“nominally significant”

While the test of homogeneity was only nominally significant ( p = 0.046), six of the seven ORs were greater than one.

Influences of SLC1A1 SNPs on IRI In single SNP analyses, nominally significant associations were observed between rs301443 and PT ( p = 0.046), rs3780412 and FS ( p = 0.044), rs2228622 and PD ( p = 0.034), and rs3780412 and PD ( p = 0.016) ( S6 – S9 Tables).

3.5 Sleep disturbance score and rate of brain Aβ accumulation After Bonferroni correction for multiple comparisons, a nominally significant three‐way interaction was observed among moderate/severe sleep disturbance, APOE ε4 carriage, and time (β = 2.35 ± 1.17, P = 0.046), with respect to rate of brain Aβ accumulation.

For the APD traits, only the DRD2 TaqID SNP showed a nominally significant association (p = 0.046) which did not remain significant after correcting for multiple comparisons.

In addition, a positive correlation between symptom severity and physical activity levels was nominally significant (ρ = 0.32, p = 0.046, q = 0.514) ( Figure 2 A, Supplemental Table S3 ).

For the overall participants, the plasma concentrations of Aβ42 were nominally significant for subjects carrying the rs1784933 G allele having a lower level than those without the G allele ( p = 0.046).

The GGN microsatellite in exon 1 of the AR gene showed modest nominally significant associations between a dichotomous (homozygous major allele GGN 23 carried by 70% of individuals vs rest) measure and two outcomes: child IQ (r = −0.104, p = 0.046) and anxiety symptoms (r = 0.096, p = 0.040).

The only nominally significant interaction was with active smoking (HP×active smoking OR 0.65, p=0.046; table 3 ).

In the fully adjusted model including Total WMH and CMC, standardized β coefficients were −0.005 (95% CI, −0.064 to 0.054; p = 0.87) for reaction time, −0.007 (95% CI, −0.065 to 0.052; p = 0.82) for Trail Making Test–B, −0.058 (95% CI, −0.116 to −0.001; p = 0.046, nominally significant) for fluid intelligence, and −0.019 (95% CI, −0.110 to 0.072; p = 0.68) for digit span.

Mendelian randomization osteoarthritis dehydroepiandrosterone sulfate estradiol testosterone dihydrotestosterone Causal Association Between Sex Steroid Levels and OA by Sex The nominally significant results of IVW analyses showed that serum DHT level tended to have a causal effect on the risk of OA in women (OR=1.012, 95% CI: 1.000–1.025; P=0.046), while no relationship was observed between sex steroid levels and OA risk in men ( Figure 3 ).

The P ‐value for the interaction of prior HF was nominally significant ( P = 0.046); however, this was not controlled for multiple comparisons. 3.4 Time to first occurrence of MACE in the phase 3a glycaemic efficacy trials In the combined SUSTAIN and PIONEER glycaemic efficacy trials, the incidence rates for MACE were 0.7 and 0.9 events per 100 subject‐years with semaglutide and comparator, respectively (HR 0.85 [95% CI 0.55, 1.33]; Figure 4 ).

However, the lower dose of tiotropium 2.5 μ g did show nominally significant improvement in peak FEV 1(0–3h) response versus placebo add-on at Week 12 (111 mL, 95% CI 2–220, P=0.046).

The interaction between ancestry and WHR for HbA1c was nominally significant for EA ( β = 6.42 ± 3.22, p = 0.046) and SA ( β = 3.05 ± 1.33, p = 0.02) (Table S10 ).

Similar effects were observed without the HbA1c adjustment, as well as a nominally significant reduction by 4.8% in the intensive group ( P =0.046).

For ΔDSL, the interaction term was nominally significant (β = −0.605, 95% CI −1.198 to −0.012; p = 0.046); because this analysis was exploratory and the study was not powered for interaction testing, this finding was interpreted cautiously and not taken as evidence of a confirmed modifying effect.

According to the Chao index of alpha diversity analysis, HFpEF patients showed a nominally significant lower species richness when compared with controls ( P = 0.046).

Using human genetic data from the 1000 Genomes Project, we calculated the DH value for the NOVA1 locus, which was nominally significant at p = 0.046.

Subsequently, we used a t ‐test to compare the ME between AD+P and AD−P samples, identifying six nominally significant modules (darkgreen: N = 1023 probes, p = 0.046; firebrick4: N = 122 probes, p = 0.025; darkseagreen3: N = 105 probes, p = .012; magenta: N = 6368 probes, p = 0.030; grey60: N = 1830, p = 0.018; greenyellow: N = 5512 probes, p = 0.045).

SNP rs2241164 was also nominally significant in the independent replication sample ( P = 0.0462, OR = 1.110), and the significance became stronger in a subsequent meta-analysis combining both discovery and replication samples ( P = 0.00398, OR = 1.138).

Overall, a total of thirty-one SNPs were nominally significant (2.34 × 10 −4 < p < 4.66 × 10 −2 ) in this single SNP analysis.

Although a nominally significant difference was found between Grade II and Grade IV ( p = 0.0466), this did not remain significant after Bonferroni correction.

No PMO were significant predictors of pre-weaning mortality rate, although 2′FL concentration was nominally significant prior to FDR correction ( P = 0.0466), with an increase in 2′FL concentration associated with a decrease in pre-weaning mortality rate ( R 2 = 0.332; β = −0.510).

Changes in airway volume were generally consistent across lobes for both treatments; however, the untransformed analysis of untrimmed iVaw by airway generation showed a nominally significant interaction between treatment and generation ( p = 0.0469), indicating potential differences in the effects of GP MDI and FF MDI by generation ( Figure 3(a) ).

Notably, several KEGG “disease” or host-associated annotation categories (e.g., toxoplasmosis, small cell lung cancer, p53 signaling, influenza A, viral myocarditis, colorectal cancer) appeared among nominally significant features (all P ≈ 0.047) but displayed effect sizes close to zero.

Repeated-measures ANOVA showed a nominally significant effect of time (F(3, 213) = 2.699, p = 0.047, η p 2 = 0.037), although the Greenhouse–Geisser-corrected result was no longer statistically significant ( p = 0.052).