the significance of other factors such as educational status, parity and the number of lifetime partners that reached borderline significance in relation to CIN 2 or 3 in our study.
When analysis was performed on both shaved and unshaved mice ( n = 10) with the fur effect blocked, only two genes (Cd276 and Daglb) reached borderline significance at FDR = 0.049.
Although LD score regression analysis showed no statistically significant association between adiponectin and RA, it suggested a potential association as the p -value reached borderline significance.
Similarly, nerve conduction studies showed more severe axonal damage in ALS patients with rare DHTKD1 variants compared to non-variant carriers, although these results only reached borderline significance.
Race reached borderline significance, while older age and public insurance trended toward significance, hinting at structural barriers that require confirmation in larger cohorts.
Even if the difference reached borderline significance only, application of a quantification tool might facilitate objective differentiation.
EVT + 0.0625 mg/kg TNK reached borderline significance, likely reflecting increased statistical power from pooling three underpowered direct-comparison studies ( Huang et al., 2025 ; Hu et al., 2025 ; Hou et al., 2025 ).
Two SNPs reached borderline significance (rs10832417-T, β = 0.547, FDR < 0.1; rs7103496, β = 0.676, FDR < 0.1).
Among the IBD patients included in our study, the UC patients had a higher age (on average almost 10 years older), compared to the control group and CD patients, although the statistical significance of this difference reached borderline significance.
The p ‐value for a treatment‐by‐sex interaction reached borderline significance for two of the three primary endpoints ( p for interaction 0.13, 0.30, and 0.104, respectively).
The interaction term between serum alpha-Klotho and TyG index reached borderline significance, supporting a postulate of potential synergistic effect of serum alpha-Klotho and TyG index on the risk of CVD. 3.4.
Our analysis indicated a trend toward more asymmetric divisions in irradiated organoids, which reached borderline significance for those irradiated with 0.5 Gy ( Figures 4 H and 4I).
Risk Stratification for Twelve-Month Survival Both models reached borderline significance in differentiating a low-risk cohort from a high-risk cohort for twelve-month survival, with the extended model performing with slight superiority over the baseline model ( p = 0.06 vs. p = 0.08).
Flow cytometric analysis of TMRE fluorescence revealed a marginal increase in oxLDL trained macrophages treated with SRT1720, which reached borderline significance ( Figure 4D ; right panel).
Another important aspect to consider is the higher prevalence of prediabetes in the empagliflozin arm at baseline (randomization visit) (Table 1 ), which could represent a conservative bias that could have obscured a positive result, since the worsening of glucose tolerance status reached borderline significance in favour of empagliflozin.
The results on COVID-19 related hospitalization and mortality upon hospitalization for COVID-19 infection also reached borderline significance.
The correlation between VA estimates of EGFL7 and miRNA-126 in the lymph node metastases only reached borderline significance, tentatively supporting a positive correlation between the estimates.
Because our study population was a heterogeneous mixture of asymptomatic moderate to severe AS patients, it is possible that some parameters that reached borderline significance would predict outcome in a subgroup analysis.
The SNP rs757210 was found to be associated with promoter methylation in high-grade serous carcinoma (HGSC), and its involvement also reached borderline significance in ovarian clear cell carcinoma (OCCC) ( 5 ).